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Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations

The Journal of clinical investigation, 2015-05, Vol.125 (5), p.1901-1912

2015

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Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (29), p.11698-11703

2013

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Capsaicin augments synaptic transmission in the rat medial preoptic nucleus

Brain research, 2005-05, Vol.1043 (1), p.1-11

2005

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Protein kinase C as a tumor suppressor

Seminars in cancer biology, 2018-02, Vol.48, p.18-26

Newton, Alexandra C

2018

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Protein kinase C pharmacology: refining the toolbox

Biochemical journal, 2013-06, Vol.452 (2), p.195-209

2013

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Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes

Nature communications, 2017-02, Vol.8 (1), p.6-6, Article 6

2017

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New phorbol ester derivatives as potent anti-HIV agents

Bioorganic & medicinal chemistry letters, 2021-10, Vol.50, p.128319-128319, Article 128319

2021

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Control of ADAM17 activity by regulation of its cellular localisation

Scientific reports, 2016-10, Vol.6 (1), p.35067-35067, Article 35067

2016

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Tigliane-Type Diterpene Esters from the Fruits of Shirakiopsis indica and Their Anti-HIV Activity

Journal of natural products (Washington, D.C.), 2022-11, Vol.85 (11), p.2687-2693

2022

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Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro

Nature chemistry, 2012-09, Vol.4 (9), p.705

2012

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The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation

Nucleic acids research, 2013-01, Vol.41 (1), p.277

2013

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QuaNCAT: quantitating proteome dynamics in primary cells

Nature methods, 2013-04, Vol.10 (4), p.343

2013

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Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function

Leukemia, 2019-12, Vol.33 (12), p.2962-2966

2019

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Protein kinase C and other diacylglycerol effectors in cancer

Nature reviews. Cancer, 2007-04, Vol.7 (4), p.281-294

2007

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Molecular dynamics simulation studies on binding of activator and inhibitor to Munc13-1 C1 in the presence of membrane

Journal of biomolecular structure & dynamics, 2022-01, Vol.40 (24), p.14160-14175

2022

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Transient Receptor Potential Vanilloid (TRPV4) channel inhibition: A novel promising approach for the treatment of lung diseases

Biomedicine & pharmacotherapy, 2023-07, Vol.163, p.114861-114861, Article 114861

2023

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Traditional detoxification of Jatropha curcas L. seeds

Journal of ethnopharmacology, 2019-09, Vol.241, p.111970, Article 111970

2019

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Mitoquinone (MitoQ) Inhibits Platelet Activation Steps by Reducing ROS Levels

International journal of molecular sciences, 2020-08, Vol.21 (17), p.6192

2020

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DP from Euphorbia fischeriana S. mediated apoptosis in leukemia cells via the PI3k/Akt signaling pathways

Journal of ethnopharmacology, 2021-10, Vol.279, p.113889-113889, Article 113889

2021

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Synthesis and anti-HIV activities of phorbol derivatives

Chinese journal of natural medicines, 2024-02, Vol.22 (2), p.146-160

2024

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Characterization of Microvesicles Released from Human Red Blood Cells

Cellular physiology and biochemistry, 2016-01, Vol.38 (3), p.1085-1099

2016

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mTOR and S6K1 Mediate Assembly of the Translation Preinitiation Complex through Dynamic Protein Interchange and Ordered Phosphorylation Events

Cell, 2005-11, Vol.123 (4), p.569-580

2005

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12-Deoxyphorbol Esters Induce Growth Arrest and Apoptosis in Human Lung Cancer A549 Cells Via Activation of PKC-δ/PKD/ERK Signaling Pathway

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7579

2020

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4-Deoxyphorbol inhibits HIV-1 infection in synergism with antiretroviral drugs and reactivates viral reservoirs through PKC/MEK activation synergizing with vorinostat

Biochemical pharmacology, 2020-07, Vol.177, p.113937, Article 113937

2020

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