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Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia

Physiological reviews, 2014-04, Vol.94 (2), p.609-653

2014

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Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

Cardiovascular research, 2014-07, Vol.103 (1), p.156-167

2014

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Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (34), p.E8077-E8085

2018

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Single-copy insertion of transgenes in Caenorhabditis elegans

Nature genetics, 2008-11, Vol.40 (11), p.1375-1383

2008

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Cardiac SK channels: Friend or foe?

Heart rhythm, 2015-05, Vol.12 (5), p.1016-1017

Grunnet, Morten, PhD, Dr Sci

2015

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Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

PloS one, 2015-06, Vol.10 (6), p.e0131432

2015

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Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses

Heart rhythm, 2015-04, Vol.12 (4), p.825-835

2015

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Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Circulation (New York, N.Y.), 2014-01, Vol.129 (4), p.430-440

2014

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Structural insight into concealed long QT type 1

Heart rhythm, 2014-03, Vol.11 (3), p.469-470

Grunnet, Morten, PhD, DrSci

2014

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The KCNQ1 Potassium Channel: From Gene to Physiological Function

Physiology (Bethesda, Md.), 2005-12, Vol.20 (6), p.408-416

2005

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Pharmacological treatment of atrial fibrillation: What does it take?

Heart rhythm, 2011-12, Vol.8 (12), p.1940-1941

Grunnet, Morten, PhD

2011

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Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

American journal of human genetics, 2010-06, Vol.86 (6), p.872-880

2010

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The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

Frontiers in pharmacology, 2020-02, Vol.11

2020

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Effects on Atrial Fibrillation in Aged Hypertensive Rats by Ca2+-Activated K+ Channel Inhibition

Hypertension (Dallas, Tex. 1979), 2011-06, Vol.57 (6), p.1129-1135

2011

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Inhibition of Small-Conductance Ca2+-Activated K+ Channels Terminates and Protects Against Atrial Fibrillation

Circulation. Arrhythmia and electrophysiology, 2010-08, Vol.3 (4), p.380-390

2010

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The Duration of Pacing-induced Atrial Fibrillation Is Reduced in Vivo by Inhibition of Small Conductance Ca2+-activated K+ Channels

Journal of cardiovascular pharmacology, 2011-06, Vol.57 (6), p.672-681

2011

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Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel

Journal of cardiovascular electrophysiology, 2010-01, Vol.21 (1), p.107-115

2010

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Energetic performance is improved by specific activation of K+ fluxes through KCa channels in heart mitochondria

Biochimica et biophysica acta. Bioenergetics, 2010-01, Vol.1797 (1), p.71-80

2010

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Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

Frontiers in pharmacology, 2020-05, Vol.11, p.610-610

2020

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Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

Pflügers Archiv, 2009-11, Vol.459 (1), p.11-23

2009

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G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

Cardiovascular research, 2014-01, Vol.101 (1), p.175-184

2014

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The Small Molecule NS11021 Is a Potent and Specific Activator of Ca2+-Activated Big-Conductance K+ Channels

Molecular pharmacology, 2007-10, Vol.72 (4), p.1033-1044

2007

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Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats

Biochemical pharmacology, 2013-11, Vol.86 (10), p.1487-1496

2013

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Flecainide Provocation Reveals Concealed Brugada Syndrome in a Long QT Syndrome Family With a Novel L1786Q Mutation in SCN5A

Circulation Journal, 2014, Vol.78(5), pp.1136-1143

2014

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Activation of big conductance Ca2+-activated K+ channels (BK) protects the heart against ischemia–reperfusion injury

Pflügers Archiv, 2009-03, Vol.457 (5), p.979-988

2009

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Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia

Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death

Single-copy insertion of transgenes in Caenorhabditis elegans

Cardiac SK channels: Friend or foe?

Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses

Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Structural insight into concealed long QT type 1

The KCNQ1 Potassium Channel: From Gene to Physiological Function

Pharmacological treatment of atrial fibrillation: What does it take?

Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

Effects on Atrial Fibrillation in Aged Hypertensive Rats by Ca2+-Activated K+ Channel Inhibition

Inhibition of Small-Conductance Ca2+-Activated K+ Channels Terminates and Protects Against Atrial Fibrillation

The Duration of Pacing-induced Atrial Fibrillation Is Reduced in Vivo by Inhibition of Small Conductance Ca2+-activated K+ Channels

Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel

Energetic performance is improved by specific activation of K+ fluxes through KCa channels in heart mitochondria

Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

The Small Molecule NS11021 Is a Potent and Specific Activator of Ca2+-Activated Big-Conductance K+ Channels

Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats

Flecainide Provocation Reveals Concealed Brugada Syndrome in a Long QT Syndrome Family With a Novel L1786Q Mutation in SCN5A

Activation of big conductance Ca2+-activated K+ channels (BK) protects the heart against ischemia–reperfusion injury

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