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Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds

Molecules (Basel, Switzerland), 2018-01, Vol.23 (2), p.250

2018

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Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs

Biochemical pharmacology, 2017-11, Vol.143, p.39-52

2017

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A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)

Molecules (Basel, Switzerland), 2022-01, Vol.27 (3), p.958

2022

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Structure-Based Design and Optimization of Multitarget-Directed 2H‑Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

Journal of medicinal chemistry, 2015-07, Vol.58 (14), p.5561

2015

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First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease

Molecules (Basel, Switzerland), 2021-08, Vol.26 (17), p.5208

2021

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Peaks and widths of radio-frequency spectra: An analysis of the phase diagram of ultra-cold Fermi gases

Results in physics, 2024-02, Vol.57, p.107358, Article 107358

2024

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Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif

Molecules (Basel, Switzerland), 2016-03, Vol.21 (3), p.362-362

2016

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Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer's Disease

Molecules (Basel, Switzerland), 2020-12, Vol.25 (23), p.5773

2020

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Abstract 1122‐000047: Machine Learning to Predict Stroke Outcomes after Mechanical Thrombectomy

Stroke: vascular and interventional neurology, 2021-11, Vol.1 (S1)

2021

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Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity

Molecules (Basel, Switzerland), 2018-06, Vol.23 (7), p.1544

2018

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A twenty-year journey exploring coumarin-based derivatives as bioactive molecules

Frontiers in chemistry, 2022-10, Vol.10, p.1002547-1002547

2022

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Discovery, Biological Evaluation, and Structure–Activity and −Selectivity Relationships of 6′-Substituted (E)‑2-(Benzofuran-3(2H)‑ylidene)‑N‑methylacetamides, a Novel Class of Potent and Selective Monoamine Oxidase Inhibitors

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2651-2664

2013

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Causes of mortality in early infantile epileptic encephalopathy: A systematic review

Epilepsy & behavior, 2018-08, Vol.85, p.32-36

2018

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A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics

Antioxidants, 2024-01, Vol.13 (1), p.133

2024

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Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential

Molecules (Basel, Switzerland), 2021-01, Vol.26 (2), p.359

2021

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Comparative analysis between 1-D, 2-D and 3-D carotid web quantification

Journal of neurointerventional surgery, 2023-02, Vol.15 (2), p.153

2023

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Differences in the Cortical Structure of the Whole Fibula and Tibia Between Long-Distance Runners and Untrained Controls. Toward a Wider Conception of the Biomechanical Regulation of Cortical Bone Structure

Frontiers in endocrinology (Lausanne), 2019-11, Vol.10, p.833-833

2019

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Homodimeric Bis-Quaternary Heterocyclic Ammonium Salts as Potent Acetyl- and Butyrylcholinesterase Inhibitors: A Systematic Investigation of the Influence of Linker and Cationic Heads over Affinity and Selectivity

Journal of medicinal chemistry, 2011-04, Vol.54 (8), p.2627-2645

2011

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4-Hydroxycoumarins as Michael donors in asymmetric routes to polycyclic coumarins (microreview)

Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2018-04, Vol.54 (4), p.394-396

2018

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Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors

European journal of medicinal chemistry, 2019-01, Vol.161, p.292-309

2019

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Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase

Bioorganic & medicinal chemistry, 2013-01, Vol.21 (1), p.146-152

2013

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Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5848-5852

2007

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1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1

European journal of medicinal chemistry, 2019-01, Vol.161, p.433-444

2019

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Noncontrast Computed Tomography e-Stroke Infarct Volume Is Similar to RAPID Computed Tomography Perfusion in Estimating Postreperfusion Infarct Volumes

Stroke (1970), 2021-02, Vol.52 (2), p.634-641

2021

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Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies

Journal of medicinal chemistry, 2022-03, Vol.65 (5), p.3962-3977

2022

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Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds

Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs

A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)

Structure-Based Design and Optimization of Multitarget-Directed 2H‑Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease

Peaks and widths of radio-frequency spectra: An analysis of the phase diagram of ultra-cold Fermi gases

Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif

Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer's Disease

Abstract 1122‐000047: Machine Learning to Predict Stroke Outcomes after Mechanical Thrombectomy

Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity

A twenty-year journey exploring coumarin-based derivatives as bioactive molecules

Discovery, Biological Evaluation, and Structure–Activity and −Selectivity Relationships of 6′-Substituted (E)‑2-(Benzofuran-3(2H)‑ylidene)‑N‑methylacetamides, a Novel Class of Potent and Selective Monoamine Oxidase Inhibitors

Causes of mortality in early infantile epileptic encephalopathy: A systematic review

A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics

Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential

Comparative analysis between 1-D, 2-D and 3-D carotid web quantification

Differences in the Cortical Structure of the Whole Fibula and Tibia Between Long-Distance Runners and Untrained Controls. Toward a Wider Conception of the Biomechanical Regulation of Cortical Bone Structure

Homodimeric Bis-Quaternary Heterocyclic Ammonium Salts as Potent Acetyl- and Butyrylcholinesterase Inhibitors: A Systematic Investigation of the Influence of Linker and Cationic Heads over Affinity and Selectivity

4-Hydroxycoumarins as Michael donors in asymmetric routes to polycyclic coumarins (microreview)

Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors

Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase

Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs

1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1

Noncontrast Computed Tomography e-Stroke Infarct Volume Is Similar to RAPID Computed Tomography Perfusion in Estimating Postreperfusion Infarct Volumes

Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies

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