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The PPARs: From Orphan Receptors to Drug Discovery

Journal of medicinal chemistry, 2000-02, Vol.43 (4), p.527-550

2000

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Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

Molecular cell, 1999-03, Vol.3 (3), p.397-403

1999

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A Selective Peroxisome Proliferator-Activated Receptor δ Agonist Promotes Reverse Cholesterol Transport

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (9), p.5306-5311

2001

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Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (9), p.1517-1521

2003

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Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase I

Journal of medicinal chemistry, 1995-02, Vol.38 (3), p.395-401

1995

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Sequence-Specific Targeting of Duplex DNA Using a Camptothecin-Triple Helix Forming Oligonucleotide Conjugate and Topoisomerase I

Journal of the American Chemical Society, 1997-07, Vol.119 (29), p.6939-6940

1997

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Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2345-2350

2011

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A short, enantioselective synthesis of the carbocyclic nucleoside carbovir

Journal of organic chemistry, 1991-08, Vol.56 (16), p.4990-4993

1991

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Reactions of a Cyclic Rhodium Carbenoid with Aromatic Compounds and Vinyl Ethers

Journal of organic chemistry, 1995-04, Vol.60 (7), p.2112-2124

1995

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Identification of a series of PPARγ/δ dual agonists via solid-Phase parallel synthesis

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (22), p.2959-2962

2001

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Identification of a series of oxadiazole-substituted α-isopropoxy phenylpropanoic acids with activity on PPARα, PPARγ, and PPARδ

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (17), p.2385-2388

2001

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A novel deprotection/functionalisation sequence using 2,4-dinitrobenzenesulfonamide: Part 2

Tetrahedron letters, 1998-03, Vol.39 (13), p.1673-1676

1998

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Synthesis and biological activity of l-tyrosine-based PPARγ agonists with reduced molecular weight

Bioorganic & medicinal chemistry letters, 2001-12, Vol.11 (24), p.3111-3113

2001

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A novel deprotection/functionalisation sequence using 2,4-dinitrobenzenesulfonamide: Part 1

Tetrahedron letters, 1998-03, Vol.39 (13), p.1669-1672

1998

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A Novel Method for the Generation of Nitrile Oxides on Solid Phase: Application to the Synthesis of Substituted Benzopyranoisoxazoles

Organic letters, 2002-02, Vol.4 (3), p.323-326

2002

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In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues

Cancer research (Chicago, Ill.), 1995-02, Vol.55 (3), p.603-609

1995

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Peptide Ligands of pp60c-src SH2 Domains: A Thermodynamic and Structural Study

Biochemistry (Easton), 1997-05, Vol.36 (21), p.6283-6293

1997

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Rigid Analogs of Camptothecin as DNA Topoisomerase I Inhibitors

Journal of medicinal chemistry, 1995-03, Vol.38 (6), p.906-911

1995

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Water Soluble Inhibitors of Topoisomerase I: Quaternary Salt Derivatives of Camptothecin

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.713-719

1996

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Synthesis of polyquinanes. 3. The total synthesis of (.+-.)-hirsutene: the intramolecular Diels-Alder approach

Journal of organic chemistry, 1990-04, Vol.55 (9), p.2725-2736

1990

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Reactions of Fervenulone. An Unprecedented Ring Contraction of a 7-Azapteridine Ring System

Journal of organic chemistry, 1995-10, Vol.60 (21), p.7063-7065

1995

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Cyclodextrin catalysis in the intramolecular Diels-Alder reaction with the furan diene

Journal of the American Chemical Society, 1982-10, Vol.104 (21), p.5853-5854

1982

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Phenoxyacetic acids as PPAR[delta] partial agonists: Synthesis, optimization, and in vivo efficacy

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2345-2350

2011

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Potent Dipeptide Inhibitors of the pp60 c - src SH2 Domain

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1894-1908

1998

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Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study

Biochemistry (Easton), 1997-05, Vol.36 (21), p.6283-6293

1997

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The PPARs: From Orphan Receptors to Drug Discovery

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

A Selective Peroxisome Proliferator-Activated Receptor δ Agonist Promotes Reverse Cholesterol Transport

Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity

Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase I

Sequence-Specific Targeting of Duplex DNA Using a Camptothecin-Triple Helix Forming Oligonucleotide Conjugate and Topoisomerase I

Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy

A short, enantioselective synthesis of the carbocyclic nucleoside carbovir

Reactions of a Cyclic Rhodium Carbenoid with Aromatic Compounds and Vinyl Ethers

Identification of a series of PPARγ/δ dual agonists via solid-Phase parallel synthesis

Identification of a series of oxadiazole-substituted α-isopropoxy phenylpropanoic acids with activity on PPARα, PPARγ, and PPARδ

A novel deprotection/functionalisation sequence using 2,4-dinitrobenzenesulfonamide: Part 2

Synthesis and biological activity of l-tyrosine-based PPARγ agonists with reduced molecular weight

A novel deprotection/functionalisation sequence using 2,4-dinitrobenzenesulfonamide: Part 1

A Novel Method for the Generation of Nitrile Oxides on Solid Phase: Application to the Synthesis of Substituted Benzopyranoisoxazoles

In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues

Peptide Ligands of pp60c-src SH2 Domains: A Thermodynamic and Structural Study

Rigid Analogs of Camptothecin as DNA Topoisomerase I Inhibitors

Water Soluble Inhibitors of Topoisomerase I: Quaternary Salt Derivatives of Camptothecin

Synthesis of polyquinanes. 3. The total synthesis of (.+-.)-hirsutene: the intramolecular Diels-Alder approach

Reactions of Fervenulone. An Unprecedented Ring Contraction of a 7-Azapteridine Ring System

Cyclodextrin catalysis in the intramolecular Diels-Alder reaction with the furan diene

Phenoxyacetic acids as PPAR[delta] partial agonists: Synthesis, optimization, and in vivo efficacy

Potent Dipeptide Inhibitors of the pp60 c - src SH2 Domain

Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study

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