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A general protocol for the generation of Nanobodies for structural biology

Nature protocols, 2014-03, Vol.9 (3), p.674-693

2014

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Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (31), p.12669-12674

2011

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Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance

Biochimica et biophysica acta, 2015-05, Vol.1848 (5), p.1224-1233

2015

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Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

Journal of molecular biology, 2010-01, Vol.395 (3), p.568-577

2010

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Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV

Structure (London), 2003-08, Vol.11 (8), p.947-959

2003

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Determination of Protein–Ligand Binding Constants of a Cooperatively Regulated Tetrameric Enzyme Using Electrospray Mass Spectrometry

ACS chemical biology, 2014-01, Vol.9 (1), p.218-226

2014

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Crystal structures of the human doublecortin C-terminal and N-terminal domains in complex with specific antibodies

Acta crystallographica. Section A, Foundations and advances, 2016-08, Vol.72 (a1), p.s25-s25

Ruf, Armin

2016

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Inhibitor and NAD+ Binding to Poly(ADP-ribose) Polymerase As Derived from Crystal Structures and Homology Modeling

Biochemistry (Easton), 1998-03, Vol.37 (11), p.3893-3900

1998

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The mechanism of the elongation and branching reaction of Poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis

Journal of molecular biology, 1998-04, Vol.278 (1), p.57-65

1998

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Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases

Chimia, 2015-01, Vol.69 (7-8), p.407

2015

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The monotopic membrane protein human oxidosqualene cyclase is active as monomer

Biochemical and biophysical research communications, 2004-03, Vol.315 (2), p.247-254

2004

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Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

Nature communications, 2012-07, Vol.3 (1), p.936-936, Article 936

2012

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Domain swap in the C‐terminal ubiquitin‐like domain of human doublecortin

Acta crystallographica. Section D, Biological crystallography., 2018-05, Vol.74 (5), p.450-462

2018

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Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase

Acta crystallographica. Section D, Biological crystallography., 2016-11, Vol.72 (11), p.1212-1224

2016

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Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

Nature, 2004-11, Vol.432 (7013), p.118-122

2004

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Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

Journal of molecular biology, 2010-11, Vol.403 (4), p.562-577

2010

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Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design

Journal of molecular biology, 2010-03, Vol.397 (2), p.508-519

2010

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Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery

Fragment-Based Drug Discovery and X-Ray Crystallography, 2012, Vol.317, p.115-143

2012

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A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro

Molecular endocrinology (Baltimore, Md.), 2006-04, Vol.20 (4), p.809-830

2006

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Structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa

Acta crystallographica. Section D, Biological crystallography., 2013-01, Vol.69 (1), p.24-31

2013

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Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

The Journal of biological chemistry, 2016-07, Vol.291 (31), p.16292-16306

2016

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Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes

Bioorganic & medicinal chemistry letters, 2009-05, Vol.19 (9), p.2468-2473

2009

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Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors

ChemMedChem, 2012-06, Vol.7 (6), p.1101-1111

2012

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Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods

Journal of molecular recognition, 2015-08, Vol.28 (8), p.480-491

2015

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Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods: COMPETITION AND ALLOSTERIC MODULATION

Journal of molecular recognition, 2015-08, Vol.28 (8), p.480-491

2015

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A general protocol for the generation of Nanobodies for structural biology

Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance

Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV

Determination of Protein–Ligand Binding Constants of a Cooperatively Regulated Tetrameric Enzyme Using Electrospray Mass Spectrometry

Crystal structures of the human doublecortin C-terminal and N-terminal domains in complex with specific antibodies

Inhibitor and NAD+ Binding to Poly(ADP-ribose) Polymerase As Derived from Crystal Structures and Homology Modeling

The mechanism of the elongation and branching reaction of Poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis

Challenges and Rewards in Medicinal Chemistry Targeting Cardiovascular and Metabolic Diseases

The monotopic membrane protein human oxidosqualene cyclase is active as monomer

Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

Domain swap in the C‐terminal ubiquitin‐like domain of human doublecortin

Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design

Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery

A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro

Structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa

Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies

Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes

Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors

Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods

Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods: COMPETITION AND ALLOSTERIC MODULATION

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