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Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (31), p.12669-12674

2011

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Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions

Angewandte Chemie (International ed.), 2011-01, Vol.50 (1), p.314-318

International ed. in English, 2011

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Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

Journal of molecular biology, 2010-01, Vol.395 (3), p.568-577

2010

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Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV

Structure (London), 2003-08, Vol.11 (8), p.947-959

2003

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Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

ChemMedChem, 2011-11, Vol.6 (11), p.2048-2054

2011

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Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor

Frontiers in pharmacology, 2022-01, Vol.12, p.699535-699535

2022

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A Fluorine Scan of Thrombin Inhibitors to Map the Fluorophilicity/Fluorophobicity of an Enzyme Active Site: Evidence for CF⋅⋅⋅CO Interactions

Angewandte Chemie (International ed.), 2003-06, Vol.42 (22), p.2507-2511

2003

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The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment

Structure (London), 2006-04, Vol.14 (4), p.713-723

2006

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The monotopic membrane protein human oxidosqualene cyclase is active as monomer

Biochemical and biophysical research communications, 2004-03, Vol.315 (2), p.247-254

2004

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Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

Nature, 2004-11, Vol.432 (7013), p.118-122

2004

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Domain swap in the C‐terminal ubiquitin‐like domain of human doublecortin

Acta crystallographica. Section D, Biological crystallography., 2018-05, Vol.74 (5), p.450-462

2018

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The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions

Acta crystallographica. Section D, Biological crystallography., 2003-02, Vol.59 (2), p.396-399

2003

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A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro

Molecular endocrinology (Baltimore, Md.), 2006-04, Vol.20 (4), p.809-830

2006

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Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

Journal of molecular biology, 2010-11, Vol.403 (4), p.562-577

2010

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Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin)

Acta crystallographica. Section D, Biological crystallography., 2011-02, Vol.67 (2), p.119-123

2011

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Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design

Journal of molecular biology, 2010-03, Vol.397 (2), p.508-519

2010

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Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds

Journal of medicinal chemistry, 2013-12, Vol.56 (23), p.9789-9801

2013

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Structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa

Acta crystallographica. Section D, Biological crystallography., 2013-01, Vol.69 (1), p.24-31

2013

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Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

The Journal of biological chemistry, 2016-07, Vol.291 (31), p.16292-16306

2016

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Tyramine fragment binding to BACE-1

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1304-1307

2008

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Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones

Acta crystallographica. Section D, Biological crystallography., 2013-06, Vol.69 (6), p.1124-1137

2013

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Quantification of Cation-π Interactions in Protein-Ligand Complexes: Crystal-Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion Ligand

Angewandte Chemie (International ed.), 2005-07, Vol.44 (28), p.4400-4404

2005

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Catechol-O-methyltransferase in complex with substituted 3′-deoxyribose bisubstrate inhibitors

Acta crystallographica. Section D, Biological crystallography., 2012-03, Vol.68 (3), p.253-260

2012

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Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions

Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines

Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV

Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments

Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor

A Fluorine Scan of Thrombin Inhibitors to Map the Fluorophilicity/Fluorophobicity of an Enzyme Active Site: Evidence for CF⋅⋅⋅CO Interactions

The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment

The monotopic membrane protein human oxidosqualene cyclase is active as monomer

DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

Domain swap in the C‐terminal ubiquitin‐like domain of human doublecortin

The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions

A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro

Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin)

Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design

Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds

Structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa

Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

Tyramine fragment binding to BACE-1

Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones

Quantification of Cation-π Interactions in Protein-Ligand Complexes: Crystal-Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion Ligand

Catechol-O-methyltransferase in complex with substituted 3′-deoxyribose bisubstrate inhibitors

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