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Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Molecules (Basel, Switzerland), 2017-07, Vol.22 (7), p.1192

2017

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Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults

Cochrane database of systematic reviews, 2017-08, Vol.8 (9), p.CD012763

2017

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Cholinesterase inhibitors as Alzheimer's therapeutics (Review)

Molecular medicine reports, 2019-08, Vol.20 (2), p.1479-1487

Sharma, Kamlesh

2019

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Natural cholinesterase inhibitors from marine organisms

Natural product reports, 2019-08, Vol.36 (8), p.153-192

2019

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Cholinesterases and the fine line between poison and remedy

Biochemical pharmacology, 2018-07, Vol.153, p.205-216

2018

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Metformin – a Future Therapy for Neurodegenerative Diseases: Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla

Pharmaceutical research, 2017-12, Vol.34 (12), p.2614-2627

2017

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Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors

Archiv der Pharmazie (Weinheim), 2022-01, Vol.355 (1), p.e2100242-n/a

2022

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Cholinesterase targeting by polyphenols: A therapeutic approach for the treatment of Alzheimer’s disease

CNS neuroscience & therapeutics, 2018-09, Vol.24 (9), p.753-762

2018

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An update on the utility and safety of cholinesterase inhibitors for the treatment of Alzheimer's disease

Expert opinion on drug safety, 2020-02, Vol.19 (2), p.147-157

2020

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Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease

European journal of medicinal chemistry, 2016-06, Vol.116, p.200-209

2016

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Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives

International journal of biological macromolecules, 2021-02, Vol.170, p.1-12

2021

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Structure-Based Design and Optimization of Multitarget-Directed 2H‑Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

Journal of medicinal chemistry, 2015-07, Vol.58 (14), p.5561

2015

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Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection

Journal of medicinal chemistry, 2021-05, Vol.64 (10), p.6856-6876

2021

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Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.10030-10044

2020

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Cognitive symptoms of Alzheimer's disease: clinical management and prevention

BMJ (Online), 2019-12, Vol.367, p.l6217

2019

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Effect of acetylcholinesterase inhibitors on post-stroke cognitive impairment and vascular dementia: A meta-analysis

PloS one, 2020-02, Vol.15 (2), p.e0227820-e0227820

2020

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Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

European journal of medicinal chemistry, 2014-06, Vol.80, p.543-561

2014

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Design, synthesis, and AChE inhibitory activity of new benzothiazole–piperazines

Bioorganic & medicinal chemistry letters, 2016-11, Vol.26 (22), p.5387-5394

2016

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Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects

Biomedicine & pharmacotherapy, 2018-05, Vol.101, p.860-870

2018

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Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2022-02, Vol.229, p.114044-114044, Article 114044

2022

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Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors

Bioorganic chemistry, 2019-05, Vol.86, p.420-427

2019

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Discovery, Biological Evaluation, and Crystal Structure of a Novel Nanomolar Selective Butyrylcholinesterase Inhibitor

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.8167-8179

2014

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MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer’s Disease

Neurochemical research, 2024-06, Vol.49 (6), p.1518-1528

2024

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Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer’s Disease Based on the Fusion of Donepezil and Ebselen

Journal of medicinal chemistry, 2013-11, Vol.56 (22), p.9089-9099

2013

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Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults

Cholinesterase inhibitors as Alzheimer's therapeutics (Review)

Natural cholinesterase inhibitors from marine organisms

Cholinesterases and the fine line between poison and remedy

Metformin – a Future Therapy for Neurodegenerative Diseases: Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla

Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

Cholinesterase targeting by polyphenols: A therapeutic approach for the treatment of Alzheimer’s disease

An update on the utility and safety of cholinesterase inhibitors for the treatment of Alzheimer's disease

Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease

Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives

Structure-Based Design and Optimization of Multitarget-Directed 2H‑Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection

Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor

Cognitive symptoms of Alzheimer's disease: clinical management and prevention

Effect of acetylcholinesterase inhibitors on post-stroke cognitive impairment and vascular dementia: A meta-analysis

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

Design, synthesis, and AChE inhibitory activity of new benzothiazole–piperazines

Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects

Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease

Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors

Discovery, Biological Evaluation, and Crystal Structure of a Novel Nanomolar Selective Butyrylcholinesterase Inhibitor

MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer’s Disease

Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer’s Disease Based on the Fusion of Donepezil and Ebselen

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