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Ultrasound modulates ion channel currents

Scientific reports, 2016-04, Vol.6 (1), p.24170-24170, Article 24170

2016

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Cellular elements for seeing in the dark: voltage-dependent conductances in cockroach photoreceptors

BMC neuroscience, 2012-08, Vol.13 (1), p.93-93, Article 93

2012

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Structure-activity relationship studies of four novel 4-aminopyridine K + channel blockers

Scientific reports, 2020-01, Vol.10 (1), p.52-52, Article 52

2020

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Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial

PloS one, 2017-07, Vol.12 (7), p.e0180762-e0180762

2017

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Ion channels as drug targets in central nervous system disorders

Current medicinal chemistry, 2013-04, Vol.20 (10), p.1241

2013

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Effect of nitric oxide-cyclic GMP-K + channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom

Canadian journal of physiology and pharmacology, 2023-01, Vol.101 (1), p.41

2023

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Potassium Channel Blockade Enhances Atrial Fibrillation-Selective Antiarrhythmic Effects of Optimized State-Dependent Sodium Channel Blockade

Circulation (New York, N.Y.), 2015-12, Vol.132 (23), p.2203-2211

2015

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Citral inhibits the nociception in the rat formalin test: effect of metformin and blockers of opioid receptor and the NO-cGMP-K + channel pathway

Canadian journal of physiology and pharmacology, 2022-04, Vol.100 (4), p.306

2022

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Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

PloS one, 2020-11, Vol.15 (11), p.e0234946

2020

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Atrial-selective K + channel blockers: potential antiarrhythmic drugs in atrial fibrillation?

Canadian journal of physiology and pharmacology, 2017-11, Vol.95 (11), p.1313

Ravens, Ursula

2017

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Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

Clinical immunology (Orlando, Fla.), 2017-07, Vol.180, p.45-57

2017

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Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Circulation (New York, N.Y.), 2014-01, Vol.129 (4), p.430-440

2014

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Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

Nature, 2006-04, Vol.440 (7086), p.959-962

2006

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The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

Drug discovery today, 2009-11, Vol.14 (21), p.1011-1020

2009

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Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes

Marine drugs, 2020-08, Vol.18 (8), p.425

2020

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A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

PloS one, 2013-11, Vol.8 (11), p.e78712

2013

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Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

Scientific reports, 2020-03, Vol.10 (1), p.4476, Article 4476

2020

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Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

PloS one, 2020-11, Vol.15 (11), p.e0233815-e0233815

2020

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Combining mKate2-Kv1.3 Channel and Atto488-Hongotoxin for the Studies of Peptide Pore Blockers on Living Eukaryotic Cells

Toxins, 2022-12, Vol.14 (12), p.858

2022

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Chronic Stress Causes Amygdala Hyperexcitability in Rodents

Biological psychiatry (1969), 2010-06, Vol.67 (12), p.1128-1136

2010

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High-throughput electrophysiological assays for voltage gated ion channels using SyncroPatch 768PE

PloS one, 2017-07, Vol.12 (7), p.e0180154-e0180154

2017

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Alternative Targets for Modulators of Mitochondrial Potassium Channels

Molecules (Basel, Switzerland), 2022-01, Vol.27 (1), p.299

2022

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The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels

Scientific reports, 2016-08, Vol.6 (1), p.32121, Article 32121

2016

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Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

Pain (Amsterdam), 2013-03, Vol.154 (3), p.434

2013

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Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block

PloS one, 2016-12, Vol.11 (12), p.e0163619-e0163619

2016

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Ultrasound modulates ion channel currents

Cellular elements for seeing in the dark: voltage-dependent conductances in cockroach photoreceptors

Structure-activity relationship studies of four novel 4-aminopyridine K + channel blockers

Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial

Ion channels as drug targets in central nervous system disorders

Effect of nitric oxide-cyclic GMP-K + channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom

Potassium Channel Blockade Enhances Atrial Fibrillation-Selective Antiarrhythmic Effects of Optimized State-Dependent Sodium Channel Blockade

Citral inhibits the nociception in the rat formalin test: effect of metformin and blockers of opioid receptor and the NO-cGMP-K + channel pathway

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Atrial-selective K + channel blockers: potential antiarrhythmic drugs in atrial fibrillation?

Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes

A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ

Combining mKate2-Kv1.3 Channel and Atto488-Hongotoxin for the Studies of Peptide Pore Blockers on Living Eukaryotic Cells

Chronic Stress Causes Amygdala Hyperexcitability in Rodents

High-throughput electrophysiological assays for voltage gated ion channels using SyncroPatch 768PE

Alternative Targets for Modulators of Mitochondrial Potassium Channels

The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels

Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block

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