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Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

Nature (London), 2003-05, Vol.423 (6939), p.555-560

2003

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Chronic pain treatment with pregabalin in end stage respiratory failure patients awaiting lung transplantation on ambulatory veno-venous extra corporeal membrane oxygenator support; a series of nine cases

Hippokratia, 2023-01, Vol.27 (1), p.22-24

2023

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Positioning accuracy for lung stereotactic body radiotherapy patients determined by on-treatment cone-beam CT imaging

British journal of radiology, 2012-06, Vol.85 (1014), p.819-823

2012

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The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol

Structure (London), 2007-05, Vol.15 (5), p.545-552

2007

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Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (18), p.7379-7384

2011

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SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.1034-1046

2006

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A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.417-422

2011

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A novel series of IKKβ inhibitors part II: Description of a potent and pharmacologically active series of analogs

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.423-426

2011

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Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (11), p.2842-2845

2006

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proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (24), p.9820-9825

2009

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Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11β-HSD1 inhibitors

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (6), p.1797-1801

2009

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Distinctive molecular inhibition mechanisms for selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1

Bioorganic & medicinal chemistry, 2008-10, Vol.16 (19), p.8922-8931

2008

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Thrombin generation and its inhibition: a review of the scientific basis and mechanism of action of anticoagulant therapies

British journal of anaesthesia : BJA, 2002-06, Vol.88 (6), p.848-863

2002

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Extracorporeal membrane oxygenator (ECMO) and ventricular assist device (VAD) activity of a tertiary cardiothoracic centre: survival rates and length of ITU stay

Critical care (London, England), 2015-01, Vol.19 (S1), p.P280-P280, Article P280

2015

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The high-resolution crystal structure of human LCAT

Journal of lipid research, 2015-09, Vol.56 (9), p.1711-1719

2015

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Crystal Structures of IRAK-4 Kinase in Complex with Inhibitors: A Serine/Threonine Kinase with Tyrosine as a Gatekeeper

Structure (London), 2006-12, Vol.14 (12), p.1835-1844

2006

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INT131: A Selective Modulator of PPARγ

Journal of molecular biology, 2009-03, Vol.386 (5), p.1301-1311

2009

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Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4

Bioorganic & medicinal chemistry letters, 2015-12, Vol.25 (23), p.5546-5550

2015

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Structure of tumour necrosis factor

Nature (London), 1989-03, Vol.338 (6212), p.225-228

1989

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BacMam production of active recombinant lecithin–cholesterol acyltransferase: Expression, purification and characterization

Protein expression and purification, 2016-09, Vol.125, p.1-6

2016

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Purine Nucleoside Phosphorylase Deficiency: A Mutation Update

Nucleosides, nucleotides & nucleic acids, 2011-12, Vol.30 (12), p.1243-1247

2011

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Quality of Life as a Treatment Outcome in Patients with Cystic Fibrosis

Pharmacotherapy, 1999-04, Vol.19 (4), p.393-398

1999

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Identification of a PPARδ agonist with partial agonistic activity on PPARγ

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3550-3554

2009

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MRI breast screening in high-risk women: cancer detection and survival analysis

Breast cancer research and treatment, 2014-06, Vol.145 (3), p.663-672

2014

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Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (5), p.1446-1450

2009

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