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Phenotype switching: tumor cell plasticity as a resistance mechanism and target for therapy

Cancer research (Chicago, Ill.), 2014-11, Vol.74 (21), p.5937-5941

2014

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A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence

Nature (London), 2013-06, Vol.498 (7452), p.109-112

2013

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Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (43), p.13308-13311

2015

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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

Nature communications, 2014-12, Vol.5 (1), p.5712-5712, Article 5712

2014

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Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

Nature (London), 2017-10, Vol.550 (7675), p.270-274

2017

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Heterogeneity in functional genetic screens: friend or foe?

Frontiers in immunology, 2023-06, Vol.14, p.1162706-1162706

2023

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A Twist-Snail Axis Critical for TrkB-Induced Epithelial-Mesenchymal Transition-Like Transformation, Anoikis Resistance, and Metastasis

Molecular and Cellular Biology, 2009-07, Vol.29 (13), p.3722-3737

2009

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XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

BMC bioinformatics, 2018-10, Vol.19 (1), p.366-15, Article 366

2018

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Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence

Carcinogenesis (New York), 2015-11, Vol.36 (11), p.1263-1274

2015

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Reversal of pre-existing NGFR-driven tumor and immune therapy resistance

Nature communications, 2020-08, Vol.11 (1), p.3946-3946, Article 3946

2020

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Rational Cancer Treatment Combinations: An Urgent Clinical Need

Molecular cell, 2020-06, Vol.78 (6), p.1002-1018

2020

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Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (13), p.5139-5144

2013

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Acidity‐mediated induction of FoxP3+ regulatory T cells

European journal of immunology, 2023-06, Vol.53 (6), p.e2250258-n/a

2023

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Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling

Nature communications, 2022-04, Vol.13 (1), p.1923-1923, Article 1923

2022

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Phosphoprotein dynamics of interacting T cells and tumor cells by HySic

Cell reports (Cambridge), 2024-01, Vol.43 (1), p.113598-113598, Article 113598

2024

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Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival

Oncotarget, 2015-12, Vol.6 (41), p.43146-43161

2015

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Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

Nature, 2004-08, Vol.430 (7003), p.1034-1039

2004

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PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks

Journal of proteome research, 2015-10, Vol.14 (10), p.4332-4341

2015

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Senescence-messaging secretome: SMS-ing cellular stress

Nature reviews. Cancer, 2009-02, Vol.9 (2), p.81-94

2009

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Oncogene-induced senescence and melanoma: where do we stand?

Pigment cell and melanoma research, 2011-12, Vol.24 (6), p.1107-1111

Peeper, Daniel S.

2011

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The essence of senescence

Genes & development, 2010-11, Vol.24 (22), p.2463-2479

2010

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Epithelial-mesenchymal transition and senescence: two cancer-related processes are crossing paths

Aging (Albany, NY.), 2010-10, Vol.2 (10), p.735-741

2010

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Phenotypic diversity drives paracrine drug tolerance

EMBO molecular medicine, 2017-08, Vol.9 (8), p.987-989

2017

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Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance

Nature communications, 2023-02, Vol.14 (1), p.672-672, Article 672

2023

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Phenotype switching: tumor cell plasticity as a resistance mechanism and target for therapy

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

Heterogeneity in functional genetic screens: friend or foe?

A Twist-Snail Axis Critical for TrkB-Induced Epithelial-Mesenchymal Transition-Like Transformation, Anoikis Resistance, and Metastasis

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance

Rational Cancer Treatment Combinations: An Urgent Clinical Need

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

Acidity‐mediated induction of FoxP3+ regulatory T cells

Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling

Phosphoprotein dynamics of interacting T cells and tumor cells by HySic

Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks

Senescence-messaging secretome: SMS-ing cellular stress

Oncogene-induced senescence and melanoma: where do we stand?

The essence of senescence

Epithelial-mesenchymal transition and senescence: two cancer-related processes are crossing paths

Phenotypic diversity drives paracrine drug tolerance

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance

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