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Structural insights into selective small molecule activation of PKG1α

Communications biology, 2023-07, Vol.6 (1), p.798-798, Article 798

2023

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Inhibitors of Efflux Pumps in Pseudomonas aeruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin

Journal of medicinal chemistry, 1999-12, Vol.42 (24), p.4928-4931

1999

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Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (5), p.763-766

2002

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Predictions of Chromatography Methods by Chemical Structure Similarity to Accelerate High-Throughput Medicinal Chemistry

ACS medicinal chemistry letters, 2024-08, Vol.15 (8), p.1396-1401

2024

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Bicyclic pyrimidine compounds as potent IRAK4 inhibitors

Bioorganic & medicinal chemistry letters, 2022-10, Vol.73, p.128900-128900, Article 128900

2022

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Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1α

Journal of medicinal chemistry, 2022-08, Vol.65 (15), p.10318-10340

2022

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Optimization of Pyrimidine Compounds as Potent JAK1 Inhibitors and the Discovery of R507 as a Clinical Candidate

ACS medicinal chemistry letters, 2022-11, Vol.13 (11), p.1805-1811

2022

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Characterization of a small molecule IRAK4 kinase inhibitor for the treatment of autoimmune and inflammatory diseases

The Journal of immunology (1950), 2016-05, Vol.196 (1_Supplement), p.210-210.13

2016

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Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

Bioorganic & medicinal chemistry letters, 2003-08, Vol.13 (16), p.2755-2758

2003

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The relationship between physicochemical properties, In vitro activity and pharmacokinetic profiles of analogues of diamine-Containing efflux pump inhibitors

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4241-4244

2003

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N-Linked solid phase peptide synthesis

Tetrahedron letters, 1998-06, Vol.39 (24), p.4171-4174

1998

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Cytokinetics of a novel 1,2,3-triazene-containing heterocycle, 8-nitro-3-methyl-benzo-1,2,3,5-tetrazepin-4(3 H)-one (NIME), in the human epithelial ovarian cancer cell line OVCAR-3

Biochemical pharmacology, 1999-04, Vol.57 (7), p.753-762

1999

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The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors: Antibacterial agents: solutions for the evolving problems of resistance

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (23), p.4241-4244

2003

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Inhibitors of Efflux Pumps in Pseudomonas a eruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin

Journal of medicinal chemistry, 1999-12, Vol.42 (24), p.4928-4931

1999

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ChemInform Abstract: Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa

ChemInform, 2002-06, Vol.33 (25), p.no-no

2002

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Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis

Science (American Association for the Advancement of Science), 2021-09, Vol.373 (6561), p.eabj0486

2021

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Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis

Nature communications, 2023-04, Vol.14 (1), p.2194-2194, Article 2194

2023

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Mean State AMOC Affects AMOC Weakening through Subsurface Warming in the Labrador Sea

Journal of climate, 2023-06, Vol.36 (12), p.3895-3915

2023

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The Pantheon+ Analysis: Cosmological Constraints

The Astrophysical journal, 2022-10, Vol.938 (2), p.110

2022

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Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

Nature communications, 2019-01, Vol.10 (1), p.47-11, Article 47

2019

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The natural course of a localized BCG vaccine abscess

Vaccine, 2019-05, Vol.37 (20), p.2757-2757

2019

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The Limit of Detection Matters: The Case for Benchmarking Severe Acute Respiratory Syndrome Coronavirus 2 Testing

Clinical infectious diseases, 2021-02, Vol.73 (9), p.e3042-e3046

2021

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The Dominant Contribution of Southern Ocean Heat Uptake to Time‐Evolving Radiative Feedback in CESM

Geophysical research letters, 2021-05, Vol.48 (9), p.n/a

2021

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The Use of Proton and Carbon Ion Radiation Therapy for Sarcomas

Seminars in radiation oncology, 2024-04, Vol.34 (2), p.207-217

2024

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Structural insights into selective small molecule activation of PKG1α

Inhibitors of Efflux Pumps in Pseudomonas aeruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin

Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa

Predictions of Chromatography Methods by Chemical Structure Similarity to Accelerate High-Throughput Medicinal Chemistry

Bicyclic pyrimidine compounds as potent IRAK4 inhibitors

Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1α

Optimization of Pyrimidine Compounds as Potent JAK1 Inhibitors and the Discovery of R507 as a Clinical Candidate

Characterization of a small molecule IRAK4 kinase inhibitor for the treatment of autoimmune and inflammatory diseases

Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

The relationship between physicochemical properties, In vitro activity and pharmacokinetic profiles of analogues of diamine-Containing efflux pump inhibitors

N-Linked solid phase peptide synthesis

Cytokinetics of a novel 1,2,3-triazene-containing heterocycle, 8-nitro-3-methyl-benzo-1,2,3,5-tetrazepin-4(3 H)-one (NIME), in the human epithelial ovarian cancer cell line OVCAR-3

The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors: Antibacterial agents: solutions for the evolving problems of resistance

Inhibitors of Efflux Pumps in Pseudomonas a eruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin

ChemInform Abstract: Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa

Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis

Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis

Mean State AMOC Affects AMOC Weakening through Subsurface Warming in the Labrador Sea

The Pantheon+ Analysis: Cosmological Constraints

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

The natural course of a localized BCG vaccine abscess

The Limit of Detection Matters: The Case for Benchmarking Severe Acute Respiratory Syndrome Coronavirus 2 Testing

The Dominant Contribution of Southern Ocean Heat Uptake to Time‐Evolving Radiative Feedback in CESM

The Use of Proton and Carbon Ion Radiation Therapy for Sarcomas

Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses

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