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Epistasis and quantitative traits: using model organisms to study gene-gene interactions

Nature reviews. Genetics, 2014-01, Vol.15 (1), p.22

Mackay, Trudy F C

2014

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Inferring protein 3D structure from deep mutation scans

Nature genetics, 2019-07, Vol.51 (7), p.1170-1176

2019

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Detecting epistasis in human complex traits

Nature reviews. Genetics, 2014-11, Vol.15 (11), p.722

2014

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Synergistic epistasis among cancer drivers can rescue early tumors from the accumulation of deleterious passengers

PLoS computational biology, 2024-04, Vol.20 (4), p.e1012081-e1012081

2024

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Epistasis and evolution: recent advances and an outlook for prediction

BMC biology, 2023-05, Vol.21 (1), p.120-120

2023

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Detection and replication of epistasis influencing transcription in humans

Nature (London), 2014-04, Vol.508 (7495), p.249-253

2014

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Epistasis as the primary factor in molecular evolution

Nature (London), 2012-10, Vol.490 (7421), p.535-538

2012

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Identifying Epistasis in Cancer Genomes: A Delicate Affair

Cell, 2019-05, Vol.177 (6), p.1375-1383

2019

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Genetic incompatibilities are widespread within species

Nature (London), 2013-12, Vol.504 (7478), p.135-137

2013

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Modular epistasis and the compensatory evolution of gene deletion mutants

PLoS genetics, 2019-02, Vol.15 (2), p.e1007958-e1007958

2019

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Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits

PLoS genetics, 2017-07, Vol.13 (7), p.e1006869-e1006869

2017

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Initial mutations direct alternative pathways of protein evolution

PLoS genetics, 2011-03, Vol.7 (3), p.e1001321

2011

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Mapping mitonuclear epistasis using a novel recombinant yeast population

PLoS genetics, 2023-03, Vol.19 (3), p.e1010401-e1010401

2023

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Another explanation for apparent epistasis

Nature (London), 2014-10, Vol.514 (7520), p.E3-E5

2014

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The Context-Dependence of Mutations: A Linkage of Formalisms

PLoS computational biology, 2016-06, Vol.12 (6), p.e1004771-e1004771

2016

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High-order epistasis shapes evolutionary trajectories

PLoS computational biology, 2017-05, Vol.13 (5), p.e1005541-e1005541

2017

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α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

Nature genetics, 2009-03, Vol.41 (3), p.308-315

2009

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Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease

PLoS genetics, 2020-10, Vol.16 (10), p.e1009009

2020

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Significance of linkage disequilibrium and epistasis on genetic variances in noninbred and inbred populations

BMC genomics, 2022-04, Vol.23 (1), p.286-286, Article 286

2022

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PyToxo: a Python tool for calculating penetrance tables of high-order epistasis models

BMC bioinformatics, 2022-04, Vol.23 (1), p.117-117, Article 117

2022

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Phantom epistasis between unlinked loci

Nature (London), 2021-08, Vol.596 (7871), p.E1-E3

2021

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The rarA gene as part of an expanded RecFOR recombination pathway: Negative epistasis and synthetic lethality with ruvB, recG, and recQ

PLoS genetics, 2021-12, Vol.17 (12), p.e1009972-e1009972

2021

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Host heterogeneity and epistasis explain punctuated evolution of SARS-CoV-2

PLoS computational biology, 2023-02, Vol.19 (2), p.e1010896-e1010896

2023

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Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis

Blood, 2014-08, Vol.124 (8), p.1331-1334

2014

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Genomic prediction with epistasis models: on the marker-coding-dependent performance of the extended GBLUP and properties of the categorical epistasis model (CE)

BMC bioinformatics, 2017-01, Vol.18 (1), p.3-3, Article 3

2017

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Epistasis and quantitative traits: using model organisms to study gene-gene interactions

Inferring protein 3D structure from deep mutation scans

Detecting epistasis in human complex traits

Synergistic epistasis among cancer drivers can rescue early tumors from the accumulation of deleterious passengers

Epistasis and evolution: recent advances and an outlook for prediction

Detection and replication of epistasis influencing transcription in humans

Epistasis as the primary factor in molecular evolution

Identifying Epistasis in Cancer Genomes: A Delicate Affair

Genetic incompatibilities are widespread within species

Modular epistasis and the compensatory evolution of gene deletion mutants

Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits

Initial mutations direct alternative pathways of protein evolution

Mapping mitonuclear epistasis using a novel recombinant yeast population

Another explanation for apparent epistasis

The Context-Dependence of Mutations: A Linkage of Formalisms

High-order epistasis shapes evolutionary trajectories

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease

Significance of linkage disequilibrium and epistasis on genetic variances in noninbred and inbred populations

PyToxo: a Python tool for calculating penetrance tables of high-order epistasis models

Phantom epistasis between unlinked loci

The rarA gene as part of an expanded RecFOR recombination pathway: Negative epistasis and synthetic lethality with ruvB, recG, and recQ

Host heterogeneity and epistasis explain punctuated evolution of SARS-CoV-2

Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis

Genomic prediction with epistasis models: on the marker-coding-dependent performance of the extended GBLUP and properties of the categorical epistasis model (CE)

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