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Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

Microbiology spectrum, 2022-04, Vol.10 (2), p.e0216721

2022

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The Titration Paradox Turns Pharmacology Upside Down

Clinical pharmacology and therapeutics, 2021-08, Vol.110 (2), p.292-293

2021

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Individualized treatment strategies for hyperuricemia informed by a semi‐mechanistic exposure‐response model of uric acid dynamics

Physiological reports, 2018-03, Vol.6 (5), p.e13614-n/a

2018

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Integrating dose estimation into a decision‐making framework for model‐based drug development

Pharmaceutical statistics : the journal of the pharmaceutical industry, 2018-03, Vol.17 (2), p.155-168

2018

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Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model

Journal for immunotherapy of cancer, 2018-02, Vol.6 (1), p.17-15, Article 17

2018

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Drug-disease modeling in the pharmaceutical industry - where mechanistic systems pharmacology and statistical pharmacometrics meet

European journal of pharmaceutical sciences, 2017-11, Vol.109, p.S39-S46

2017

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Dynamic predictions of patient survival using longitudinal tumor size in non-small cell lung cancer: Approach towards personalized medicine

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.e20606-e20606

2017

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Survival prediction using time-evolving tumor load: An approach to rationally design treatment sequencing, staging, and dosing strategies for oncology combinations

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.e20040-e20040

2017

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Exposure‐Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients With Prior Myocardial Infarction

Journal of clinical pharmacology, 2017-05, Vol.57 (5), p.573-583

2017

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Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology Modeling Approach

The Journal of pharmacology and experimental therapeutics, 2017-02, Vol.360 (2), p.356-367

2017

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Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation

Drug metabolism and disposition, 2014-09, Vol.42 (9), p.1367-1378

2014

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Comment on the report "limitations of model-based dose selection for indacaterol in patients with chronic obstructive pulmonary disease"

International journal of clinical pharmacology and therapeutics, 2012-09, Vol.50 (9), p.631-637

2012

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Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches

Respiratory research, 2011-04, Vol.12 (53), p.54-54, Article 54

2011

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Innovative approaches to clinical development and trial design

Annali dell'Istituto superiore di sanità, 2011, Vol.47 (1), p.8-13

2011

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Innovative approaches to clinical development and trial design: New challenges in translational medicine: transforming the advancement of science into cures

Annali dell'Istituto superiore di sanità, 2011, Vol.47 (1), p.8-13

2011

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Understanding pharmacokinetics using realistic computational models of fluid dynamics: biosimulation of drug distribution within the CSF space for intrathecal drugs

Journal of pharmacokinetics and pharmacodynamics, 2010-12, Vol.37 (6), p.629-644

2010

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Fostering Culture and Optimizing Organizational Structure for Implementing Model-Based Drug Development

Journal of clinical pharmacology, 2010-09, Vol.50 (S9), p.146S-150S

2010

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The future of drug development: advancing clinical trial design

Nature reviews. Drug discovery, 2009-12, Vol.8 (12), p.949-957

2009

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Communicating With the FDA: The "Third Rail" of a New Model for Drug Development

Journal of clinical pharmacology, 2008-02, Vol.48 (2), p.144-145

2008

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Current issues relating to drug safety especially with regard to the use of biomarkers: A meeting report and progress update

European journal of pharmaceutical sciences, 2007-02, Vol.30 (2), p.107-112

2007

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Enriched analgesic efficacy studies: An assessment by clinical trial simulation

Contemporary clinical trials, 2006-04, Vol.27 (2), p.165-173

2006

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Gerry???s Real World Guide to Pharmacokinetics and Other Things

Anesthesia and analgesia, 2006-03, Vol.102 (3), p.977

Stanski, Donald R.

2006

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Inadequate anaesthesia in lethal injection for execution/Authors' reply

The Lancet (British edition), 2005-09, Vol.366 (9491), p.1073

2005

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Inadequate anaesthesia in lethal injection for execution

The Lancet (British edition), 2005-09, Vol.366 (9491), p.1073-1073

Groner, Jonathan I

2005

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Inadequate anaesthesia in lethal injection for execution

The Lancet (British edition), 2005-09, Vol.366 (9491), p.1073-1074

2005

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Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

The Titration Paradox Turns Pharmacology Upside Down

Individualized treatment strategies for hyperuricemia informed by a semi‐mechanistic exposure‐response model of uric acid dynamics

Integrating dose estimation into a decision‐making framework for model‐based drug development

Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model

Drug-disease modeling in the pharmaceutical industry - where mechanistic systems pharmacology and statistical pharmacometrics meet

Dynamic predictions of patient survival using longitudinal tumor size in non-small cell lung cancer: Approach towards personalized medicine

Survival prediction using time-evolving tumor load: An approach to rationally design treatment sequencing, staging, and dosing strategies for oncology combinations

Exposure‐Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients With Prior Myocardial Infarction

Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology Modeling Approach

Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation

Comment on the report "limitations of model-based dose selection for indacaterol in patients with chronic obstructive pulmonary disease"

Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches

Innovative approaches to clinical development and trial design

Innovative approaches to clinical development and trial design: New challenges in translational medicine: transforming the advancement of science into cures

Understanding pharmacokinetics using realistic computational models of fluid dynamics: biosimulation of drug distribution within the CSF space for intrathecal drugs

Fostering Culture and Optimizing Organizational Structure for Implementing Model-Based Drug Development

The future of drug development: advancing clinical trial design

Communicating With the FDA: The "Third Rail" of a New Model for Drug Development

Current issues relating to drug safety especially with regard to the use of biomarkers: A meeting report and progress update

Enriched analgesic efficacy studies: An assessment by clinical trial simulation

Gerry???s Real World Guide to Pharmacokinetics and Other Things

Inadequate anaesthesia in lethal injection for execution/Authors' reply

Inadequate anaesthesia in lethal injection for execution

Inadequate anaesthesia in lethal injection for execution

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