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Prevention of tuberculosis in macaques after intravenous BCG immunization

Nature (London), 2020-01, Vol.577 (7788), p.95

2020

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MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection

PLoS pathogens, 2020-05, Vol.16 (5), p.e1008585-e1008585

2020

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Defining a core breath profile for healthy, non-human primates

Scientific reports, 2024-07, Vol.14 (1), p.17031-9, Article 17031

2024

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Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas

mBio, 2023-06, Vol.14 (3), p.e0047723

2023

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Distributable, metabolic PET reporting of tuberculosis

Nature communications, 2024-06, Vol.15 (1), p.5239-19, Article 5239

2024

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Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens

PLoS computational biology, 2023-06, Vol.19 (6), p.e1010823-e1010823

2023

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Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production

The Journal of clinical investigation, 2005-06, Vol.115 (6), p.1601-1606

2005

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Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques

The Journal of immunology (1950), 2017-02, Vol.198 (4), p.1616-1626

2017

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Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes

Frontiers in immunology, 2017-05, Vol.8, p.542-542

2017

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Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis

Microbiology spectrum, 2022-06, Vol.10 (3), p.e0172421-e0172421

2022

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MyD88-Deficient Mice Display a Profound Loss in Resistance to Mycobacterium tuberculosis Associated with Partially Impaired Th1 Cytokine and Nitric Oxide Synthase 2 Expression

Infection and Immunity, 2004-04, Vol.72 (4), p.2400-2404

2004

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Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection

The Journal of immunology (1950), 2016-09, Vol.197 (5), p.1852-1863

2016

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Effects of Tumor Necrosis Factor Alpha on Host Immune Response in Chronic Persistent Tuberculosis: Possible Role for Limiting Pathology

Infection and Immunity, 2001-03, Vol.69 (3), p.1847-1855

2001

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Modeling tuberculosis in nonhuman primates

Cold Spring Harbor perspectives in medicine, 2014-12, Vol.4 (12), p.a018564-a018564

2014

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Antibody glycosylation correlates with disease progression in SIV- Mycobacterium tuberculosis coinfected cynomolgus macaques

Clinical & translational immunology, 2023, Vol.12 (11), p.e1474-e1474

2023

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Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison

Infection and immunity, 2018-02, Vol.86 (2)

2018

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Maintenance of Pulmonary Th1 Effector Function in Chronic Tuberculosis Requires Persistent IL-12 Production

The Journal of immunology (1950), 2005-04, Vol.174 (7), p.4185-4192

2005

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Influence of Coinfecting Pathogens on HIV Expression: Evidence for a Role of Toll-Like Receptors

The Journal of immunology (1950), 2004-06, Vol.172 (12), p.7229-7234

2004

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Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Immunity (Cambridge, Mass.), 2022-05, Vol.55 (5), p.827-846.e10

2022

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TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis

The Journal of experimental medicine, 2005-12, Vol.202 (12), p.1715-1724

2005

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The Inducible Nitric Oxide Synthase Locus Confers Protection against Aerogenic Challenge of Both Clinical and Laboratory Strains of Mycobacterium tuberculosis in Mice

Infection and Immunity, 2001-12, Vol.69 (12), p.7711-7717

2001

Volltextzugriff (PDF)

Evaluating the effect of clofazimine against Mycobacterium tuberculosis given alone or in combination with pretomanid, bedaquiline or linezolid

International journal of antimicrobial agents, 2022-02, Vol.59 (2), p.106509-106509, Article 106509

2022

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Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques

Cell host & microbe, 2023-06, Vol.31 (6), p.962-977.e8

2023

Volltextzugriff (PDF)

Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge

The Journal of immunology (1950), 2014-08, Vol.193 (4), p.1799-1811

2014

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Prevention of tuberculosis in macaques after intravenous BCG immunization

MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection

Defining a core breath profile for healthy, non-human primates

Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas

Distributable, metabolic PET reporting of tuberculosis

Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens

Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production

Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques

Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes

Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis

MyD88-Deficient Mice Display a Profound Loss in Resistance to Mycobacterium tuberculosis Associated with Partially Impaired Th1 Cytokine and Nitric Oxide Synthase 2 Expression

Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection

Effects of Tumor Necrosis Factor Alpha on Host Immune Response in Chronic Persistent Tuberculosis: Possible Role for Limiting Pathology

Modeling tuberculosis in nonhuman primates

Antibody glycosylation correlates with disease progression in SIV- Mycobacterium tuberculosis coinfected cynomolgus macaques

Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison

Maintenance of Pulmonary Th1 Effector Function in Chronic Tuberculosis Requires Persistent IL-12 Production

Influence of Coinfecting Pathogens on HIV Expression: Evidence for a Role of Toll-Like Receptors

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis

The Inducible Nitric Oxide Synthase Locus Confers Protection against Aerogenic Challenge of Both Clinical and Laboratory Strains of Mycobacterium tuberculosis in Mice

Evaluating the effect of clofazimine against Mycobacterium tuberculosis given alone or in combination with pretomanid, bedaquiline or linezolid

Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques

Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge

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