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Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2019-07, Vol.22 (4), p.828-837

2019

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Discovery of MK-8719, a Potent O‑GlcNAcase Inhibitor as a Potential Treatment for Tauopathies

Journal of medicinal chemistry, 2019-11, Vol.62 (22), p.10062-10097

2019

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Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy

PloS one, 2018-04, Vol.13 (4), p.e0195486-e0195486

2018

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The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review

Alzheimer's & dementia, 2018-10, Vol.14 (10), p.1313-1333

2018

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Cerebrospinal fluid biomarkers distinguish postmortem-confirmed Alzheimer's disease from other dementias and healthy controls in the OPTIMA cohort

Journal of Alzheimer's disease, 2015-01, Vol.44 (2), p.525

2015

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Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans

Drug metabolism and disposition, 2015-06, Vol.43 (6), p.851-863

2015

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AMPA Receptor Downscaling at the Onset of Alzheimer's Disease Pathology in Double Knockin Mice

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (9), p.3410-3415

2006

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Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression

PloS one, 2015-12, Vol.10 (12), p.e0145151-e0145151

2015

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Characterization of plasma β-secretase (BACE1) activity and soluble amyloid precursor proteins as potential biomarkers for Alzheimer's disease

Journal of neuroscience research, 2012-12, Vol.90 (12), p.2247-2258

2012

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Soluble BACE-1 Activity and sAβPPβ Concentrations in Alzheimer's Disease and Age-Matched Healthy Control Cerebrospinal Fluid from the Alzheimer's Disease Neuroimaging Initiative-1 Baseline Cohort

Journal of Alzheimer's disease, 2015-01, Vol.46 (2), p.431

2015

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CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition

The Journal of neuroscience, 2014-06, Vol.34 (24), p.8336-8346

2014

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Activation of c-Jun N-Terminal Kinase and p38 in an Alzheimer's Disease Model Is Associated with Amyloid Deposition

The Journal of neuroscience, 2002-05, Vol.22 (9), p.3376-3385

2002

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A Machine Learning Approach to Identify a Circulating MicroRNA Signature for Alzheimer Disease

The journal of applied laboratory medicine, 2020-01, Vol.5 (1), p.15-28

2020

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Systems Pharmacology Analysis of the Amyloid Cascade after β-Secretase Inhibition Enables the Identification of an Aβ42 Oligomer Pool

The Journal of pharmacology and experimental therapeutics, 2016-04, Vol.357 (1), p.205

2016

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Pyroglutamate-Modified Amyloid-β Protein Demonstrates Similar Properties in an Alzheimer's Disease Familial Mutant Knock-In Mouse and Alzheimer's Disease Brain

Neuro-degenerative diseases, 2014-01, Vol.14 (2), p.53-66

2014

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A transgenic rat model of Alzheimer's disease with extracellular Aβ deposition

Neurobiology of aging, 2009-07, Vol.30 (7), p.1078-1090

2009

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Advances in the development of kinase inhibitor therapeutics for Alzheimer's disease

Drug development research, 2009-03, Vol.70 (2), p.125-144

2009

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Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease

Neurobiology of aging, 2006-03, Vol.27 (3), p.377-386

2006

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Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase

Bioorganic & medicinal chemistry letters, 2014-06, Vol.24 (12), p.2737-2740

2014

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Abeta oligomers as a pharmacodynamic biomarker of secretase therapy in Alzheimer's disease?

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P325-P325

2015

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Cerebrospinal fluid amyloid oligomers measured in a subset of the aibl and optima age-matched healthy control and Alzheimer’s cohorts

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P305-P306

2015

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FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development

Science (American Association for the Advancement of Science), 1994-04, Vol.264 (5155), p.104-107

1994

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Clinical Utility of the Combined Positive Score for Programmed Death Ligand-1 Expression and the Approval of Pembrolizumab for Treatment of Gastric Cancer

First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study

Long-Term Outcomes in KEYNOTE-052: Phase II Study Investigating First-Line Pembrolizumab in Cisplatin-Ineligible Patients With Locally Advanced or Metastatic Urothelial Cancer

Pembrolizumab alone or in combination with chemotherapy as first-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma: results from the phase II nonrandomized KEYNOTE-059 study

Discovery of MK-8719, a Potent O‑GlcNAcase Inhibitor as a Potential Treatment for Tauopathies

Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review

Cerebrospinal fluid biomarkers distinguish postmortem-confirmed Alzheimer's disease from other dementias and healthy controls in the OPTIMA cohort

Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans

AMPA Receptor Downscaling at the Onset of Alzheimer's Disease Pathology in Double Knockin Mice

Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression

Characterization of plasma β-secretase (BACE1) activity and soluble amyloid precursor proteins as potential biomarkers for Alzheimer's disease

Soluble BACE-1 Activity and sAβPPβ Concentrations in Alzheimer's Disease and Age-Matched Healthy Control Cerebrospinal Fluid from the Alzheimer's Disease Neuroimaging Initiative-1 Baseline Cohort

CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition

Activation of c-Jun N-Terminal Kinase and p38 in an Alzheimer's Disease Model Is Associated with Amyloid Deposition

A Machine Learning Approach to Identify a Circulating MicroRNA Signature for Alzheimer Disease

Systems Pharmacology Analysis of the Amyloid Cascade after β-Secretase Inhibition Enables the Identification of an Aβ42 Oligomer Pool

Pyroglutamate-Modified Amyloid-β Protein Demonstrates Similar Properties in an Alzheimer's Disease Familial Mutant Knock-In Mouse and Alzheimer's Disease Brain

A transgenic rat model of Alzheimer's disease with extracellular Aβ deposition

Advances in the development of kinase inhibitor therapeutics for Alzheimer's disease

Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease

Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase

Abeta oligomers as a pharmacodynamic biomarker of secretase therapy in Alzheimer's disease?

Cerebrospinal fluid amyloid oligomers measured in a subset of the aibl and optima age-matched healthy control and Alzheimer’s cohorts

FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development

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