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Ultra-large library docking for discovering new chemotypes

Nature (London), 2019-02, Vol.566 (7743), p.224-229

2019

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Impaired dopamine signaling in early diabetic retina: Insights from D1R and D4R agonist effects on whole retina responses

Experimental eye research, 2024-10, Vol.247, p.110049, Article 110049

2024

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Dopaminergic Modulation of Risk-Based Decision Making

Neuropsychopharmacology (New York, N.Y.), 2009-02, Vol.34 (3), p.681-697

2009

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The Impact of Selective Dopamine D2, D3 and D4 Ligands on the Rat Gambling Task

PloS one, 2015-09, Vol.10 (9), p.e0136267-e0136267

2015

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Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex

The Journal of neuroscience, 2014-03, Vol.34 (10), p.3706-3718

2014

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Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms

The Journal of neuroscience, 2013-10, Vol.33 (43), p.16853-16864

2013

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Characterizing fucoxanthin as a selective dopamine D 3 /D 4 receptor agonist: Relevance to Parkinson's disease

Chemico-biological interactions, 2019-09, Vol.310, p.108757

2019

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A Selective Role for Dopamine D4 Receptors in Modulating Reward Expectancy in a Rodent Slot Machine Task

Biological psychiatry (1969), 2014-05, Vol.75 (10), p.817-824

2014

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Dopaminergic Regulation of Inhibitory and Excitatory Transmission in the Basolateral Amygdala-Prefrontal Cortical Pathway

The Journal of neuroscience, 2007-02, Vol.27 (8), p.2045-2057

2007

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Intravitreally-administered dopamine D2-like (and D4), but not D1-like, receptor agonists reduce form-deprivation myopia in tree shrews

Visual neuroscience, 2017, Vol.34, p.E003-E003, Article E003

2017

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The dopamine D1 receptor agonist SKF-82958 effectively increases eye blinking count in common marmosets

Behavioural brain research, 2016-03, Vol.300, p.25-30

2016

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In Vitro and In Vivo Characterization of the Alkaloid Nuciferine

PloS one, 2016-03, Vol.11 (3), p.e0150602

2016

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Neurochemical arguments for the use of dopamine D 4 receptor stimulation to improve cognitive impairment associated with schizophrenia

Pharmacology, biochemistry and behavior, 2017-06, Vol.157, p.16-23

2017

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Dopamine D1 versus D4 Receptors Differentially Modulate the Encoding of Salient versus Nonsalient Emotional Information in the Medial Prefrontal Cortex

The Journal of neuroscience, 2009-04, Vol.29 (15), p.4836-4845

2009

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Effects of selective dopaminergic compounds on a delay-discounting task

Behavioural pharmacology, 2011-08, Vol.22 (4), p.300-311

2011

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Role of dopamine D4 receptors in copulatory behavior: Studies with selective D4 agonists and antagonists in male rats

Pharmacology, biochemistry and behavior, 2015-10, Vol.137, p.110-118

2015

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Activation of dopamine D4 receptors within the anterior cingulate cortex enhances the erroneous expectation of reward on a rat slot machine task

Neuropharmacology, 2016-06, Vol.105, p.186-195

2016

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Novel azulene derivatives for the treatment of erectile dysfunction

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (23), p.7151-7154

2012

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The agranular and granular insula differentially contribute to gambling-like behavior on a rat slot machine task: effects of inactivation and local infusion of a dopamine D4 agonist on reward expectancy

Psychopharmacology, 2016-09, Vol.233 (17), p.3135-3147

2016

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Structure and dynamics of DRD4 bound to an agonist and an antagonist using in silico approaches

Proteins, structure, function, and bioinformatics, 2015-05, Vol.83 (5), p.867-880

2015

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WAY-100635 is a potent dopamine D4 receptor agonist

Psychopharmacologia, 2006-10, Vol.188 (2), p.244-251

2006

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New Pyridobenzoxazepine Derivatives Derived from 5-(4-Methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine (JL13): Chemical Synthesis and Pharmacological Evaluation

Journal of medicinal chemistry, 2012-02, Vol.55 (4), p.1572-1582

2012

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Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands

Bioorganic & medicinal chemistry, 2013-06, Vol.21 (11), p.2988-2998

2013

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Aberrant dopamine D2-like receptor function in a rodent model of schizophrenia

The Journal of pharmacology and experimental therapeutics, 2012-11, Vol.343 (2), p.288-295

2012

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Elucidating the role of D4 receptors in mediating attributions of salience to incentive stimuli on Pavlovian conditioned approach and conditioned reinforcement paradigms

Behavioural brain research, 2016-10, Vol.312, p.55-63

2016

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Ultra-large library docking for discovering new chemotypes

Impaired dopamine signaling in early diabetic retina: Insights from D1R and D4R agonist effects on whole retina responses

Dopaminergic Modulation of Risk-Based Decision Making

The Impact of Selective Dopamine D2, D3 and D4 Ligands on the Rat Gambling Task

Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex

Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms

Characterizing fucoxanthin as a selective dopamine D 3 /D 4 receptor agonist: Relevance to Parkinson's disease

A Selective Role for Dopamine D4 Receptors in Modulating Reward Expectancy in a Rodent Slot Machine Task

Dopaminergic Regulation of Inhibitory and Excitatory Transmission in the Basolateral Amygdala-Prefrontal Cortical Pathway

Intravitreally-administered dopamine D2-like (and D4), but not D1-like, receptor agonists reduce form-deprivation myopia in tree shrews

The dopamine D1 receptor agonist SKF-82958 effectively increases eye blinking count in common marmosets

In Vitro and In Vivo Characterization of the Alkaloid Nuciferine

Neurochemical arguments for the use of dopamine D 4 receptor stimulation to improve cognitive impairment associated with schizophrenia

Dopamine D1 versus D4 Receptors Differentially Modulate the Encoding of Salient versus Nonsalient Emotional Information in the Medial Prefrontal Cortex

Effects of selective dopaminergic compounds on a delay-discounting task

Role of dopamine D4 receptors in copulatory behavior: Studies with selective D4 agonists and antagonists in male rats

Activation of dopamine D4 receptors within the anterior cingulate cortex enhances the erroneous expectation of reward on a rat slot machine task

Novel azulene derivatives for the treatment of erectile dysfunction

The agranular and granular insula differentially contribute to gambling-like behavior on a rat slot machine task: effects of inactivation and local infusion of a dopamine D4 agonist on reward expectancy

Structure and dynamics of DRD4 bound to an agonist and an antagonist using in silico approaches

WAY-100635 is a potent dopamine D4 receptor agonist

New Pyridobenzoxazepine Derivatives Derived from 5-(4-Methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine (JL13): Chemical Synthesis and Pharmacological Evaluation

Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands

Aberrant dopamine D2-like receptor function in a rodent model of schizophrenia

Elucidating the role of D4 receptors in mediating attributions of salience to incentive stimuli on Pavlovian conditioned approach and conditioned reinforcement paradigms

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