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Homogeneous organic reductant based on 4,4′-tBu2-2,2′-bipyridine for cross-electrophile coupling

Tetrahedron letters, 2024-07, Vol.145, Article 155159

2024

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Homogeneous organic reductant based on 4,4′- Bu2-2,2′-bipyridine for cross-electrophile coupling

Tetrahedron letters, 2024-07, Vol.145, p.155159, Article 155159

2024

Volltextzugriff (PDF)

Developmental stage‐dependent effects of perceived predation risk on nestling tree swallows (Tachycineta bicolor)

Ecology (Durham), 2024-06, Vol.105 (6), p.e4307-n/a

2024

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Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

Cancer discovery, 2023-10, Vol.13 (10), p.2150

2023

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G protein–receptor kinases 5/6 are the key regulators of G protein–coupled receptor 35–arrestin interactions

The Journal of biological chemistry, 2023-10, Vol.299 (10), p.105218-105218, Article 105218

2023

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Social signal manipulation and environmental challenges have independent effects on physiology, internal microbiome, and reproductive performance in tree swallows (Tachycineta bicolor)

Journal of experimental zoology. Part A, Ecological and integrative physiology, 2023-10, Vol.339 (8), p.723-735

2023

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An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma

Journal of neuro-oncology, 2023-07, Vol.163 (3), p.635-645

2023

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Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels

Biomaterials, 2023-06, Vol.297, p.122121-122121, Article 122121

2023

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Extensive regional variation in the phenology of insects and their response to temperature across N orth A merica

Ecology (Durham), 2023-05, Vol.104 (5)

2023

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G protein–coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin

The Journal of biological chemistry, 2022-10, Vol.298 (10), p.102421-102421, Article 102421

2022

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Homogeneous Organic Electron Donors in Nickel-Catalyzed Reductive Transformations

Journal of organic chemistry, 2022-06, Vol.87 (12), p.7589-7609

2022

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Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1961-1978

2022

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Correction to “Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma”

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.886-887

2022

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Tunable and Practical Homogeneous Organic Reductants for Cross-Electrophile Coupling

Journal of the American Chemical Society, 2021-12, Vol.143 (49), p.21024-21036

2021

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Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells

Journal of molecular biology, 2021-11, Vol.433 (23), p.167294-167294, Article 167294

2021

Volltextzugriff (PDF)

Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.11129-11147

2021

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Pharmacological Targeting of Executioner Proteins: Controlling Life and Death

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.5276-5290

2021

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Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies

Clinical cancer research, 2021-04, Vol.27 (8), p.2340-2351

2021

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The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia

Oncoimmunology, 2021-01, Vol.10 (1), p.1943234-1943234

2021

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A Widely Applicable Dual Catalytic System for Cross-Electrophile Coupling Enabled by Mechanistic Studies

ACS catalysis, 2020-11, Vol.10 (21), p.12642-12656

2020

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Functional characterization of a PROTAC directed against BRAF mutant V600E

Nature chemical biology, 2020-11, Vol.16 (11), p.1170

2020

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Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.10061-10085

2020

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Full lifetime perspectives on the costs and benefits of lay-date variation in tree swallows

Ecology (Durham), 2020-09, Vol.101 (9), p.1-19

2020

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Homogeneous organic reductant based on 4,4′-tBu2-2,2′-bipyridine for cross-electrophile coupling

Homogeneous organic reductant based on 4,4′- Bu2-2,2′-bipyridine for cross-electrophile coupling

Developmental stage‐dependent effects of perceived predation risk on nestling tree swallows (Tachycineta bicolor)

Which Small Molecule? Selecting Chemical Probes for Use in Cancer Research and Target Validation

G protein–receptor kinases 5/6 are the key regulators of G protein–coupled receptor 35–arrestin interactions

Social signal manipulation and environmental challenges have independent effects on physiology, internal microbiome, and reproductive performance in tree swallows (Tachycineta bicolor)

An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma

Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels

Extensive regional variation in the phenology of insects and their response to temperature across N orth A merica

Comparing genomic variant identification protocols for Candida auris

Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor

G protein–coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin

Homogeneous Organic Electron Donors in Nickel-Catalyzed Reductive Transformations

Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases

Correction to “Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma”

Tunable and Practical Homogeneous Organic Reductants for Cross-Electrophile Coupling

Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells

Design, Synthesis, and Characterization of 4‑Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma

Pharmacological Targeting of Executioner Proteins: Controlling Life and Death

Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies

The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia

A Widely Applicable Dual Catalytic System for Cross-Electrophile Coupling Enabled by Mechanistic Studies

Functional characterization of a PROTAC directed against BRAF mutant V600E

Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma

Full lifetime perspectives on the costs and benefits of lay-date variation in tree swallows

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