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The Role of Proteolysis in Amyloidosis

International journal of molecular sciences, 2022-12, Vol.24 (1), p.699

2022

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Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

Nature communications, 2021-03, Vol.12 (1), p.1693-1693, Article 1693

2021

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Probing prothrombin structure by limited proteolysis

Scientific reports, 2019-04, Vol.9 (1), p.6125-6125, Article 6125

2019

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A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca2+ Uptake Machinery of Skeletal Muscle

Molecular cell, 2016-11, Vol.64 (4), p.760-773

2016

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Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC

International journal of molecular sciences, 2021-06, Vol.22 (11), p.6008

2021

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Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation

Scientific reports, 2022-06, Vol.12 (1), p.9880-9880, Article 9880

2022

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Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity

Scientific reports, 2019-01, Vol.9 (1), p.300-300, Article 300

2019

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Sperm Cholesterol Content Modifies Sperm Function and TRPV1-Mediated Sperm Migration

International journal of molecular sciences, 2021-03, Vol.22 (6), p.3126

2021

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Von Willebrand Factor Multimers and the Relaxation Response: A One-Year Study

Entropy (Basel, Switzerland), 2021-04, Vol.23 (4), p.447

2021

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Preliminary Discovery of Small Molecule Inhibitors of Epidermal Growth Factor Receptor (EGFR) That Bind to the Extracellular Domain

Cancers, 2022-07, Vol.14 (15), p.3647

2022

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Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch

Scientific reports, 2017-05, Vol.7 (1), p.1714-14, Article 1714

2017

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A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules

Computational and structural biotechnology journal, 2021-01, Vol.19, p.5622-5636

2021

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NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model

Biomedicines, 2022-01, Vol.10 (1), p.102

2022

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From haemadin to haemanorm: Synthesis and characterization of full‐length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent thrombin inhibitor (haemanorm)

Protein science, 2023-12, Vol.32 (12), p.e4825-e4825

2023

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Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant–anticoagulant equilibrium toward thrombosis

The Journal of biological chemistry, 2017-09, Vol.292 (37), p.15161-15179

2017

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Endocrine Disruption of Androgenic Activity by Perfluoroalkyl Substances: Clinical and Experimental Evidence

The journal of clinical endocrinology and metabolism, 2019-04, Vol.104 (4), p.1259-1271

2019

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Interplay between conformational selection and zymogen activation

Scientific reports, 2018-03, Vol.8 (1), p.4080-10, Article 4080

2018

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A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue

Bioorganic & medicinal chemistry, 2023-11, Vol.95, p.117499-117499, Article 117499

2023

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Endocrine disruption of vitamin D activity by perfluoro-octanoic acid (PFOA)

Scientific reports, 2020-10, Vol.10 (1), p.16789, Article 16789

2020

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The role of high molecular weight hyaluronic acid in mucoadhesion on an ocular surface model

Journal of the mechanical behavior of biomedical materials, 2023-07, Vol.143, p.105908-105908, Article 105908

2023

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Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells

Biochemical journal, 2017-11, Vol.474 (22), p.3767-3781

2017

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Molecular mapping of α-thrombin (αT)/β2-glycoprotein I (β2GpI) interaction reveals how β2GpI affects αT functions

Biochemical journal, 2016-12, Vol.473 (24), p.4629-4650

2016

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Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2

European journal of pharmaceutical sciences, 2023-08, Vol.187, p.106489-106489, Article 106489

2023

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Noncoded amino acids in protein engineering: Structure–activity relationship studies of hirudin–thrombin interaction

Biotechnology and applied biochemistry, 2018-01, Vol.65 (1), p.69-80

2018

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Thrombin inhibits the anti-myeloperoxidase and ferroxidase functions of ceruloplasmin: relevance in rheumatoid arthritis

Free radical biology & medicine, 2015-09, Vol.86, p.279-294

2015

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The Role of Proteolysis in Amyloidosis

Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

Probing prothrombin structure by limited proteolysis

A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca2+ Uptake Machinery of Skeletal Muscle

Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC

Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation

Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity

Sperm Cholesterol Content Modifies Sperm Function and TRPV1-Mediated Sperm Migration

Von Willebrand Factor Multimers and the Relaxation Response: A One-Year Study

Preliminary Discovery of Small Molecule Inhibitors of Epidermal Growth Factor Receptor (EGFR) That Bind to the Extracellular Domain

Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch

A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules

NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model

From haemadin to haemanorm: Synthesis and characterization of full‐length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent thrombin inhibitor (haemanorm)

Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant–anticoagulant equilibrium toward thrombosis

Endocrine Disruption of Androgenic Activity by Perfluoroalkyl Substances: Clinical and Experimental Evidence

Interplay between conformational selection and zymogen activation

A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue

Endocrine disruption of vitamin D activity by perfluoro-octanoic acid (PFOA)

The role of high molecular weight hyaluronic acid in mucoadhesion on an ocular surface model

Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells

Molecular mapping of α-thrombin (αT)/β2-glycoprotein I (β2GpI) interaction reveals how β2GpI affects αT functions

Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2

Noncoded amino acids in protein engineering: Structure–activity relationship studies of hirudin–thrombin interaction

Thrombin inhibits the anti-myeloperoxidase and ferroxidase functions of ceruloplasmin: relevance in rheumatoid arthritis

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