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Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

PLoS pathogens, 2020-10, Vol.16 (10), p.e1008784-e1008784

2020

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Essential roles for deubiquitination in Leishmania life cycle progression

PLoS pathogens, 2020-06, Vol.16 (6), p.e1008455

2020

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Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (13), p.5139-5144

2013

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Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules

The Journal of immunology (1950), 2015-11, Vol.195 (9), p.4085-4095

2015

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Generation of peptide-MHC class I complexes through UV-mediated ligand exchange

Nature protocols, 2006-08, Vol.1 (3), p.1120-1132

2006

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Chemical Modification of Influenza CD8+ T-Cell Epitopes Enhances Their Immunogenicity Regardless of Immunodominance

PloS one, 2016-06, Vol.11 (6), p.e0156462-e0156462

2016

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Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (10), p.3825-3830

2008

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UV-Induced Ligand Exchange in MHC Class I Protein Crystals

Journal of the American Chemical Society, 2009-09, Vol.131 (34), p.12298-12304

2009

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Molecular Interactions Underlying the Unusually High Adenosine Affinity of a Novel Trypanosoma brucei Nucleoside Transporter

Molecular pharmacology, 2007-03, Vol.71 (3), p.921-929

2007

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Proteasome Activation by Small Molecules

Cell chemical biology, 2017-06, Vol.24 (6), p.725-736.e7

2017

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Design and use of conditional MHC class I ligands

Nature medicine, 2006-02, Vol.12 (2), p.246-251

2006

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2,N6-Disubstituted Adenosine Analogs with Antitrypanosomal and Antimalarial Activities

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3796-3802

2007

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Peptide Splicing in the Proteasome Creates a Novel Type of Antigen with an Isopeptide Linkage

The Journal of immunology (1950), 2015-11, Vol.195 (9), p.4075-4084

2015

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Ubiquitin-Based Probes Prepared by Total Synthesis To Profile the Activity of Deubiquitinating Enzymes

Chembiochem : a European journal of chemical biology, 2012-10, Vol.13 (15), p.2251-2258

2012

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Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy

Antimicrobial agents and chemotherapy, 2015-11, Vol.59 (11), p.6708-6716

2015

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Transpeptidation and reverse proteolysis and their consequences for immunity

The international journal of biochemistry & cell biology, 2009, Vol.41 (1), p.66-71

2009

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Validation of novel fluorescence assays for the routine screening of drug susceptibilities of Trichomonas vaginalis

Journal of antimicrobial chemotherapy, 2012-04, Vol.67 (4), p.933-943

2012

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Identification of “drugable” molecular targets implicated in cross-presentation by dendritic cells

Molecular immunology, 2012-05, Vol.51 (1), p.29-29

2012

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Development of a Hypersensitive Periodate-Cleavable Amino Acid that is Methionine- and Disulfide-Compatible and its Application in MHC Exchange Reagents for T Cell Characterisation

Chembiochem : a European journal of chemical biology, 2013-01, Vol.14 (1), p.123-131

2013

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2,N 6 -Disubstituted Adenosine Analogs with Antitrypanosomal and Antimalarial Activities

Antimicrobial agents and chemotherapy, 2007-11, Vol.51 (11), p.3796-3802

2007

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A novel chemocleavable linker and its application in MHC class I peptide exchange

Molecular immunology, 2012-05, Vol.51 (1), p.6-7

2012

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Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger

Journal of the American Chemical Society, 2009-09, Vol.131 (34), p.12305-12313

2009

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Generation of Peptide MHC Class I Monomers and Multimers Through Ligand Exchange

Current Protocols in Immunology, 2009-11, Vol.87 (1), p.18.16.1-18.16.20

2009

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High-throughput T-cell epitope discovery through MHC peptide exchange

Methods in molecular biology (Clifton, N.J.), 2009, Vol.524, p.383

2009

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Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5′-carboxamidoadenosine analogues

Bioorganic & medicinal chemistry, 2006-03, Vol.14 (5), p.1618-1629

2006

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Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

Essential roles for deubiquitination in Leishmania life cycle progression

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules

Generation of peptide-MHC class I complexes through UV-mediated ligand exchange

Chemical Modification of Influenza CD8+ T-Cell Epitopes Enhances Their Immunogenicity Regardless of Immunodominance

Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7

UV-Induced Ligand Exchange in MHC Class I Protein Crystals

Molecular Interactions Underlying the Unusually High Adenosine Affinity of a Novel Trypanosoma brucei Nucleoside Transporter

Proteasome Activation by Small Molecules

Design and use of conditional MHC class I ligands

2,N6-Disubstituted Adenosine Analogs with Antitrypanosomal and Antimalarial Activities

Peptide Splicing in the Proteasome Creates a Novel Type of Antigen with an Isopeptide Linkage

Ubiquitin-Based Probes Prepared by Total Synthesis To Profile the Activity of Deubiquitinating Enzymes

Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy

Transpeptidation and reverse proteolysis and their consequences for immunity

Validation of novel fluorescence assays for the routine screening of drug susceptibilities of Trichomonas vaginalis

Identification of “drugable” molecular targets implicated in cross-presentation by dendritic cells

Development of a Hypersensitive Periodate-Cleavable Amino Acid that is Methionine- and Disulfide-Compatible and its Application in MHC Exchange Reagents for T Cell Characterisation

2,N 6 -Disubstituted Adenosine Analogs with Antitrypanosomal and Antimalarial Activities

A novel chemocleavable linker and its application in MHC class I peptide exchange

Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger

Generation of Peptide MHC Class I Monomers and Multimers Through Ligand Exchange

High-throughput T-cell epitope discovery through MHC peptide exchange

Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5′-carboxamidoadenosine analogues

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