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Structural Insights into the Atomistic Mechanisms of Action of Small Molecule Inhibitors Targeting the KCa3.1 Channel Pore

Molecular pharmacology, 2017-04, Vol.91 (4), p.392-402

2017

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Inhibition of platelet aggregation by activation of platelet intermediate conductance Ca 2+ -activated potassium channels

Journal of thrombosis and haemostasis, 2022-11, Vol.20 (11), p.2587

2022

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Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block

PloS one, 2020-11, Vol.15 (11), p.e0241362-e0241362

2020

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Aqueous Fraction from Hibiscus sabdariffa Relaxes Mesenteric Arteries of Normotensive and Hypertensive Rats through Calcium Current Reduction and Possibly Potassium Channels Modulation

Nutrients, 2020-06, Vol.12 (6), p.1782-1782

2020

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Mitochondrial K+ channels and their implications for disease mechanisms

Pharmacology & therapeutics (Oxford), 2021-11, Vol.227, p.107874-107874, Article 107874

2021

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The inhibitory effects of pimozide, an antipsychotic drug, on voltage-gated K+ channels in rabbit coronary arterial smooth muscle cells

Drug and chemical toxicology (New York, N.Y. 1978), 2023-03, Vol.46 (2), p.271-280

2023

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Therapeutic potential of targeting G protein-gated inwardly rectifying potassium (GIRK) channels in the central nervous system

Pharmacology & therapeutics (Oxford), 2021-07, Vol.223, p.107808-107808, Article 107808

2021

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Flavonoids as new regulators of mitochondrial potassium channels: contribution to cardioprotection

Journal of pharmacy and pharmacology, 2023-04, Vol.75 (4), p.466-481

2023

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Mechanisms for Ductus Arteriosus Closure

Seminars in perinatology, 2012-04, Vol.36 (2), p.92-97

2012

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Dromedary immune response and specific Kv2.1 antibody generation using a specific immunization approach

International journal of biological macromolecules, 2016-12, Vol.93 (Pt A), p.167-171

2016

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Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress

Alcohol, clinical & experimental research, 2023-01, Vol.47 (1), p.87-94

2023

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The effect of AUT00206, a Kv3 potassium channel modulator, on dopamine synthesis capacity and the reliability of [18F]-FDOPA imaging in schizophrenia

Journal of psychopharmacology (Oxford), 2022-09, Vol.36 (9), p.1061-1069

2022

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Propofol inhibits carbachol‐induced chloride secretion by directly targeting the basolateral K+ channel in rat ileum epithelium

Neurogastroenterology and motility, 2017-02, Vol.29 (2), p.n/a

2017

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Effect of the SK/IK channel modulator 4,5‐dichloro‐1,3‐diethyl‐1,3‐dihydro‐benzoimidazol‐2‐one (NS4591) on contractile force in rat, pig and human detrusor smooth muscle

BJU international, 2011-09, Vol.108 (5), p.771-777

2011

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Ultrasound modulates ion channel currents

Scientific reports, 2016-04, Vol.6 (1), p.24170-24170, Article 24170

2016

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Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2023-06, Vol.378 (1879), p.20220165

2023

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Neurotoxins and pore forming toxins in sea anemones: Potential candidates for new drug development

Histology and histopathology, 2023-01, Vol.38 (1), p.9

2023

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Overexpression of KCNN4 channels in principal neurons produces an anti-seizure effect without reducing their coding ability

Gene therapy, 2024-03, Vol.31 (3-4), p.144-153

2024

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What do we not know about mitochondrial potassium channels?

Biochimica et biophysica acta, 2016-08, Vol.1857 (8), p.1247-1257

2016

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SK Channels Regulate Resting Properties and Signaling Reliability of a Developing Fast-Spiking Neuron

The Journal of neuroscience, 2017-11, Vol.37 (44), p.10738-10747

2017

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Human leukocyte antigen F-associated transcript 10 regulates the I Ks potassium channel by competing for Kv7.1 ubiquitination

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2023-06, Vol.378 (1879), p.20220167

2023

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Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism

Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6300), p.664-669

2016

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Pathways involved in the human vascular Tetrabromobisphenol A response: Calcium and potassium channels and nitric oxide donors

Toxicology (Amsterdam), 2022-03, Vol.470, p.153158-153158, Article 153158

2022

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Cellular elements for seeing in the dark: voltage-dependent conductances in cockroach photoreceptors

BMC neuroscience, 2012-08, Vol.13 (1), p.93-93, Article 93

2012

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Discovery and synthesis of tetrahydroindolone derived semicarbazones as selective Kv1.5 blockers

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (22), p.5859-5863

2006

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Structural Insights into the Atomistic Mechanisms of Action of Small Molecule Inhibitors Targeting the KCa3.1 Channel Pore

Inhibition of platelet aggregation by activation of platelet intermediate conductance Ca 2+ -activated potassium channels

Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block

Aqueous Fraction from Hibiscus sabdariffa Relaxes Mesenteric Arteries of Normotensive and Hypertensive Rats through Calcium Current Reduction and Possibly Potassium Channels Modulation

Mitochondrial K+ channels and their implications for disease mechanisms

The inhibitory effects of pimozide, an antipsychotic drug, on voltage-gated K+ channels in rabbit coronary arterial smooth muscle cells

Therapeutic potential of targeting G protein-gated inwardly rectifying potassium (GIRK) channels in the central nervous system

Flavonoids as new regulators of mitochondrial potassium channels: contribution to cardioprotection

Mechanisms for Ductus Arteriosus Closure

Dromedary immune response and specific Kv2.1 antibody generation using a specific immunization approach

Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress

The effect of AUT00206, a Kv3 potassium channel modulator, on dopamine synthesis capacity and the reliability of [18F]-FDOPA imaging in schizophrenia

Propofol inhibits carbachol‐induced chloride secretion by directly targeting the basolateral K+ channel in rat ileum epithelium

Effect of the SK/IK channel modulator 4,5‐dichloro‐1,3‐diethyl‐1,3‐dihydro‐benzoimidazol‐2‐one (NS4591) on contractile force in rat, pig and human detrusor smooth muscle

Ultrasound modulates ion channel currents

Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome

Neurotoxins and pore forming toxins in sea anemones: Potential candidates for new drug development

Overexpression of KCNN4 channels in principal neurons produces an anti-seizure effect without reducing their coding ability

What do we not know about mitochondrial potassium channels?

SK Channels Regulate Resting Properties and Signaling Reliability of a Developing Fast-Spiking Neuron

Human leukocyte antigen F-associated transcript 10 regulates the I Ks potassium channel by competing for Kv7.1 ubiquitination

Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism

Pathways involved in the human vascular Tetrabromobisphenol A response: Calcium and potassium channels and nitric oxide donors

Cellular elements for seeing in the dark: voltage-dependent conductances in cockroach photoreceptors

Discovery and synthesis of tetrahydroindolone derived semicarbazones as selective Kv1.5 blockers

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