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Homing Endonucleases: From Microbial Genetic Invaders to Reagents for Targeted DNA Modification

Structure (London), 2011-01, Vol.19 (1), p.7-15

Stoddard, Barry L.

2011

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Biocontainment of genetically modified organisms by synthetic protein design

Nature (London), 2015-02, Vol.518 (7537), p.55-60

2015

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The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

Science (American Association for the Advancement of Science), 2012-02, Vol.335 (6069), p.716-719

2012

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A synthetic sex ratio distortion system for the control of the human malaria mosquito

Nature communications, 2014-06, Vol.5 (1), p.3977, Article 3977

2014

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Homing endonucleases from mobile group I introns: discovery to genome engineering

Mobile DNA, 2014-03, Vol.5 (1), p.7-7

Stoddard, Barry L

2014

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Computational protein design enables a novel one-carbon assimilation pathway

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (12), p.3704-3709

2015

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Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

Science (American Association for the Advancement of Science), 2010-07, Vol.329 (5989), p.309-313

2010

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TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins

Trends in cell biology, 2013-08, Vol.23 (8), p.390-398

2013

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Increased Diels-Alderase activity through backbone remodeling guided by Foldit players

Nature biotechnology, 2012-02, Vol.30 (2), p.190-192

2012

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Control of repeat-protein curvature by computational protein design

Nature structural & molecular biology, 2015-02, Vol.22 (2), p.167-174

2015

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Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system

Nucleic acids research, 2022-05, Vol.50 (9), p.5171-5190

2022

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A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

Cell, 2014-06, Vol.157 (7), p.1644-1656

2014

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De Novo Computational Design of Retro-Aldol Enzymes

Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5868), p.1387-1391

2008

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Redesign of extensive protein—DNA interfaces of meganucleases using iterative cycles of in vitro compartmentalization

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4061-4066

2014

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Engineering altered protein–DNA recognition specificity

Nucleic acids research, 2018-06, Vol.46 (10), p.4845-4871

2018

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TAL effectors: function, structure, engineering and applications

Current opinion in structural biology, 2013-02, Vol.23 (1), p.93-99

2013

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De novo design of knotted tandem repeat proteins

Nature communications, 2023-10, Vol.14 (1), p.6746-6746, Article 6746

2023

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The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1

PloS one, 2023-11, Vol.18 (11), p.e0291267-e0291267

2023

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Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis

Nature chemical biology, 2012-02, Vol.8 (3), p.294-300

2012

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The effect of increasing numbers of repeats on TAL effector DNA binding specificity

Nucleic acids research, 2017-06, Vol.45 (11), p.6960-6970

2017

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Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition

Structure (London), 2020-07, Vol.28 (7), p.760-775.e8

2020

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Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

eLife, 2019-09, Vol.8

2019

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Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor

Nucleic acids research, 2023-05, Vol.51 (8), p.3513-3528

2023

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Computational Thermostabilization of an Enzyme

Science (American Association for the Advancement of Science), 2005-05, Vol.308 (5723), p.857-860

2005

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Incorporation of sensing modalities into de novo designed fluorescence-activating proteins

Nature communications, 2021-02, Vol.12 (1), p.856-856, Article 856

2021

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Homing Endonucleases: From Microbial Genetic Invaders to Reagents for Targeted DNA Modification

Biocontainment of genetically modified organisms by synthetic protein design

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

A synthetic sex ratio distortion system for the control of the human malaria mosquito

Homing endonucleases from mobile group I introns: discovery to genome engineering

Computational protein design enables a novel one-carbon assimilation pathway

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins

Increased Diels-Alderase activity through backbone remodeling guided by Foldit players

Control of repeat-protein curvature by computational protein design

Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

De Novo Computational Design of Retro-Aldol Enzymes

Redesign of extensive protein—DNA interfaces of meganucleases using iterative cycles of in vitro compartmentalization

Engineering altered protein–DNA recognition specificity

TAL effectors: function, structure, engineering and applications

De novo design of knotted tandem repeat proteins

The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis

The effect of increasing numbers of repeats on TAL effector DNA binding specificity

Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition

Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor

Computational Thermostabilization of an Enzyme

Incorporation of sensing modalities into de novo designed fluorescence-activating proteins

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