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Molecular targeting of hypoxia in radiotherapy

Advanced drug delivery reviews, 2017-01, Vol.109, p.45-62

2017

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NanoStringNorm: an extensible R package for the pre-processing of NanoString mRNA and miRNA data

Bioinformatics (Oxford, England), 2012-06, Vol.28 (11), p.1546-1548

2012

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Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response

Breast cancer research : BCR, 2013-01, Vol.15 (1), p.R2-R2, Article R2

2013

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PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (12), p.4622-4627

2013

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

The Journal of clinical investigation, 2010-01, Vol.120 (1), p.127-141

2010

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The Roles of Reactive Oxygen Species and Autophagy in Mediating the Tolerance of Tumor Cells to Cycling Hypoxia

Seminars in radiation oncology, 2013-10, Vol.23 (4), p.252-261

2013

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“Translating” Tumor Hypoxia: Unfolded Protein Response (UPR)–Dependent and UPR-Independent Pathways

Molecular cancer research, 2006-07, Vol.4 (7), p.423-436

2006

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Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

Nature communications, 2014-10, Vol.5 (1), Article 5203

2014

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De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13117

2023

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Two phases of disulfide bond formation have differing requirements for oxygen

The Journal of cell biology, 2013-11, Vol.203 (4), p.615-627

2013

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Hypoxia and Predicting Radiation Response

Seminars in radiation oncology, 2015-10, Vol.25 (4), p.260-272

2015

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MATE2 Expression Is Associated with Cancer Cell Response to Metformin

PloS one, 2016-12, Vol.11 (12), p.e0165214

2016

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Hypoxia signalling through mTOR and the unfolded protein response in cancer

Nature reviews. Cancer, 2008-11, Vol.8 (11), p.851-864

2008

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

The EMBO journal, 2005-10, Vol.24 (19), p.3470-3481

2005

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Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs

Cancer research (Chicago, Ill.), 2015-10, Vol.75 (19), p.4211-4223

2015

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Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

Journal of the American College of Cardiology, 2008-04, Vol.51 (13), p.1258-1265

2008

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Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

Nature communications, 2019-03, Vol.10 (1), p.1436-14, Article 1436

2019

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Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors

BMC cancer, 2017-06, Vol.17 (1), p.418-418, Article 418

2017

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In Vivo Imaging Reveals Significant Tumor Vascular Dysfunction and Increased Tumor Hypoxia-Inducible Factor-1α Expression Induced by High Single-Dose Irradiation in a Pancreatic Tumor Model

International journal of radiation oncology, biology, physics, 2017-01, Vol.97 (1), p.184-194

2017

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Oncology Scan—How Radiation Effects on Cells in the Stromal Microenvironment Influence Tumor Development, Proliferation, and Recovery

International journal of radiation oncology, biology, physics, 2013-07, Vol.86 (4), p.593-595

2013

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Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress

Molecular and Cellular Biology, 2004-09, Vol.24 (17), p.7469-7482

2004

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Quantitative Visualization of Hypoxia and Proliferation Gradients Within Histological Tissue Sections

Frontiers in bioengineering and biotechnology, 2019-12, Vol.7, p.397-397

2019

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Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

The EMBO journal, 2006-03, Vol.25 (5), p.1114-1125

2006

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Development of TRACER: tissue roll for analysis of cellular environment and response

Biofabrication, 2016-10, Vol.8 (4), p.045008-045008

2016

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Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

British journal of cancer, 2016-05, Vol.114 (10), p.1071-1077

2016

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Molecular targeting of hypoxia in radiotherapy

NanoStringNorm: an extensible R package for the pre-processing of NanoString mRNA and miRNA data

Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

The Roles of Reactive Oxygen Species and Autophagy in Mediating the Tolerance of Tumor Cells to Cycling Hypoxia

“Translating” Tumor Hypoxia: Unfolded Protein Response (UPR)–Dependent and UPR-Independent Pathways

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models

Two phases of disulfide bond formation have differing requirements for oxygen

Hypoxia and Predicting Radiation Response

MATE2 Expression Is Associated with Cancer Cell Response to Metformin

Hypoxia signalling through mTOR and the unfolded protein response in cancer

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs

Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors

In Vivo Imaging Reveals Significant Tumor Vascular Dysfunction and Increased Tumor Hypoxia-Inducible Factor-1α Expression Induced by High Single-Dose Irradiation in a Pancreatic Tumor Model

Oncology Scan—How Radiation Effects on Cells in the Stromal Microenvironment Influence Tumor Development, Proliferation, and Recovery

Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress

Quantitative Visualization of Hypoxia and Proliferation Gradients Within Histological Tissue Sections

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

Development of TRACER: tissue roll for analysis of cellular environment and response

Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

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