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Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

Nature medicine, 2014-01, Vol.20 (1), p.75-79

2014

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Persisters and beyond: Mechanisms of phenotypic drug resistance and drug tolerance in bacteria

Critical reviews in biochemistry and molecular biology, 2014-03, Vol.49 (2), p.91-101

2014

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Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

Science (American Association for the Advancement of Science), 2012-01, Vol.335 (6064), p.100-104

2012

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Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

Nature genetics, 2013-07, Vol.45 (7), p.784-790

2013

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TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities

PLoS pathogens, 2018-03, Vol.14 (3), p.e1006939

2018

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The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome

mBio, 2016-04, Vol.7 (2), p.e00342-e00316

2016

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Efferocytosis Is an Innate Antibacterial Mechanism

Cell host & microbe, 2012-09, Vol.12 (3), p.289-300

2012

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Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape

PLoS genetics, 2015-11, Vol.11 (11), p.e1005641-e1005641

2015

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Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization

PLoS pathogens, 2015-01, Vol.11 (1), p.e1004603-e1004603

2015

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DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis

PLoS pathogens, 2013-07, Vol.9 (7), p.e1003419

2013

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Evidence of molting and the function of "rock-nosing" behavior in bowhead whales in the eastern Canadian Arctic

PloS one, 2017-11, Vol.12 (11), p.e0186156-e0186156

2017

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NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

PLoS pathogens, 2009-07, Vol.5 (7), p.e1000500-e1000500

2009

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Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria

PLoS pathogens, 2015-06, Vol.11 (6), p.e1005010-e1005010

2015

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Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques

PLoS pathogens, 2018-10, Vol.14 (10), p.e1007305-e1007305

2018

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Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

PLoS pathogens, 2018-05, Vol.14 (5), p.e1007060-e1007060

2018

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Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

Nature microbiology, 2017-02, Vol.2, p.16274

2017

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PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

PLoS pathogens, 2016-07, Vol.12 (7), p.e1005739-e1005739

2016

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Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

Nature genetics, 2011-05, Vol.43 (5), p.482-486

2011

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Bowhead whales use two foraging strategies in response to fine-scale differences in zooplankton vertical distribution

Scientific reports, 2020-11, Vol.10 (1), p.20249-20249, Article 20249

2020

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Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis

mBio, 2019-04, Vol.10 (2)

2019

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Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis

PLoS pathogens, 2022-07, Vol.18 (7), p.e1010705-e1010705

2022

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Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure

PLoS pathogens, 2024-02, Vol.20 (2), p.e1012050-e1012050

2024

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Genetically encoded transcriptional plasticity underlies stress adaptation in Mycobacterium tuberculosis

Nature communications, 2024-04, Vol.15 (1), p.3088-3088

2024

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Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis

Nature communications, 2019-05, Vol.10 (1), p.2329-2329, Article 2329

2019

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Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (44), p.18792-18797

2009

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Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

Persisters and beyond: Mechanisms of phenotypic drug resistance and drug tolerance in bacteria

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities

The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome

Efferocytosis Is an Innate Antibacterial Mechanism

Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape

Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization

DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis

Evidence of molting and the function of "rock-nosing" behavior in bowhead whales in the eastern Canadian Arctic

NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria

Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques

Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

Bowhead whales use two foraging strategies in response to fine-scale differences in zooplankton vertical distribution

Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis

Loss of RNase J leads to multi-drug tolerance and accumulation of highly structured mRNA fragments in Mycobacterium tuberculosis

Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure

Genetically encoded transcriptional plasticity underlies stress adaptation in Mycobacterium tuberculosis

Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

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