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TP53: an oncogene in disguise

Cell death and differentiation, 2015-08, Vol.22 (8), p.1239-1249

2015

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Pharmacological reactivation of mutant p53: from protein structure to the cancer patient

Oncogene, 2010-07, Vol.29 (30), p.4245-4252

Wiman, K G

2010

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Understanding cell cycle and cell death regulation provides novel weapons against human diseases

Journal of internal medicine, 2017-05, Vol.281 (5), p.483-495

2017

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Reactivation of mutant p53: molecular mechanisms and therapeutic potential

Oncogene, 2007-04, Vol.26 (15), p.2243-2254

2007

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APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells

Cell death & disease, 2015-06, Vol.6 (6), p.e1794-e1794

2015

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Correction to: Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s

Oncogene, 2023-02, Vol.42 (9), p.709-709

2023

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APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

Cell death & disease, 2013-10, Vol.4 (10), p.e881-e881

2013

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p53 talks to PARP: the increasing complexity of p53-induced cell death

Cell death and differentiation, 2013-11, Vol.20 (11), p.1438-1439

Wiman, K G

2013

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Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis

Oncogene, 2010-03, Vol.29 (9), p.1329-1338

2010

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Strategies for therapeutic targeting of the p53 pathway in cancer

Cell death and differentiation, 2006-06, Vol.13 (6), p.921-926

Wiman, K G

2006

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Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ

Oncogene, 2014-08, Vol.33 (35), p.4407-4417

2014

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Introduction to Nobel Conference: ‘The Cell Cycle and Cell Death in Disease’

Journal of internal medicine, 2017-05, Vol.281 (5), p.418-421

2017

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PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2

Oncogene, 2008-10, Vol.27 (51), p.6571-6580

2008

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Proteomic identification of p53-dependent protein phosphorylation

Oncogene, 2008-08, Vol.27 (35), p.4854-4859

2008

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Mutated and non‐mutated TP53 as targets in the treatment of leukaemia

British journal of haematology, 2008-05, Vol.141 (4), p.445-453

2008

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The p53 target Wig-1: a regulator of mRNA stability and stem cell fate?

Cell death and differentiation, 2011-09, Vol.18 (9), p.1434-1440

2011

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Small molecules that reactivate mutant p53

European journal of cancer (1990), 2003-09, Vol.39 (13), p.1828-1834

2003

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PRIMA-1 APR-246 targets mutant forms of p53 family members p63 and p73

Oncogene, 2010-12, Vol.29 (49), p.6442-6451

2010

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Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm

Cancer cell, 2007-10, Vol.12 (4), p.303-312

2007

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Effects of PRIMA‐1 on chronic lymphocytic leukaemia cells with and without hemizygous p53 deletion

British journal of haematology, 2004-11, Vol.127 (3), p.285-291

2004

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PRIMA‐1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion

British journal of haematology, 2006-01, Vol.132 (2), p.230-236

2006

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PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

Cancer cell, 2009-05, Vol.15 (5), p.376-388

2009

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Hypoxia induces p53-dependent transactivation and Fas CD95-dependent apoptosis

Cell death and differentiation, 2007-03, Vol.14 (3), p.411-421

2007

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Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s (vol 33, pg 4407, 2014)

ONCOGENE, 2023-01, Vol.42 (9), p.709

2023

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EBNA-5, an Epstein-Barr Virus-Encoded Nuclear Antigen, Binds to the Retinoblastoma and p53 Proteins

Proceedings of the National Academy of Sciences - PNAS, 1993-06, Vol.90 (12), p.5455-5459

1993

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TP53: an oncogene in disguise

Pharmacological reactivation of mutant p53: from protein structure to the cancer patient

Understanding cell cycle and cell death regulation provides novel weapons against human diseases

Reactivation of mutant p53: molecular mechanisms and therapeutic potential

APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells

Correction to: Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

p53 talks to PARP: the increasing complexity of p53-induced cell death

Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis

Strategies for therapeutic targeting of the p53 pathway in cancer

Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ

Introduction to Nobel Conference: ‘The Cell Cycle and Cell Death in Disease’

PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2

Proteomic identification of p53-dependent protein phosphorylation

Mutated and non‐mutated TP53 as targets in the treatment of leukaemia

The p53 target Wig-1: a regulator of mRNA stability and stem cell fate?

Small molecules that reactivate mutant p53

PRIMA-1 APR-246 targets mutant forms of p53 family members p63 and p73

Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm

Effects of PRIMA‐1 on chronic lymphocytic leukaemia cells with and without hemizygous p53 deletion

PRIMA‐1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion

PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

Hypoxia induces p53-dependent transactivation and Fas CD95-dependent apoptosis

Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s (vol 33, pg 4407, 2014)

EBNA-5, an Epstein-Barr Virus-Encoded Nuclear Antigen, Binds to the Retinoblastoma and p53 Proteins

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