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New thiazole-2(3H)-thiones containing 4-(3,4,5-trimethoxyphenyl) moiety as anticancer agents

European journal of medicinal chemistry, 2020-01, Vol.185, p.111784, Article 111784

2020

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Discrete and Stereospecific Oligomers Prepared by Sequential and Alternating Single Unit Monomer Insertion

Journal of the American Chemical Society, 2018-10, Vol.140 (41), p.13392-13406

2018

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Synthesis and biological evaluation of 1,2,4‐triazole‐3‐thione and 1,3,4‐oxadiazole‐2‐thione as antimycobacterial agents

Chemical biology & drug design, 2017-08, Vol.90 (2), p.200-209

2017

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Recent advances bioactive 1,2,4-triazole-3-thiones

European journal of medicinal chemistry, 2015-06, Vol.97, p.830-870

2015

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Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

The Journal of experimental medicine, 2017-11, Vol.214 (11), p.3219-3238

2017

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4,5-Diaryl-3H-1,2-dithiole-3-thiones and related compounds as combretastatin A-4/oltipraz hybrids: Synthesis, molecular modelling and evaluation as antiproliferative agents and inhibitors of tubulin

European journal of medicinal chemistry, 2016-10, Vol.122, p.520-529

2016

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Design, Synthesis and Antibacterial Evaluation of 1‐[(1R,2S)‐2‐Fluorocyclopropyl]ciprofloxacin‐1,2,4‐triazole‐5(4H)‐thione Hybrids

Chemistry & biodiversity, 2018-10, Vol.15 (10), p.e1800261-n/a

2018

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Design, synthesis and anticancer activity of new monastrol analogues bearing 1,3,4-oxadiazole moiety

European journal of medicinal chemistry, 2017-09, Vol.138, p.140-151

2017

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Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidin-2(1H)-ones and -thiones, the Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-60 Cells

Chemical and Pharmaceutical Bulletin, 2022/02/01, Vol.70(2), pp.111-119

2022

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Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux

Biochemical and biophysical research communications, 2015-03, Vol.458 (3), p.632-638

2015

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AP39, A Mitochondrially Targeted Hydrogen Sulfide Donor, Exerts Protective Effects in Renal Epithelial Cells Subjected to Oxidative Stress in Vitro and in Acute Renal Injury in Vivo

Shock (Augusta, Ga.), 2016-01, Vol.45 (1), p.88-97

2016

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Oral TNFα Modulation Alters Neutrophil Infiltration, Improves Cognition and Diminishes Tau and Amyloid Pathology in the 3xTgAD Mouse Model

PloS one, 2015-10, Vol.10 (10), p.e0137305

2015

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Heterocyclic-2-thione derivatives of group 10–12 metals: Coordination versatility, activation of C S (thione) bonds and biochemical potential

Coordination chemistry reviews, 2021-08, Vol.441, p.213884, Article 213884

Lobana, Tarlok Singh

2021

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A facile and catalyst-free microwave-promoted method for the synthesis of 3-trifluoromethyl 1,2,4-triazole-5-thiones

Tetrahedron letters, 2023-10, Vol.129, p.154727, Article 154727

2023

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Pharmacological activation of the Nrf2 pathway by 3H-1, 2-dithiole-3-thione is neuroprotective in a mouse model of Alzheimer disease

Behavioural brain research, 2018-01, Vol.336, p.219-226

2018

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Development of 1,3,4-oxadiazole thione based novel anticancer agents: Design, synthesis and in-vitro studies

Biomedicine & pharmacotherapy, 2017-11, Vol.95, p.721-730

2017

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Transdermal Delivery of a Hydrogen Sulphide Donor, ADT-OH Using Aqueous Gel Formulations for the Treatment of Impaired Vascular Function: an Ex Vivo Study

Pharmaceutical research, 2022-02, Vol.39 (2), p.341-352

2022

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Mechanistic Characterization of a 2‑Thioxanthine Myeloperoxidase Inhibitor and Selectivity Assessment Utilizing Click Chemistry–Activity-Based Protein Profiling

Biochemistry (Easton), 2013-12, Vol.52 (51), p.9187-9201

2013

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Synthesis of 5-(5-methyl-benzofuran-3-ylmethyl)-3H- [1, 3, 4] oxadiazole-2-thione and investigation of its spectroscopic, reactivity, optoelectronic and drug likeness properties by combined computational and experimental approach

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2018-12, Vol.205, p.95-110

2018

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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

European journal of medicinal chemistry, 2021-12, Vol.226, p.113873-113873, Article 113873

