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Carboxylic Acid (Bio)Isosteres in Drug Design

ChemMedChem, 2013-03, Vol.8 (3), p.385-395

2013

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The Daphniphyllum Alkaloids: Total Synthesis of (−)-Calyciphylline N

Journal of the American Chemical Society, 2015-03, Vol.137 (10), p.3510-3519

2015

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25th Anniversary of Organic Letters

Organic letters, 2023-07, Vol.25 (27), p.4955-4955

Smith, Amos B.

2023

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Evolution of Anion Relay Chemistry: Construction of Architecturally Complex Natural Products

Accounts of chemical research, 2020-04, Vol.53 (4), p.988-1000

2020

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Total Synthesis of the Reported Structure of Neaumycin B

Journal of the American Chemical Society, 2023-08, Vol.145 (33), p.18240-18246

2023

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Oxidative [1,2]-Brook Rearrangements Exploiting Single-Electron Transfer: Photoredox-Catalyzed Alkylations and Arylations

Journal of the American Chemical Society, 2017-07, Vol.139 (28), p.9487-9490

2017

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Peptide/Protein Stapling and Unstapling: Introduction of s‑Tetrazine, Photochemical Release, and Regeneration of the Peptide/Protein

Journal of the American Chemical Society, 2015-04, Vol.137 (12), p.4034-4037

2015

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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Science (American Association for the Advancement of Science), 2014-11, Vol.346 (6210), p.759-763

2014

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Structure Property Relationships of Carboxylic Acid Isosteres

Journal of medicinal chemistry, 2016-04, Vol.59 (7), p.3183-3203

2016

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Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity

PLoS pathogens, 2011-06, Vol.7 (6), p.e1002101-e1002101

2011

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Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation

Nature communications, 2021-03, Vol.12 (1), p.1950-1950, Article 1950

2021

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Total Synthesis of (−)-Mandelalide A Exploiting Anion Relay Chemistry (ARC): Identification of a Type II ARC/CuCN Cross-Coupling Protocol

Journal of the American Chemical Society, 2016-03, Vol.138 (11), p.3675-3678

2016

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Total Synthesis of (−)-Calyciphylline N

Journal of the American Chemical Society, 2014-01, Vol.136 (3), p.870-873

2014

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CD4 mimetics sensitize HIV-1-infected cells to ADCC

Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (20), p.E2687-E2694

2015

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Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs

Neurobiology of disease, 2017-09, Vol.105, p.328-335

2017

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Through-Bond/Through-Space Anion Relay Chemistry Exploiting Vinylepoxides as Bifunctional Linchpins

Angewandte Chemie (International ed.), 2014-01, Vol.53 (5), p.1279-1282

International ed. in English, 2014

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C≡N stretching vibration of 5-cyanotryptophan as an infrared probe of protein local environment: what determines its frequency?

Physical chemistry chemical physics : PCCP, 2016-03, Vol.18 (10), p.7027-7034

2016

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The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

Nature communications, 2017-10, Vol.8 (1), p.1049-12, Article 1049

2017

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Conformations of Human Immunodeficiency Virus Envelope Glycoproteins in Detergents and Styrene-Maleic Acid Lipid Particles

Journal of virology, 2023-06, Vol.97 (6), p.e0032723-e0032723

2023

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Total synthesis of architecturally complex indole terpenoids: strategic and tactical evolution

Journal of antibiotics, 2018-02, Vol.71 (2), p.185-204

2018

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Microtubule Stabilizing Agents as Potential Treatment for Alzheimer’s Disease and Related Neurodegenerative Tauopathies

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.8979-8996

2012

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Anion Relay Chemistry: Development of an Effective Diastereoselective [3+2] Annulation Tactic Exploiting an Aldol/Brook Rearrangement/Cyclization Cascade

Angewandte Chemie (International ed.), 2017-11, Vol.56 (45), p.14102-14106

International ed. in English, 2017

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Total Synthesis of (−)-Nodulisporic Acids D, C, and B: Evolution of a Unified Synthetic Strategy

Journal of the American Chemical Society, 2018-08, Vol.140 (30), p.9502-9511

2018

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Access to the Akuammiline Family of Alkaloids: Total Synthesis of (+)-Scholarisine A

Journal of the American Chemical Society, 2013-01, Vol.135 (1), p.519-528

2013

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Carboxylic Acid (Bio)Isosteres in Drug Design

The Daphniphyllum Alkaloids: Total Synthesis of (−)-Calyciphylline N

25th Anniversary of Organic Letters

Evolution of Anion Relay Chemistry: Construction of Architecturally Complex Natural Products

Total Synthesis of the Reported Structure of Neaumycin B

Oxidative [1,2]-Brook Rearrangements Exploiting Single-Electron Transfer: Photoredox-Catalyzed Alkylations and Arylations

Peptide/Protein Stapling and Unstapling: Introduction of s‑Tetrazine, Photochemical Release, and Regeneration of the Peptide/Protein

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET

Structure Property Relationships of Carboxylic Acid Isosteres

Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity

Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation

Total Synthesis of (−)-Mandelalide A Exploiting Anion Relay Chemistry (ARC): Identification of a Type II ARC/CuCN Cross-Coupling Protocol

Total Synthesis of (−)-Calyciphylline N

CD4 mimetics sensitize HIV-1-infected cells to ADCC

Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs

Through-Bond/Through-Space Anion Relay Chemistry Exploiting Vinylepoxides as Bifunctional Linchpins

C≡N stretching vibration of 5-cyanotryptophan as an infrared probe of protein local environment: what determines its frequency?

The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

Conformations of Human Immunodeficiency Virus Envelope Glycoproteins in Detergents and Styrene-Maleic Acid Lipid Particles

Total synthesis of architecturally complex indole terpenoids: strategic and tactical evolution

Microtubule Stabilizing Agents as Potential Treatment for Alzheimer’s Disease and Related Neurodegenerative Tauopathies

Anion Relay Chemistry: Development of an Effective Diastereoselective [3+2] Annulation Tactic Exploiting an Aldol/Brook Rearrangement/Cyclization Cascade

Total Synthesis of (−)-Nodulisporic Acids D, C, and B: Evolution of a Unified Synthetic Strategy

Access to the Akuammiline Family of Alkaloids: Total Synthesis of (+)-Scholarisine A

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