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Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2023-01, Vol.38 (1), p.203-215

2023

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Sulfadiazine Exerts Potential Anticancer Effect in HepG2 and MCF7 Cells by Inhibiting TNFα, IL1b, COX-1, COX-2, 5-LOX Gene Expression: Evidence from In Vitro and Computational Studies

Pharmaceuticals (Basel, Switzerland), 2024-01, Vol.17 (2), p.189

2024

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Rational Design, Synthesis and Biological Evaluation of Novel Pyrazoline-Based Antiproliferative Agents in MCF-7 Cancer Cells

Pharmaceuticals (Basel, Switzerland), 2022-10, Vol.15 (10), p.1245

2022

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Design, Synthesis, Anticancer Activity, and Solid Lipid Nanoparticle Formulation of Indole- and Benzimidazole-Based Compounds as Pro-Apoptotic Agents Targeting Bcl-2 Protein

Pharmaceuticals (Basel, Switzerland), 2021-02, Vol.14 (2), p.113

2021

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The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme

Pharmaceuticals (Basel, Switzerland), 2020-09, Vol.13 (9), p.252

2020

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Validated Stability-Indicating Reversed-Phase-HPLC Method for Simultaneous Determination of Orphenadrine Citrate, Caffeine and Aspirin

Chemical and Pharmaceutical Bulletin, 2012/11/01, Vol.60(11), pp.1426-1436

2012

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Synthesis, Molecular Modeling, and Biological Evaluation of Novel Benzimidazole Derivatives as Inhibitors of Hepatitis C Virus RNA Replication

Chemical and Pharmaceutical Bulletin, 2014/09/01, Vol.62(9), pp.856-866

2014

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Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors

ChemistryOpen (Weinheim), 2019-07, Vol.8 (7), p.995-1011

2019

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Simultaneous HPLC–UV analysis of telmisartan and hydrochlorothiazide in human plasma

Bulletin of the Faculty of Pharmacy, 2011-06, Vol.49 (1), p.19-24

Salama, Ismail

2011

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A Stability-indicating HPLC Method for the Simultaneous Determination of Mebeverine Hydrochloride and Chlordiazepoxide in Commercial Tablets

Current analytical chemistry, 2014-01, Vol.10 (4), p.565-573

2014

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Development and Validation of a UPLC–MS/MS Method for the Simultaneous Determination of Telmisartan and Metformine HCl in Human Plasma

Current analytical chemistry, 2015-01, Vol.11 (2), p.130-137

2015

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دور المشروعات الصغيرة في تحقيق التنمية الاقتصادية في فلسطين

Dirāsāt. ʻUlūm al-insānīyah wa-al-ijtimāʻīyah., 2024-06, Vol.51 (3), p.14-28

2024

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Liquid chromatography tandem mass spectrometry for the simultaneous determination of metformin and pioglitazone in rat plasma: Application to pharmacokinetic and drug-drug interaction studies

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019-08, Vol.1124, p.47-57

2019

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Design, synthesis, and in‐silico study of novel triarylethylene analogs with dual anti‐estrogenic and serotonergic activity

Drug development research, 2024-02, Vol.85 (1), p.e22127-n/a

2024

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Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents

European journal of medicinal chemistry, 2017-09, Vol.138, p.698-714

2017

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Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARγ/FFAR1 dual agonists

European journal of medicinal chemistry, 2016-02, Vol.109, p.157-172

2016

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Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists

Bioorganic & medicinal chemistry letters, 2018-05, Vol.28 (9), p.1595-1602

2018

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Comparative High-Performance Liquid Chromatographic and High-Performance Thin-Layer Chromatographic Study for the Simultaneous Determination of Dapagliflozin and Metformin Hydrochloride in Bulk and Pharmaceutical Formulation

JPC. Journal of planar chromatography, modern TLC, 2018-12, Vol.31 (6), p.469-476

2018

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CoMFA and CoMSIA studies of 1,2-dihydropyridine derivatives as anticancer agents

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2012-05, Vol.8 (3), p.372-383

2012

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Synthesis and binding profile of haloperidol-based bivalent ligands targeting dopamine D2-like receptors

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (16), p.3753-3756

2014

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1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (18), p.6195-6209

2015

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4-azido-7-nitrobenzoxadiazole as Innovative Clickable Fluorescence Probe for Trace and Selective Quantification of Ethinylestradiol in Human Plasma

Luminescence (Chichester, England), 2023-11, Vol.38 (11), p.1848-1856

2023

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Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo[3,4–d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study

Bioorganic chemistry, 2022-12, Vol.129, p.106207, Article 106207

2022

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Novel fluorescence approach for trace quantification of levonorgestrel in breast milk based on click reaction with benzonitrofurazan azide (NBD-AZ)

Methods and applications in fluorescence, 2024-01, Vol.12 (1), p.15009

2024

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Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (8), p.1546-1561

2019

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Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors

Sulfadiazine Exerts Potential Anticancer Effect in HepG2 and MCF7 Cells by Inhibiting TNFα, IL1b, COX-1, COX-2, 5-LOX Gene Expression: Evidence from In Vitro and Computational Studies

Rational Design, Synthesis and Biological Evaluation of Novel Pyrazoline-Based Antiproliferative Agents in MCF-7 Cancer Cells

Design, Synthesis, Anticancer Activity, and Solid Lipid Nanoparticle Formulation of Indole- and Benzimidazole-Based Compounds as Pro-Apoptotic Agents Targeting Bcl-2 Protein

The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme

Validated Stability-Indicating Reversed-Phase-HPLC Method for Simultaneous Determination of Orphenadrine Citrate, Caffeine and Aspirin

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Benzimidazole Derivatives as Inhibitors of Hepatitis C Virus RNA Replication

Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors

Simultaneous HPLC–UV analysis of telmisartan and hydrochlorothiazide in human plasma

A Stability-indicating HPLC Method for the Simultaneous Determination of Mebeverine Hydrochloride and Chlordiazepoxide in Commercial Tablets

Development and Validation of a UPLC–MS/MS Method for the Simultaneous Determination of Telmisartan and Metformine HCl in Human Plasma

دور المشروعات الصغيرة في تحقيق التنمية الاقتصادية في فلسطين

Liquid chromatography tandem mass spectrometry for the simultaneous determination of metformin and pioglitazone in rat plasma: Application to pharmacokinetic and drug-drug interaction studies

Design, synthesis, and in‐silico study of novel triarylethylene analogs with dual anti‐estrogenic and serotonergic activity

Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents

Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARγ/FFAR1 dual agonists

Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists

Comparative High-Performance Liquid Chromatographic and High-Performance Thin-Layer Chromatographic Study for the Simultaneous Determination of Dapagliflozin and Metformin Hydrochloride in Bulk and Pharmaceutical Formulation

CoMFA and CoMSIA studies of 1,2-dihydropyridine derivatives as anticancer agents

Synthesis and binding profile of haloperidol-based bivalent ligands targeting dopamine D2-like receptors

1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation

4-azido-7-nitrobenzoxadiazole as Innovative Clickable Fluorescence Probe for Trace and Selective Quantification of Ethinylestradiol in Human Plasma

Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo[3,4–d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study

Novel fluorescence approach for trace quantification of levonorgestrel in breast milk based on click reaction with benzonitrofurazan azide (NBD-AZ)

Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1

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