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Autophagy failure in Alzheimer's disease—locating the primary defect

Neurobiology of disease, 2011-07, Vol.43 (1), p.38-45

2011

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Neurodegenerative lysosomal disorders: A continuum from development to late age

Autophagy, 2008-07, Vol.4 (5), p.590-599

2008

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Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

Brain (London, England : 1878), 2011-01, Vol.134 (Pt 1), p.258-277

2011

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Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits

Brain (London, England : 1878), 2014-12, Vol.137 (Pt 12), p.3300-3318

2014

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Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration

Nature communications, 2022-09, Vol.13 (1), p.5308-5308, Article 5308

2022

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Transgenic expression of a ratiometric autophagy probe specifically in neurons enables the interrogation of brain autophagy in vivo

Autophagy, 2019-03, Vol.15 (3), p.543-557

2019

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Treating High COD Dyeing Wastewater via a Regenerative Sorption-Oxidation Process Using a Nano-Pored Activated Carbon

International journal of molecular sciences, 2022-04, Vol.23 (9), p.4752

2022

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Use of a Novel Biopellet to Treat Total Petroleum Hydrocarbon Contaminated Groundwater

Water (Basel), 2020-09, Vol.12 (9), p.2512

2020

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Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

Nature neuroscience, 2022-06, Vol.25 (6), p.688-701

2022

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Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer's Disease

The American journal of pathology, 2008-09, Vol.173 (3), p.665-681

2008

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Using Smoke Condensed Liquids from Pruned Fruit-Tree Branches for Aedes Mosquito Larva Control

Agriculture (Basel), 2022-06, Vol.12 (6), p.825

2022

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Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis

Autophagy, 2011-07, Vol.7 (7), p.788-789

2011

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Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression

The Journal of neuroscience, 2008-11, Vol.28 (47), p.12241-12254

2008

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Autophagy and neuronal cell death in neurological disorders

Cold Spring Harbor perspectives in biology, 2012-10, Vol.4 (10), p.a008839-a008839

2012

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Single-Walled Carbon Nanotubes Alleviate Autophagic/Lysosomal Defects in Primary Glia from a Mouse Model of Alzheimer’s Disease

Nano letters, 2014-09, Vol.14 (9), p.5110-5117

2014

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Elevation of GM2 ganglioside during ethanol-induced apoptotic neurodegeneration in the developing mouse brain

Journal of neurochemistry, 2012-05, Vol.121 (4), p.649-661

2012

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Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

Cell reports (Cambridge), 2021-04, Vol.35 (4), p.109034-109034, Article 109034

2021

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Chapter 6 Monitoring Autophagy in Alzheimer's Disease and Related Neurodegenerative Diseases

Methods in Enzymology, 2009, Vol.453, p.111-144

2009

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Autophagy is a novel pathway for neurofilament protein degradation in vivo

Autophagy, 2023-04, Vol.19 (4), p.1277-1292

2023

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Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice

Human molecular genetics, 2017-03, Vol.26 (5), p.843-859

2017

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Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins

The Journal of biological chemistry, 2002-08, Vol.277 (31), p.28135-28142

2002

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Development of a cell immobilization technique with polyvinyl alcohol for diesel remediation in seawater

International biodeterioration & biodegradation, 2016-09, Vol.113, p.397-407

2016

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing

Nature (London), 2000-09, Vol.407 (6800), p.48-54

2000

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Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments

Neurobiology of aging, 2011-11, Vol.32 (11), p.2016-2029

2011

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Characterization of the Binding of Amyloid‐β Peptide to Cell Culture‐Derived Native Apolipoprotein E2, E3, and E4 Isoforms and to Isoforms from Human Plasma

Journal of neurochemistry, 1997-02, Vol.68 (2), p.721-725

1997

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Autophagy failure in Alzheimer's disease—locating the primary defect

Neurodegenerative lysosomal disorders: A continuum from development to late age

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits

Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration

Transgenic expression of a ratiometric autophagy probe specifically in neurons enables the interrogation of brain autophagy in vivo

Treating High COD Dyeing Wastewater via a Regenerative Sorption-Oxidation Process Using a Nano-Pored Activated Carbon

Use of a Novel Biopellet to Treat Total Petroleum Hydrocarbon Contaminated Groundwater

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer's Disease

Using Smoke Condensed Liquids from Pruned Fruit-Tree Branches for Aedes Mosquito Larva Control

Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis

Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression

Autophagy and neuronal cell death in neurological disorders

Single-Walled Carbon Nanotubes Alleviate Autophagic/Lysosomal Defects in Primary Glia from a Mouse Model of Alzheimer’s Disease

Elevation of GM2 ganglioside during ethanol-induced apoptotic neurodegeneration in the developing mouse brain

Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

Chapter 6 Monitoring Autophagy in Alzheimer's Disease and Related Neurodegenerative Diseases

Autophagy is a novel pathway for neurofilament protein degradation in vivo

Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice

Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins

Development of a cell immobilization technique with polyvinyl alcohol for diesel remediation in seawater

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing

Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments

Characterization of the Binding of Amyloid‐β Peptide to Cell Culture‐Derived Native Apolipoprotein E2, E3, and E4 Isoforms and to Isoforms from Human Plasma

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