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Comparative proteomic analysis of Escherichia coli O157:H7 following ohmic and water bath heating by capillary-HPLC-MS/MS

International journal of food microbiology, 2018-11, Vol.285, p.42-49

2018

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Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate

Nature communications, 2022-02, Vol.13 (1), p.731-731, Article 731

2022

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G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms

The Journal of biological chemistry, 2017-06, Vol.292 (24), p.9932-9943

2017

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Structure, function and pharmacology of human itch GPCRs

Nature (London), 2021-12, Vol.600 (7887), p.170-175

2021

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Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

Nature (London), 2018-06, Vol.558 (7711), p.553-558

2018

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Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs

Nature structural & molecular biology, 2021-03, Vol.28 (3), p.258-267

2021

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On the selectivity of the Gαq inhibitor UBO-QIC: A comparison with the Gαi inhibitor pertussis toxin

Biochemical pharmacology, 2016-05, Vol.107, p.59-66

2016

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Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane

Nature (London), 2020-08, Vol.584 (7819), p.125-129

2020

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Label free-based proteomic analysis of Escherichia coli O157:H7 subjected to ohmic heating

Food research international, 2020-02, Vol.128, p.108815-108815, Article 108815

2020

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Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells

European journal of pharmacology, 2016-06, Vol.780, p.115-121

2016

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Caenorhabditis elegans provides an efficient drug screening platform for GNAO1-related disorders and highlights the potential role of caffeine in controlling dyskinesia

Human molecular genetics, 2022-03, Vol.31 (6), p.929-941

2022

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Stabilization of interdomain interactions in G protein α subunits as a determinant of Gαi subtype signaling specificity

The Journal of biological chemistry, 2024-05, Vol.300 (5), p.107211-107211, Article 107211

2024

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GPCR-G protein selectivity revealed by structural pharmacology

The FEBS journal, 2024-07, Vol.291 (13), p.2784-2791

2024

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Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel

Nature communications, 2019-05, Vol.10 (1), p.2008-2008, Article 2008

2019

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A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias

The Journal of biological chemistry, 2016-09, Vol.291 (36), p.18915-18931

2016

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A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state

Nature communications, 2024-08, Vol.15 (1), p.6643-18, Article 6643

2024

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Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (15), p.E3549-E3558

2018

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Activation of CXCL10/CXCR3 Signaling Attenuates Morphine Analgesia: Involvement of Gi Protein

Journal of molecular neuroscience, 2014-08, Vol.53 (4), p.571-579

2014

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Enhanced expression of Giα proteins contributes to the hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats via MAP kinase- and PI3 kinase-independent pathways

Canadian journal of physiology and pharmacology, 2016-01, Vol.94 (1), p.49-58

2016

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Structural and dynamic insights into the activation of the μ-opioid receptor by an allosteric modulator

Nature communications, 2024-05, Vol.15 (1), p.3544-3544, Article 3544

2024

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Growth factor-dependent phosphorylation of Gα i shapes canonical signaling by G protein-coupled receptors

Science signaling, 2024-06, Vol.17 (839), p.eade8041

2024

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The impact of RGS and other G-protein regulatory proteins on Gαi-mediated signaling in immunity

Biochemical pharmacology, 2016-08, Vol.114, p.40-52

Kehrl, John H.

2016

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Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A

Structure (London), 2019-07, Vol.27 (7), p.1137-1147.e5

2019

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Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

The Journal of experimental medicine, 2010-01, Vol.207 (1), p.17-27

2010

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Mu-Opioid Receptor Coupling to Gα Plays an Important Role in Opioid Antinociception

Neuropsychopharmacology (New York, N.Y.), 2011-09, Vol.36 (10), p.2041-2053

2011

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Comparative proteomic analysis of Escherichia coli O157:H7 following ohmic and water bath heating by capillary-HPLC-MS/MS

Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate

G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms

Structure, function and pharmacology of human itch GPCRs

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs

On the selectivity of the Gαq inhibitor UBO-QIC: A comparison with the Gαi inhibitor pertussis toxin

Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane

Label free-based proteomic analysis of Escherichia coli O157:H7 subjected to ohmic heating

Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells

Caenorhabditis elegans provides an efficient drug screening platform for GNAO1-related disorders and highlights the potential role of caffeine in controlling dyskinesia

Stabilization of interdomain interactions in G protein α subunits as a determinant of Gαi subtype signaling specificity

GPCR-G protein selectivity revealed by structural pharmacology

Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel

A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias

A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state

Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus

Activation of CXCL10/CXCR3 Signaling Attenuates Morphine Analgesia: Involvement of Gi Protein

Enhanced expression of Giα proteins contributes to the hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats via MAP kinase- and PI3 kinase-independent pathways

Structural and dynamic insights into the activation of the μ-opioid receptor by an allosteric modulator

Growth factor-dependent phosphorylation of Gα i shapes canonical signaling by G protein-coupled receptors

The impact of RGS and other G-protein regulatory proteins on Gαi-mediated signaling in immunity

Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

Mu-Opioid Receptor Coupling to Gα Plays an Important Role in Opioid Antinociception

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