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Subgroup and Resistance Analyses of Raltegravir for Resistant HIV-1 Infection

The New England journal of medicine, 2008-07, Vol.359 (4), p.355-365

2008

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Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Antimicrobial agents and chemotherapy, 2016-12, Vol.60 (12), p.7086-7097

2016

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Structural basis of second-generation HIV integrase inhibitor action and viral resistance

Science (American Association for the Advancement of Science), 2020-02, Vol.367 (6479), p.806-810

2020

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Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase

Nature communications, 2020-12, Vol.11 (1), p.5922-10, Article 5922

2020

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Integrase strand transfer inhibitor (INSTI)-resistance mutations for the surveillance of transmitted HIV-1 drug resistance

Journal of antimicrobial chemotherapy, 2020-01, Vol.75 (1), p.170-182

2020

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New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

The Journal of biological chemistry, 2012-06, Vol.287 (25), p.21189-21203

2012

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Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs

Viruses, 2021-01, Vol.13 (2), p.205

2021

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The G118R plus R263K Combination of Integrase Mutations Associated with Dolutegravir-Based Treatment Failure Reduces HIV-1 Replicative Capacity and Integration

Antimicrobial agents and chemotherapy, 2023-05, Vol.67 (5), p.e0138622-e0138622

2023

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HIV RNA Screening Reduces Integrase Strand Transfer Inhibitor Resistance Risk in Persons Receiving Long-Acting Cabotegravir for HIV Prevention

The Journal of infectious diseases, 2022-12, Vol.226 (12), p.2170-2180

2022

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Transmitted Drug Resistance to Integrase-Based First-Line Human Immunodeficiency Virus Antiretroviral Regimens in Mediterranean Europe

Clinical infectious diseases, 2023-05, Vol.76 (9), p.1628-1635

2023

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Transmission of S230R integrase drug resistance mutation affecting second-generation integrase inhibitors in a French primary HIV-1 infected man

Journal of antimicrobial chemotherapy, 2023-07, Vol.78 (7), p.1802-1803

2023

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Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir

Retrovirology, 2018-08, Vol.15 (1), p.56-56, Article 56

2018

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Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4552-4559

2011

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Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians

Scientific reports, 2023-04, Vol.13 (1), p.6546-6546, Article 6546

2023

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Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells

PloS one, 2013-09, Vol.8 (9), p.e74163

2013

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Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors

The Journal of biological chemistry, 2012-05, Vol.287 (20), p.16801-16811

2012

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Inhibiting the HIV Integration Process: Past, Present, and the Future

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.539-566

Di Santo, Roberto

2014

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Preclinical Profile of BI 224436, a Novel HIV-1 Non-Catalytic-Site Integrase Inhibitor

Antimicrobial agents and chemotherapy, 2014-06, Vol.58 (6), p.3233-3244

2014

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Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation

Nature communications, 2019-02, Vol.10 (1), p.926-926, Article 926

2019

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Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors

Journal of medicinal chemistry, 2017-09, Vol.60 (17), p.7315-7332

2017

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Mutations Associated with Failure of Raltegravir Treatment Affect Integrase Sensitivity to the Inhibitor In Vitro

Antimicrobial Agents and Chemotherapy, 2008-04, Vol.52 (4), p.1351-1358

2008

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HIV-1 Protease, Reverse Transcriptase, and Integrase Variation

Journal of virology, 2016-07, Vol.90 (13), p.6058-6070

2016

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HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

Cell, 2016-08, Vol.166 (5), p.1257-1268.e12

2016

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Pre-treatment integrase inhibitor resistance is uncommon in antiretroviral therapy-naive individuals with HIV-1 subtype A1 and D infections in Uganda

AIDS (London), 2021-06, Vol.35 (7), p.1083-1089

2021

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Beware of resistance to 2nd-generation integrase inhibitors: A systematic meta-analysis of HIV-1 integrase inhibitors resistance and drug resistance mutations

International journal of antimicrobial agents, 2024-09, Vol.64 (3), p.107294, Article 107294

2024

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Subgroup and Resistance Analyses of Raltegravir for Resistant HIV-1 Infection

Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Structural basis of second-generation HIV integrase inhibitor action and viral resistance

Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase

Integrase strand transfer inhibitor (INSTI)-resistance mutations for the surveillance of transmitted HIV-1 drug resistance

New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs

The G118R plus R263K Combination of Integrase Mutations Associated with Dolutegravir-Based Treatment Failure Reduces HIV-1 Replicative Capacity and Integration

HIV RNA Screening Reduces Integrase Strand Transfer Inhibitor Resistance Risk in Persons Receiving Long-Acting Cabotegravir for HIV Prevention

Transmitted Drug Resistance to Integrase-Based First-Line Human Immunodeficiency Virus Antiretroviral Regimens in Mediterranean Europe

Transmission of S230R integrase drug resistance mutation affecting second-generation integrase inhibitors in a French primary HIV-1 infected man

Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians

Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells

Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors

Inhibiting the HIV Integration Process: Past, Present, and the Future

Preclinical Profile of BI 224436, a Novel HIV-1 Non-Catalytic-Site Integrase Inhibitor

Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation

Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors

Mutations Associated with Failure of Raltegravir Treatment Affect Integrase Sensitivity to the Inhibitor In Vitro

HIV-1 Protease, Reverse Transcriptase, and Integrase Variation

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

Pre-treatment integrase inhibitor resistance is uncommon in antiretroviral therapy-naive individuals with HIV-1 subtype A1 and D infections in Uganda

Beware of resistance to 2nd-generation integrase inhibitors: A systematic meta-analysis of HIV-1 integrase inhibitors resistance and drug resistance mutations

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