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Precision Medicine in Cancer Therapy

1, 2019

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nab-Paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial

JNCI : Journal of the National Cancer Institute, 2015-02, Vol.107 (2), p.dju413-dju413

2015

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Tumor-Treating Fields: A Fourth Modality in Cancer Treatment

Clinical cancer research, 2018-01, Vol.24 (2), p.266-275

2018

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Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

Cancer cell, 2012-03, Vol.21 (3), p.418-429

2012

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Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells

PloS one, 2016-10, Vol.11 (10), p.e0165586-e0165586

2016

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Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer

PloS one, 2017-08, Vol.12 (8), p.e0183871-e0183871

2017

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Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression

Clinical cancer research, 2018-10, Vol.24 (19), p.4798-4807

2018

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Phase I pharmacokinetic and pharmacodynamic study of the pan-PI3K/mTORC vascular targeted pro-drug SF1126 in patients with advanced solid tumours and B-cell malignancies

European journal of cancer (1990), 2012-12, Vol.48 (18), p.3319-3327

2012

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Tumor-stroma interactions in pancreatic ductal adenocarcinoma

Molecular cancer therapeutics, 2007-04, Vol.6 (4), p.1186-1197

2007

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Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

Clinical cancer research, 2015-08, Vol.21 (15), p.3561-3568

2015

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NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors

European journal of cancer (1990), 2019-02, Vol.108, p.78-87

2019

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Phase I and Pharmacologic Study of OSI-774, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced Solid Malignancies

Journal of clinical oncology, 2001-07, Vol.19 (13), p.3267-3279

2001

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Perineural invasion and associated pain in pancreatic cancer

Nature reviews. Cancer, 2011-10, Vol.11 (10), p.695-707

2011

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Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells

PloS one, 2012-03, Vol.7 (3), p.e32783

2012

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Gemcitabine Plus nab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial

Journal of clinical oncology, 2011-12, Vol.29 (34), p.4548-4554

2011

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Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

The New England journal of medicine, 2015-07, Vol.373 (5), p.428-437

2015

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Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas

Clinical cancer research, 2012-08, Vol.18 (16), p.4249-4256

2012

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Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions

Genome medicine, 2020-09, Vol.12 (1), p.80-80, Article 80

2020

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Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

Journal of clinical oncology, 1997-06, Vol.15 (6), p.2403-2413

1997

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Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

The New England journal of medicine, 2013-10, Vol.369 (18), p.1691-1703

2013

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Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic Development

Journal of clinical oncology, 1999-11, Vol.17 (11), p.3631-3652

1999

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Phase I and Pharmacokinetics Trial of ABI-007, a Novel Nanoparticle Formulation of Paclitaxel in Patients With Advanced Nonhematologic Malignancies

Journal of clinical oncology, 2005-11, Vol.23 (31), p.7785-7793

2005

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Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers

Journal of clinical oncology, 2010-11, Vol.28 (33), p.4877-4883

2010

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Phase II trial of vatalanib in patients with advanced or metastatic pancreatic adenocarcinoma after first-line gemcitabine therapy (PCRT O4-001)

Cancer chemotherapy and pharmacology, 2014-08, Vol.74 (2), p.379-387

2014

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Precision Medicine in Cancer Therapy

nab-Paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial

Tumor-Treating Fields: A Fourth Modality in Cancer Treatment

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells

Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer

Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression

Phase I pharmacokinetic and pharmacodynamic study of the pan-PI3K/mTORC vascular targeted pro-drug SF1126 in patients with advanced solid tumours and B-cell malignancies

Tumor-stroma interactions in pancreatic ductal adenocarcinoma

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors

Phase I and Pharmacologic Study of OSI-774, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced Solid Malignancies

Perineural invasion and associated pain in pancreatic cancer

Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells

Gemcitabine Plus nab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas

Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic Development

Phase I and Pharmacokinetics Trial of ABI-007, a Novel Nanoparticle Formulation of Paclitaxel in Patients With Advanced Nonhematologic Malignancies

Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers

Phase II trial of vatalanib in patients with advanced or metastatic pancreatic adenocarcinoma after first-line gemcitabine therapy (PCRT O4-001)

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