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HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

PLoS pathogens, 2011-12, Vol.7 (12), p.e1002439-e1002439

2011

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X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability

Science (American Association for the Advancement of Science), 2015-07, Vol.349 (6243), p.99-103

2015

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Flexible Use of Nuclear Import Pathways by HIV-1

Cell host & microbe, 2010-03, Vol.7 (3), p.221-233

2010

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CPSF6 defines a conserved capsid interface that modulates HIV-1 replication

PLoS pathogens, 2012-08, Vol.8 (8), p.e1002896-e1002896

2012

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The HIV-1 capsid core is an opportunistic nuclear import receptor

Nature communications, 2023-06, Vol.14 (1), p.3782-3782, Article 3782

2023

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Formation of nuclear CPSF6/CPSF5 biomolecular condensates upon HIV-1 entry into the nucleus is important for productive infection

Scientific reports, 2023-07, Vol.13 (1), p.10974-10974, Article 10974

2023

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Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity

PloS one, 2010-02, Vol.5 (2), p.e9081-e9081

2010

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Structural basis for nuclear import of splicing factors by human Transportin 3

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2728-2733

2014

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A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats

Nature communications, 2022-03, Vol.13 (1), p.1474-1474, Article 1474

2022

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Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration

Journal of Virology, 2013-01, Vol.87 (1), p.648-658

2013

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Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection

Nature communications, 2022-10, Vol.13 (1), p.5879-19, Article 5879

2022

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The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

Journal of Virology, 2010-01, Vol.84 (1), p.397-406

2010

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CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration

mBio, 2020-09, Vol.11 (5)

2020

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HIV-1–induced AIDS in monkeys

Science (American Association for the Advancement of Science), 2014-06, Vol.344 (6190), p.1401-1405

2014

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Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection

Journal of Virology, 2012-04, Vol.86 (8), p.4708-4714

2012

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HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6

Journal of Virology, 2012-04, Vol.86 (7), p.3851-3860

2012

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A single gp120 residue can affect HIV-1 tropism in macaques

PLoS pathogens, 2017-09, Vol.13 (9), p.e1006572-e1006572

2017

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Dendritic-cell interactions with HIV: infection and viral dissemination

Nature Reviews: Immunology, 2006-11, Vol.6 (11), p.859-868

2006

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GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors

iScience, 2022-01, Vol.25 (1), p.103593-103593, Article 103593

2022

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Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities

Nucleic acids research, 2014-02, Vol.42 (3), p.2085

2014

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macaque model of HIV-1 infection

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (11), p.4425-4429

2009

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Selection of Unadapted, Pathogenic SHIVs Encoding Newly Transmitted HIV-1 Envelope Proteins

Cell host & microbe, 2014-09, Vol.16 (3), p.412-418

2014

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Expression cloning of new receptors used by simian and human immunodeficiency viruses

Nature (London), 1997-07, Vol.388 (6639), p.296-300

1997

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Ultrasensitive Allele-Specific PCR Reveals Rare Preexisting Drug-Resistant Variants and a Large Replicating Virus Population in Macaques Infected with a Simian Immunodeficiency Virus Containing Human Immunodeficiency Virus Reverse Transcriptase

Journal of Virology, 2012-12, Vol.86 (23), p.12525-12530

2012

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Antimicrobial Peptides from Amphibian Skin Potently Inhibit Human Immunodeficiency Virus Infection and Transfer of Virus from Dendritic Cells to T Cells

Journal of Virology, 2005-09, Vol.79 (18), p.11598-11606

2005

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HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability

Flexible Use of Nuclear Import Pathways by HIV-1

CPSF6 defines a conserved capsid interface that modulates HIV-1 replication

The HIV-1 capsid core is an opportunistic nuclear import receptor

Formation of nuclear CPSF6/CPSF5 biomolecular condensates upon HIV-1 entry into the nucleus is important for productive infection

Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity

Structural basis for nuclear import of splicing factors by human Transportin 3

A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats

Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration

Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration

HIV-1–induced AIDS in monkeys

Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection

HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6

A single gp120 residue can affect HIV-1 tropism in macaques

Dendritic-cell interactions with HIV: infection and viral dissemination

GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors

Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities

macaque model of HIV-1 infection

Selection of Unadapted, Pathogenic SHIVs Encoding Newly Transmitted HIV-1 Envelope Proteins

Expression cloning of new receptors used by simian and human immunodeficiency viruses

Ultrasensitive Allele-Specific PCR Reveals Rare Preexisting Drug-Resistant Variants and a Large Replicating Virus Population in Macaques Infected with a Simian Immunodeficiency Virus Containing Human Immunodeficiency Virus Reverse Transcriptase

Antimicrobial Peptides from Amphibian Skin Potently Inhibit Human Immunodeficiency Virus Infection and Transfer of Virus from Dendritic Cells to T Cells

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