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X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability

Science (American Association for the Advancement of Science), 2015-07, Vol.349 (6243), p.99-103

2015

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HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

Nature communications, 2020-07, Vol.11 (1), p.3505-3505, Article 3505

2020

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Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry That Act by Three Distinct Mechanisms

Journal of Virology, 2013-07, Vol.87 (14), p.8017-8028

2013

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Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication

Nucleic acids research, 2022-02, Vol.50 (3), p.1701

2022

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The HIV-1 capsid core is an opportunistic nuclear import receptor

Nature communications, 2023-06, Vol.14 (1), p.3782-3782, Article 3782

2023

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Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

Journal of molecular biology, 2009-01, Vol.385 (3), p.693-713

2009

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The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes

PLoS pathogens, 2013-01, Vol.9 (1), p.e1003125-e1003125

2013

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Mechanism of nucleic acid unwinding by SARS-CoV helicase

PloS one, 2012-05, Vol.7 (5), p.e36521-e36521

2012

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Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein

International journal of molecular sciences, 2024-04, Vol.25 (7), p.3734

2024

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Rotten to the core: antivirals targeting the HIV-1 capsid core

Retrovirology, 2021-12, Vol.18 (1), p.41-24, Article 41

2021

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Long-Acting Anti-HIV Drugs Targeting HIV-1 Reverse Transcriptase and Integrase

Pharmaceuticals (Basel, Switzerland), 2019-04, Vol.12 (2), p.62

2019

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Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (33), p.9274-9279

2016

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Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.5051-5062

2016

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Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase

Microorganisms (Basel), 2021-04, Vol.9 (5), p.893

2021

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Specific mutations in the HIV-1 G-tract of the 3′-polypurine tract cause resistance to integrase strand transfer inhibitors

Journal of antimicrobial chemotherapy, 2022-02, Vol.77 (3), p.574-577

2022

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Multiplex single-cell visualization of nucleic acids and protein during HIV infection

Nature communications, 2017-12, Vol.8 (1), p.1882-11, Article 1882

2017

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Severe Acute Respiratory Syndrome Coronavirus Replication Inhibitor That Interferes with the Nucleic Acid Unwinding of the Viral Helicase

Antimicrobial Agents and Chemotherapy, 2012-09, Vol.56 (9), p.4718-4728

2012

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Effect of P‐body component Mov10 on HCV virus production and infectivity

The FASEB journal, 2020-07, Vol.34 (7), p.9433-9449

2020

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Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque

Antimicrobial agents and chemotherapy, 2015-07, Vol.59 (7), p.4190-4198

2015

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Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization

Nature communications, 2023-09, Vol.14 (1), p.5614-5614, Article 5614

2023

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Drug Interactions in Lenacapavir-Based Long-Acting Antiviral Combinations

Viruses, 2022-05, Vol.14 (6), p.1202

2022

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Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation

Viruses, 2021-05, Vol.13 (5), p.920

2021

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Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H

Accounts of chemical research, 2020-01, Vol.53 (1), p.218-230

2020

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Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches

Viruses, 2021-04, Vol.13 (5), p.770

2021

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Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and Their Interactions with the M184I Mutation on Defining Patterns of Resistance to Nonnucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine

Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3100-3109

2013

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X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry That Act by Three Distinct Mechanisms

Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication

The HIV-1 capsid core is an opportunistic nuclear import receptor

Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes

Mechanism of nucleic acid unwinding by SARS-CoV helicase

Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein

Rotten to the core: antivirals targeting the HIV-1 capsid core

Long-Acting Anti-HIV Drugs Targeting HIV-1 Reverse Transcriptase and Integrase

Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)

Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H

Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase

Specific mutations in the HIV-1 G-tract of the 3′-polypurine tract cause resistance to integrase strand transfer inhibitors

Multiplex single-cell visualization of nucleic acids and protein during HIV infection

Severe Acute Respiratory Syndrome Coronavirus Replication Inhibitor That Interferes with the Nucleic Acid Unwinding of the Viral Helicase

Effect of P‐body component Mov10 on HCV virus production and infectivity

Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization

Drug Interactions in Lenacapavir-Based Long-Acting Antiviral Combinations

Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation

Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H

Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches

Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and Their Interactions with the M184I Mutation on Defining Patterns of Resistance to Nonnucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine

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