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Newly Discovered Micropeptide Regulators of SERCA Form Oligomers but Bind to the Pump as Monomers

Journal of molecular biology, 2019-11, Vol.431 (22), p.4429-4443

2019

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A Structural Mechanism for Calcium Transporter Headpiece Closure

The journal of physical chemistry. B, 2015-01, Vol.119 (4), p.1407-1415

2015

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Presenilin 1 is a direct regulator of the cardiac sarco/endoplasmic reticulum calcium pump

Cell calcium (Edinburgh), 2021-11, Vol.99, p.102468-102468, Article 102468

2021

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The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy

eLife, 2018-10, Vol.7

2018

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Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer

Biophysical journal, 2016-09, Vol.111 (6), p.1192-1202

2016

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Dimerization of SERCA2a Enhances Transport Rate and Improves Energetic Efficiency in Living Cells

Biophysical journal, 2020-10, Vol.119 (7), p.1456-1465

2020

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Redistribution of SERCA calcium pump conformers during intracellular calcium signaling

The Journal of biological chemistry, 2018-07, Vol.293 (28), p.10843-10856

2018

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Phosphorylated Phospholamban Stabilizes a Compact Conformation of the Cardiac Calcium-ATPase

Biophysical journal, 2013-10, Vol.105 (8), p.1812-1821

2013

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The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction

Molecular biology of the cell, 2009-03, Vol.20 (5), p.1324-1339

2009

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Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA

eLife, 2021-06, Vol.10

2021

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Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells

Journal of biomolecular screening, 2014-02, Vol.19 (2), p.215-222

2014

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Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α

PloS one, 2019-03, Vol.14 (3), p.e0212888-e0212888

2019

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The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans

Molecular metabolism (Germany), 2021-12, Vol.54, p.101339-101339, Article 101339

2021

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2-Color calcium pump reveals closure of the cytoplasmic headpiece with calcium binding

PloS one, 2012-07, Vol.7 (7), p.e40369-e40369

2012

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ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening

Molecular pharmacology, 2015-07, Vol.88 (1), p.84-94

2015

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Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells

PloS one, 2011-11, Vol.6 (11), p.e27884-e27884

2011

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Protein carbonylation causes sarcoplasmic reticulum Ca2+ overload by increasing intracellular Na+ level in ventricular myocytes

Pflügers Archiv, 2024-07, Vol.476 (7), p.1077-1086

2024

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Phosphomimetic Mutations Increase Phospholamban Oligomerization and Alter the Structure of Its Regulatory Complex

The Journal of biological chemistry, 2008-10, Vol.283 (43), p.28996-29003

2008

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Isoform Specificity of the Na/K-ATPase Association and Regulation by Phospholemman

The Journal of biological chemistry, 2009-09, Vol.284 (39), p.26749-26757

2009

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Pathological mutations in the phospholamban cytoplasmic region affect its topology and dynamics modulating the extent of SERCA inhibition

Biochimica et biophysica acta. Biomembranes, 2024-10, Vol.1866 (7), p.184370, Article 184370

2024

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Spatiotemporally Distinct Protein Kinase D Activation in Adult Cardiomyocytes in Response to Phenylephrine and Endothelin

The Journal of biological chemistry, 2011-09, Vol.286 (38), p.33390-33400

2011

Volltextzugriff (PDF)

Phospholamban Oligomerization, Quaternary Structure, and Sarco(endo)plasmic Reticulum Calcium ATPase Binding Measured by Fluorescence Resonance Energy Transfer in Living Cells

The Journal of biological chemistry, 2008-05, Vol.283 (18), p.12202-12211

2008

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TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions

Retrovirology, 2011-11, Vol.8 (1), p.93-93, Article 93

2011

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FXYD proteins and sodium pump regulatory mechanisms

The Journal of general physiology, 2021-04, Vol.153 (4), p.1

2021

Volltextzugriff (PDF)

anti-apoptotic protein HAX-1 is a regulator of cardiac function

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20776-20781

2009

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Newly Discovered Micropeptide Regulators of SERCA Form Oligomers but Bind to the Pump as Monomers

A Structural Mechanism for Calcium Transporter Headpiece Closure

Presenilin 1 is a direct regulator of the cardiac sarco/endoplasmic reticulum calcium pump

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy

Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer

Dimerization of SERCA2a Enhances Transport Rate and Improves Energetic Efficiency in Living Cells

Redistribution of SERCA calcium pump conformers during intracellular calcium signaling

Phosphorylated Phospholamban Stabilizes a Compact Conformation of the Cardiac Calcium-ATPase

The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction

Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA

Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells

Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α

The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans

2-Color calcium pump reveals closure of the cytoplasmic headpiece with calcium binding

ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening

Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells

Protein carbonylation causes sarcoplasmic reticulum Ca2+ overload by increasing intracellular Na+ level in ventricular myocytes

Phosphomimetic Mutations Increase Phospholamban Oligomerization and Alter the Structure of Its Regulatory Complex

Isoform Specificity of the Na/K-ATPase Association and Regulation by Phospholemman

Pathological mutations in the phospholamban cytoplasmic region affect its topology and dynamics modulating the extent of SERCA inhibition

Spatiotemporally Distinct Protein Kinase D Activation in Adult Cardiomyocytes in Response to Phenylephrine and Endothelin

Phospholamban Oligomerization, Quaternary Structure, and Sarco(endo)plasmic Reticulum Calcium ATPase Binding Measured by Fluorescence Resonance Energy Transfer in Living Cells

TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions

FXYD proteins and sodium pump regulatory mechanisms

anti-apoptotic protein HAX-1 is a regulator of cardiac function

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