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BRCA1, a ‘complex’ protein involved in the maintenance of genomic stability

The FEBS journal, 2015-02, Vol.282 (4), p.630-646

2015

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Use of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures

PloS one, 2013-11, Vol.8 (11), p.e79541

2013

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‘From R-lupus to cancer’: Reviewing the role of R-loops in innate immune responses

DNA repair, 2023-11, Vol.131, p.103581-103581, Article 103581

2023

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Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Molecular cell, 2014-05, Vol.54 (3), p.445-459

2014

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Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer

JNCI : Journal of the National Cancer Institute, 2017-01, Vol.109 (1), p.djw199

2017

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The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export

Nucleic acids research, 2017-12, Vol.45 (22), p.12816-12833

2017

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Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors

Cancer research (Chicago, Ill.), 2022-03, Vol.82 (5), p.819-830

2022

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Homologous recombination deficiency in breast cancer: Implications for risk, cancer development, and therapy

Genes chromosomes & cancer, 2021-05, Vol.60 (5), p.358-372

2021

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The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

Cell reports (Cambridge), 2015-04, Vol.11 (1), p.149-163

2015

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The DNA damage induced immune response: Implications for cancer therapy

DNA repair, 2022-12, Vol.120, p.103409-103409, Article 103409

2022

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Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability

Scientific reports, 2019-02, Vol.9 (1), p.2678-2678, Article 2678

2019

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BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability

Cancer research (Chicago, Ill.), 2014-05, Vol.74 (10), p.2773-2784

2014

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ACE: A Workbench Using Evolutionary Genetic Algorithms for Analyzing Association in TCGA

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (8), p.2072-2075

2019

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Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

Journal of translational medicine, 2020-09, Vol.18 (1), p.339-339, Article 339

2020

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BRD7, a Subunit of SWI/SNF Complexes, Binds Directly to BRCA1 and Regulates BRCA1-Dependent Transcription

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2538-2547

2010

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Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM

Cancer research (Chicago, Ill.), 2015-06, Vol.75 (11), p.2159-2165

2015

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Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer

British journal of cancer, 2022-02, Vol.126 (2), p.247-258

2022

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Dual roles of DNA repair enzymes in RNA biology/post-transcriptional control

Wiley interdisciplinary reviews. RNA, 2016-09, Vol.7 (5), p.604-619

2016

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Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers

The journal of pathology. Clinical research, 2020-04, Vol.6 (2), p.146-153

2020

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Protein kinase C zeta suppresses low‐ or high‐grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring

The Journal of pathology, 2018-04, Vol.244 (4), p.445-459

2018

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Krüppel-associated Box (KRAB)-associated Co-repressor (KAP-1) Ser-473 Phosphorylation Regulates Heterochromatin Protein 1β (HP1-β) Mobilization and DNA Repair in Heterochromatin

The Journal of biological chemistry, 2012-08, Vol.287 (33), p.28122-28131

2012

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Robust automated tumour segmentation on histological and immunohistochemical tissue images

PloS one, 2011-02, Vol.6 (2), p.e15818-e15818

2011

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Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis

Nucleic acids research, 2011-12, Vol.39 (22), p.9536-9548

2011

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Targeting nucleotide metabolism enhances the efficacy of anthracyclines and anti-metabolites in triple-negative breast cancer

NPJ breast cancer, 2021-04, Vol.7 (1), p.38-38, Article 38

2021

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hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

Nucleic acids research, 2011-03, Vol.39 (5), p.1692-1702

2011

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BRCA1, a ‘complex’ protein involved in the maintenance of genomic stability

Use of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures

‘From R-lupus to cancer’: Reviewing the role of R-loops in innate immune responses

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors

Homologous recombination deficiency in breast cancer: Implications for risk, cancer development, and therapy

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

The DNA damage induced immune response: Implications for cancer therapy

Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability

BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability

ACE: A Workbench Using Evolutionary Genetic Algorithms for Analyzing Association in TCGA

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

BRD7, a Subunit of SWI/SNF Complexes, Binds Directly to BRCA1 and Regulates BRCA1-Dependent Transcription

Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM

Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer

Dual roles of DNA repair enzymes in RNA biology/post-transcriptional control

Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers

Protein kinase C zeta suppresses low‐ or high‐grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring

Krüppel-associated Box (KRAB)-associated Co-repressor (KAP-1) Ser-473 Phosphorylation Regulates Heterochromatin Protein 1β (HP1-β) Mobilization and DNA Repair in Heterochromatin

Robust automated tumour segmentation on histological and immunohistochemical tissue images

Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis

Targeting nucleotide metabolism enhances the efficacy of anthracyclines and anti-metabolites in triple-negative breast cancer

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

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