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The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern

Nature communications, 2022-02, Vol.13 (1), p.719-719, Article 719

2022

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Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening

Nature communications, 2021-12, Vol.12 (1), p.7127-10, Article 7127

2021

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Synthesis of a Nucleobase-Modified ProTide Library

Organic letters, 2016-11, Vol.18 (22), p.5816-5819

2016

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Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model

The Journal of infectious diseases, 2021-09, Vol.224 (5), p.749-753

2021

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Overview of Biologically Active Nucleoside Phosphonates

Frontiers in chemistry, 2021-01, Vol.8, p.616863-616863

2021

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Synthesis of benzo[d]isothiazoles: an update

ARKIVOC free online journal of organic chemistry, 2024-01, Vol.2024 (5)

2024

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Synthesis and Structure–Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3‑b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity

Journal of medicinal chemistry, 2019-06, Vol.62 (12), p.5810-5831

2019

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Synthesis of a 3,7-Disubstituted Isothiazolo[4,3- b ]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase

Molecules (Basel, Switzerland), 2024-02, Vol.29 (5), p.954

2024

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Combination of the parent analogue of remdesivir (GS-441524) and molnupiravir results in a markedly potent antiviral effect in SARS-CoV-2 infected Syrian hamsters

Frontiers in pharmacology, 2022-12, Vol.13, p.1072202

2022

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The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

EBioMedicine, 2021-10, Vol.72, p.103595-103595, Article 103595

2021

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Exploration of Pyrido[3,4- d ]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2

Molecules (Basel, Switzerland), 2023-02, Vol.28 (5), p.2099

2023

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Synthesis and Biological Evaluation of Pyrrolo[2,1‐f][1,2,4]triazine C‐Nucleosides with a Ribose, 2′‐Deoxyribose, and 2′,3′‐Dideoxyribose Sugar Moiety

ChemMedChem, 2018-01, Vol.13 (1), p.97-104

2018

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Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis

Molecules (Basel, Switzerland), 2023-04, Vol.28 (7), p.3222

2023

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Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3 H )-Ones with Antiproliferative Activities

Molecules (Basel, Switzerland), 2023-12, Vol.28 (23), p.7912

2023

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Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists

Molecules (Basel, Switzerland), 2021-10, Vol.26 (20), p.6297

2021

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A Scaffold‐Hopping Strategy toward the Identification of Inhibitors of Cyclin G Associated Kinase

ChemMedChem, 2019-01, Vol.14 (2), p.237-254

2019

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Synthesis and Anti‐HIV Activity of Guanine Modified Fluorinated Acyclic Nucleoside Phosphonate Derivatives

Chemistry & biodiversity, 2019-02, Vol.16 (2), p.e1800532-n/a

2019

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Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors

Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.160

2022

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Selective Inhibitors of Cyclin G Associated Kinase (GAK) as Anti-Hepatitis C Agents

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3393-3410

2015

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Amidate Prodrugs of Deoxythreosyl Nucleoside Phosphonates as Dual Inhibitors of HIV and HBV Replication

Journal of medicinal chemistry, 2016-10, Vol.59 (20), p.9513-9531

2016

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Synthesis of novel 5-amino-thiazolo[4,5-d]pyrimidines as E. coli and S. aureus SecA inhibitors

Bioorganic & medicinal chemistry, 2011-01, Vol.19 (1), p.702-714

2011

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Biopharmaceutical profiling of a pyrido[4,3-d] pyrimidine compound library

International journal of pharmaceutics, 2013-10, Vol.455 (1-2), p.19-30

2013

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The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern

Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening

Synthesis of a Nucleobase-Modified ProTide Library

Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication

Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model

Overview of Biologically Active Nucleoside Phosphonates

Synthesis of benzo[d]isothiazoles: an update

Synthesis and Structure–Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3‑b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity

Synthesis of a 3,7-Disubstituted Isothiazolo[4,3- b ]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase

Combination of the parent analogue of remdesivir (GS-441524) and molnupiravir results in a markedly potent antiviral effect in SARS-CoV-2 infected Syrian hamsters

The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir

The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

Exploration of Pyrido[3,4- d ]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2

Synthesis and Biological Evaluation of Pyrrolo[2,1‐f][1,2,4]triazine C‐Nucleosides with a Ribose, 2′‐Deoxyribose, and 2′,3′‐Dideoxyribose Sugar Moiety

Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis

Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3 H )-Ones with Antiproliferative Activities

Identification of Inhibitors of SARS-CoV‑2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen

Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists

A Scaffold‐Hopping Strategy toward the Identification of Inhibitors of Cyclin G Associated Kinase

Synthesis and Anti‐HIV Activity of Guanine Modified Fluorinated Acyclic Nucleoside Phosphonate Derivatives

Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors

Selective Inhibitors of Cyclin G Associated Kinase (GAK) as Anti-Hepatitis C Agents

Amidate Prodrugs of Deoxythreosyl Nucleoside Phosphonates as Dual Inhibitors of HIV and HBV Replication

Synthesis of novel 5-amino-thiazolo[4,5-d]pyrimidines as E. coli and S. aureus SecA inhibitors

Biopharmaceutical profiling of a pyrido[4,3-d] pyrimidine compound library

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