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Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions

Angewandte Chemie (International ed.), 2011-01, Vol.50 (1), p.314-318

International ed. in English, 2011

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Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

eLife, 2017-02, Vol.6

2017

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Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages

Cell death & disease, 2021-05, Vol.12 (6), p.538-538, Article 538

2021

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Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

Nature communications, 2023-04, Vol.14 (1), p.2057-2057, Article 2057

2023

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Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport[S]

Journal of lipid research, 2010-12, Vol.51 (12), p.3443-3454

2010

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Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

Journal of molecular biology, 2010-01, Vol.395 (3), p.568-577

2010

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Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV

Structure (London), 2003-08, Vol.11 (8), p.947-959

2003

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Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

ChemMedChem, 2011-11, Vol.6 (11), p.2048-2054

2011

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The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment

Structure (London), 2006-04, Vol.14 (4), p.713-723

2006

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Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima

Structure (London), 2000-03, Vol.8 (3), p.265-276

2000

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The monotopic membrane protein human oxidosqualene cyclase is active as monomer

Biochemical and biophysical research communications, 2004-03, Vol.315 (2), p.247-254

2004

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Structural insight into function and regulation of carnitine palmitoyltransferase

Cellular and molecular life sciences : CMLS, 2009-08, Vol.66 (15), p.2489-2501

2009

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Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

Nature, 2004-11, Vol.432 (7013), p.118-122

2004

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MultiBacMam Bimolecular Fluorescence Complementation (BiFC) tool-kit identifies new small-molecule inhibitors of the CDK5-p25 protein-protein interaction (PPI)

Scientific reports, 2018-03, Vol.8 (1), p.5083-10, Article 5083

2018

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Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA

Malaria journal, 2016-03, Vol.15 (161), p.161-161, Article 161

2016

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Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP

Journal of structural biology, 2016-05, Vol.194 (2), p.191-198

2016

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Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

Journal of molecular biology, 2010-11, Vol.403 (4), p.562-577

2010

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Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin)

Acta crystallographica. Section D, Biological crystallography., 2011-02, Vol.67 (2), p.119-123

2011

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Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design

Journal of molecular biology, 2010-03, Vol.397 (2), p.508-519

2010

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Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds

Journal of medicinal chemistry, 2013-12, Vol.56 (23), p.9789-9801

2013

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Structural Evidence for Evolution of the β/α Barrel Scaffold by Gene Duplication and Fusion

Science (American Association for the Advancement of Science), 2000-09, Vol.289 (5484), p.1546-1550

2000

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Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

The Journal of biological chemistry, 2016-07, Vol.291 (31), p.16292-16306

2016

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Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones

Acta crystallographica. Section D, Biological crystallography., 2013-06, Vol.69 (6), p.1124-1137

2013

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Light it up: Highly efficient multigene delivery in mammalian cells

BioEssays, 2011-12, Vol.33 (12), p.946-955

2011

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Generation of an antibody toolbox to characterize hERG

Biochemical and biophysical research communications, 2013-02, Vol.431 (1), p.70-75

2013

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Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions

Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport[S]

Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV

Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment

Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima

The monotopic membrane protein human oxidosqualene cyclase is active as monomer

Structural insight into function and regulation of carnitine palmitoyltransferase

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

MultiBacMam Bimolecular Fluorescence Complementation (BiFC) tool-kit identifies new small-molecule inhibitors of the CDK5-p25 protein-protein interaction (PPI)

Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA

Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP

Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin)

Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design

Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds

Structural Evidence for Evolution of the β/α Barrel Scaffold by Gene Duplication and Fusion

Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones

Light it up: Highly efficient multigene delivery in mammalian cells

Generation of an antibody toolbox to characterize hERG

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