UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

The role of kinetic context in apparent biased agonism at GPCRs

Nature communications, 2016-02, Vol.7 (1), p.10842-10842, Article 10842

2016

Volltextzugriff (PDF)

Biased Agonism at G Protein-Coupled Receptors: The Promise and the Challenges-A Medicinal Chemistry Perspective

Medicinal research reviews, 2014-11, Vol.34 (6), p.1286-1330

2014

Volltextzugriff (PDF)

A new mechanism of allostery in a G protein-coupled receptor dimer

Nature chemical biology, 2014-09, Vol.10 (9), p.745-752

2014

Volltextzugriff (PDF)

Design Strategies for Bivalent Ligands Targeting GPCRs

ChemMedChem, 2011-06, Vol.6 (6), p.963-974

2011

Volltextzugriff (PDF)

A Structure–Activity Analysis of Biased Agonism at the Dopamine D2 Receptor

Journal of medicinal chemistry, 2013-11, Vol.56 (22), p.9199-9221

2013

Volltextzugriff (PDF)

Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-04, Vol.14 (1), p.2138-2138, Article 2138

2023

Volltextzugriff (PDF)

Author Correction: Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-05, Vol.14 (1), p.2992-2992, Article 2992

2023

Volltextzugriff (PDF)

GPCR crystal structures: Medicinal chemistry in the pocket

Bioorganic & medicinal chemistry, 2015-07, Vol.23 (14), p.3880-3906

2015

Volltextzugriff (PDF)

Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β‑Arrestin-Biased D2R Agonists

Journal of medicinal chemistry, 2017-06, Vol.60 (11), p.4693-4713

2017

Volltextzugriff (PDF)

Structure–Activity Study of N‑((trans)‑4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)‑yl)ethyl)cyclohexyl)‑1H‑indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a Negative Allosteric Modulator of the Dopamine D2 Receptor

Journal of medicinal chemistry, 2015-07, Vol.58 (13), p.5287-5307

2015

Volltextzugriff (PDF)

Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole

ACS chemical biology, 2019-08, Vol.14 (8), p.1780-1792

2019

Volltextzugriff (PDF)

Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β-Arrestin-Biased D 2 R Agonists

Journal of medicinal chemistry, 2017-06, Vol.60 (11), p.4693-4713

2017

Volltextzugriff (PDF)

8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

Chemistry : a European journal, 2018-02, Vol.24 (8), p.1922-1930

2018

Volltextzugriff (PDF)

The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D2 receptor

Biochemical pharmacology, 2018-02, Vol.148, p.315-328

2018

Volltextzugriff (PDF)

Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.6819-6843

2015

Volltextzugriff (PDF)

The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions

Scientific reports, 2018-01, Vol.8 (1), p.1-12, Article 1208

2018

Volltextzugriff (PDF)

Novel adenosine A2A receptor ligands: A synthetic, functional and computational investigation of selected literature adenosine A2A receptor antagonists for extending into extracellular space

Bioorganic & medicinal chemistry letters, 2013-06, Vol.23 (11), p.3427-3433

2013

Volltextzugriff (PDF)

Structure–Activity Study of N -(( trans )-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1 H )-yl)ethyl)cyclohexyl)-1 H -indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a Negative Allosteric Modulator of the Dopamine D 2 Receptor

Journal of medicinal chemistry, 2015-07, Vol.58 (13), p.5287-5307

2015

Volltextzugriff (PDF)

Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space

Bioorganic & medicinal chemistry letters, 2013-06, Vol.23 (11), p.3427-3433

2013

Volltextzugriff (PDF)

Author Correction: Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-05, Vol.14 (1), p.2992

2023

Volltextzugriff (PDF)

Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-04, Vol.14 (1), p.2138

2023

Volltextzugriff (PDF)

Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D 2 Receptor Through Fragmentation of a Bitopic Ligand

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.6819-6843

2015

Volltextzugriff (PDF)

The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D 2 receptor

Biochemical pharmacology, 2018-02, Vol.148, p.315-328

2018

Volltextzugriff (PDF)

Synthesis, functional and binding profile of (R)-apomorphine based homobivalent ligands targeting the dopamine D2 receptorElectronic supplementary information (ESI) available: Details of chemical synthesis for remaining bivalent ligands (7c-h), and all details of pharmacological analysis including dose-response curves for functional and binding assays. See DOI: 10.1039/c3md00154g

2013-08

Volltextzugriff (PDF)

The action of a negative allosteric modulator at the dopamine D 2 receptor is dependent upon sodium ions

Scientific reports, 2018-01, Vol.8 (1), p.1208

2018

Volltextzugriff (PDF)

1 – 25 von 26

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(25)
Mit Volltextzugriff
(25)

Publikationsform

Artikel
(26)

Sprache

Englisch
(26)
Japanisch
(6)

Erscheinungsjahr

n.n

Thema

Science & Technology
(14)
Humans
(11)
Life Sciences & Biomedicine
(11)
Ligands
(10)
Animals
(9)
Pharmacology & Pharmacy
(9)
Chemistry, Medicinal
(8)
Receptors, Dopamine D2 - Metabolism
(8)
Binding Sites
(7)
Cho Cells
(7)
Cricetulus
(7)
Indoles - Chemistry
(5)
Isoquinolines - Chemistry
(5)
Isoquinolines - Pharmacology
(5)
Protein Conformation
(5)
Chemistry
(4)
Indoles - Pharmacology
(4)
Protein Binding
(4)
Receptors, Dopamine D2 - Chemistry
(4)
Receptors, G-Protein-Coupled - Metabolism
(4)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

The role of kinetic context in apparent biased agonism at GPCRs

Biased Agonism at G Protein-Coupled Receptors: The Promise and the Challenges-A Medicinal Chemistry Perspective

A new mechanism of allostery in a G protein-coupled receptor dimer

Design Strategies for Bivalent Ligands Targeting GPCRs

A Structure–Activity Analysis of Biased Agonism at the Dopamine D2 Receptor

Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Author Correction: Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

GPCR crystal structures: Medicinal chemistry in the pocket

Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β‑Arrestin-Biased D2R Agonists

Structure–Activity Study of N‑((trans)‑4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)‑yl)ethyl)cyclohexyl)‑1H‑indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a Negative Allosteric Modulator of the Dopamine D2 Receptor

Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole

Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β-Arrestin-Biased D 2 R Agonists

8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D2 receptor

Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand

The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions

Novel adenosine A2A receptor ligands: A synthetic, functional and computational investigation of selected literature adenosine A2A receptor antagonists for extending into extracellular space

Structure–Activity Study of N -(( trans )-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1 H )-yl)ethyl)cyclohexyl)-1 H -indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a Negative Allosteric Modulator of the Dopamine D 2 Receptor

Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space

Author Correction: Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D 2 Receptor Through Fragmentation of a Bitopic Ligand

The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D 2 receptor

The action of a negative allosteric modulator at the dopamine D 2 receptor is dependent upon sodium ions

Suchergebnisse filtern