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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Science (American Association for the Advancement of Science), 2014-11, Vol.346 (6210), p.759-763

2014

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HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

eLife, 2018-03, Vol.7

2018

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Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

The Journal of experimental medicine, 2008-08, Vol.205 (8), p.1797-1805

2008

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Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10

PloS one, 2020-01, Vol.15 (1), p.e0227533-e0227533

2020

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Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions

Nature communications, 2018-10, Vol.9 (1), p.4489-14, Article 4489

2018

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HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV

Journal of translational medicine, 2011-01, Vol.9 Suppl 1 (S1), p.S2-S2, Article S2

2011

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Preferential HIV Infection of CCR6+ Th17 Cells Is Associated with Higher Levels of Virus Receptor Expression and Lack of CCR5 Ligands

Journal of Virology, 2013-10, Vol.87 (19), p.10843-10854

2013

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Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120

Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (10), p.2443-2448

2018

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

Nature, 2007-02, Vol.445 (7129), p.732-737

2007

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Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay

Scientific reports, 2023-12, Vol.13 (1), p.23025-23025, Article 23025

2023

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integrin α₄β₇ forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20877-20882

2009

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TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo

Nature communications, 2024-02, Vol.15 (1), p.1348-1348

2024

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

Science (American Association for the Advancement of Science), 2009-11, Vol.326 (5956), p.1123-1127

2009

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Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes

PLoS pathogens, 2020-12, Vol.16 (12), p.e1009185

2020

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Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques

PLoS pathogens, 2019-05, Vol.15 (5), p.e1007776-e1007776

2019

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HIV-1 subtype C transmitted founders modulate dendritic cell inflammatory responses

Retrovirology, 2020-07, Vol.17 (1), p.1-17, Article 17

2020

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HIV-1 gp120 inhibits TLR9-mediated activation and IFN-α secretion in plasmacytoid dendritic cells

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (9), p.3396-3401

2007

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The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission

PLoS pathogens, 2011-02, Vol.7 (2), p.e1001301-e1001301

2011

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The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

Nature immunology, 2013-12, Vol.14 (12), p.1256

2013

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Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage

eLife, 2024-03, Vol.12

2024

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Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids

PloS one, 2011-09, Vol.6 (9), p.e24559-e24559

2011

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Evidence of recurrent selection of mutations commonly found in SARS-CoV-2 variants of concern in viruses infecting immunocompromised patients

Frontiers in microbiology, 2022-07, Vol.13, p.946549-946549

2022

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HIV-1 gp120: A Target for Therapeutics and Vaccine Design

Current drug targets, 2016-01, Vol.17 (1), p.122

2016

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HIV-1 targets L-selectin for adhesion and induces its shedding for viral release

Nature communications, 2018-07, Vol.9 (1), p.2825-15, Article 2825

2018

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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10

Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV

Preferential HIV Infection of CCR6+ Th17 Cells Is Associated with Higher Levels of Virus Receptor Expression and Lack of CCR5 Ligands

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay

integrin α₄β₇ forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes

Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques

HIV-1 subtype C transmitted founders modulate dendritic cell inflammatory responses

HIV-1 gp120 inhibits TLR9-mediated activation and IFN-α secretion in plasmacytoid dendritic cells

The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression

Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage

Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids

MAdCAM-1 costimulation in the presence of retinoic acid and TGF-β promotes HIV infection and differentiation of CD4+ T cells into CCR5+ TRM-like cells

Evidence of recurrent selection of mutations commonly found in SARS-CoV-2 variants of concern in viruses infecting immunocompromised patients

HIV-1 gp120: A Target for Therapeutics and Vaccine Design

HIV-1 targets L-selectin for adhesion and induces its shedding for viral release

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