2021

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Heterocyclic-2-thione derivatives of group 10–12 metals: Coordination versatility, activation of CS (thione) bonds and biochemical potential

Coordination chemistry reviews, 2021-08, Vol.441, Article 213884

Lobana, Tarlok Singh

2021

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Discovery of a series of 1,3,4-oxadiazole-2(3H)-thione derivatives containing piperazine skeleton as potential FAK inhibitors

Bioorganic & medicinal chemistry, 2017-05, Vol.25 (9), p.2593-2600

2017

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Discovery of 1‐Hydroxypyridine‐2(1H)‐thione‐6‐carboxylic Acid as a First‐in‐Class Low‐Cytotoxic Nanomolar Metallo β‐Lactamase Inhibitor

ChemMedChem, 2017-06, Vol.12 (11), p.845-849

2017

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3‑Hydroxypyridin-2-thione as Novel Zinc Binding Group for Selective Histone Deacetylase Inhibition

Journal of medicinal chemistry, 2013-05, Vol.56 (9), p.3492-3506

2013

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Synthesis and biological evaluation of β-lapachone-monastrol hybrids as potential anticancer agents

European journal of medicinal chemistry, 2020-10, Vol.203, p.112594-112594, Article 112594

2020

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New thiazole-2(3H)-thiones containing 4-(3,4,5-trimethoxyphenyl) moiety as anticancer agents

Discrete and Stereospecific Oligomers Prepared by Sequential and Alternating Single Unit Monomer Insertion

Synthesis and biological evaluation of 1,2,4‐triazole‐3‐thione and 1,3,4‐oxadiazole‐2‐thione as antimycobacterial agents

Recent advances bioactive 1,2,4-triazole-3-thiones

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

4,5-Diaryl-3H-1,2-dithiole-3-thiones and related compounds as combretastatin A-4/oltipraz hybrids: Synthesis, molecular modelling and evaluation as antiproliferative agents and inhibitors of tubulin

Design, Synthesis and Antibacterial Evaluation of 1‐[(1R,2S)‐2‐Fluorocyclopropyl]ciprofloxacin‐1,2,4‐triazole‐5(4H)‐thione Hybrids

Design, synthesis and anticancer activity of new monastrol analogues bearing 1,3,4-oxadiazole moiety

Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidin-2(1H)-ones and -thiones, the Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-60 Cells

Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux

AP39, A Mitochondrially Targeted Hydrogen Sulfide Donor, Exerts Protective Effects in Renal Epithelial Cells Subjected to Oxidative Stress in Vitro and in Acute Renal Injury in Vivo

Oral TNFα Modulation Alters Neutrophil Infiltration, Improves Cognition and Diminishes Tau and Amyloid Pathology in the 3xTgAD Mouse Model

Heterocyclic-2-thione derivatives of group 10–12 metals: Coordination versatility, activation of C S (thione) bonds and biochemical potential

A facile and catalyst-free microwave-promoted method for the synthesis of 3-trifluoromethyl 1,2,4-triazole-5-thiones

Pharmacological activation of the Nrf2 pathway by 3H-1, 2-dithiole-3-thione is neuroprotective in a mouse model of Alzheimer disease

Development of 1,3,4-oxadiazole thione based novel anticancer agents: Design, synthesis and in-vitro studies

Transdermal Delivery of a Hydrogen Sulphide Donor, ADT-OH Using Aqueous Gel Formulations for the Treatment of Impaired Vascular Function: an Ex Vivo Study

Mechanistic Characterization of a 2‑Thioxanthine Myeloperoxidase Inhibitor and Selectivity Assessment Utilizing Click Chemistry–Activity-Based Protein Profiling

Synthesis of 5-(5-methyl-benzofuran-3-ylmethyl)-3H- [1, 3, 4] oxadiazole-2-thione and investigation of its spectroscopic, reactivity, optoelectronic and drug likeness properties by combined computational and experimental approach

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

Heterocyclic-2-thione derivatives of group 10–12 metals: Coordination versatility, activation of CS (thione) bonds and biochemical potential

Discovery of a series of 1,3,4-oxadiazole-2(3H)-thione derivatives containing piperazine skeleton as potential FAK inhibitors

Discovery of 1‐Hydroxypyridine‐2(1H)‐thione‐6‐carboxylic Acid as a First‐in‐Class Low‐Cytotoxic Nanomolar Metallo β‐Lactamase Inhibitor

3‑Hydroxypyridin-2-thione as Novel Zinc Binding Group for Selective Histone Deacetylase Inhibition

Synthesis and biological evaluation of β-lapachone-monastrol hybrids as potential anticancer agents

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