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The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

Cell death and differentiation, 2019-09, Vol.26 (9), p.1813-1831

2019

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Cellular and gene therapy

HemaSphere, 2019-06, Vol.3 (Suppl), p.27-n/a

Padua, Rose Ann

2019

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Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens

Nature medicine, 2009-05, Vol.15 (5), p.566-571

2009

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Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event

Blood, 2004-10, Vol.104 (7), p.2035-2043

2004

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Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?

Haematologica (Roma), 2013-01, Vol.98 (1), p.10-22

2013

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Identification of a Patient Cohort with Relapsing Diffuse Large B-Cell Lymphoma with a Low International Prognostic Index in PET/CT Using a 2-Gene (LMO2/TNFRSF9) Scoring System

Acta haematologica, 2020-12, Vol.143 (6), p.600-602

2020

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Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis

Frontiers in immunology, 2018-06, Vol.9, p.1357-1357

2018

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Targeted immunotherapy in acute myeloblastic leukemia : from animals to humans

Cancer Immunology, Immunotherapy, 2005-10, Vol.54 (10), p.933-943

2005

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Histone Deacetylase Inhibitors (HDI) Cause DNA Damage in Leukemia Cells: A Mechanism for Leukemia-Specific HDI-Dependent Apoptosis?

Molecular cancer research, 2006-08, Vol.4 (8), p.563-573

2006

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Identification of JAK2 mutations in canine primary polycythemia

Experimental hematology, 2011-05, Vol.39 (5), p.542-545

2011

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GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

Journal of hematology and oncology, 2016-01, Vol.9 (5), p.5-5, Article 5

2016

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Genetics of Mefloquine Resistance in the Rodent Malaria Parasite Plasmodium chabaudi

Antimicrobial Agents and Chemotherapy, 2003-02, Vol.47 (2), p.709-718

2003

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The Promyelocytic Leukemia Zinc Finger Protein Down-Regulates Apoptosis and Expression of the Proapoptotic BID Protein in Lymphocytes

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (7), p.1898-1903

2004

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Frequent antibody production against RARα in both APL mice and patients

Blood, 2006-09, Vol.108 (6), p.1972-1974

2006

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Prospective international cohort study demonstrates inability of interim PET to predict treatment failure in diffuse large B-cell lymphoma

Journal of Nuclear Medicine, 2014-12, Vol.55 (12), p.1936-1944

2014

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Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ cells

The Journal of experimental medicine, 1997-04, Vol.185 (7), p.1337-1348

1997

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JAK Inhibition Mediates Clonal Selection of RAS Pathway Mutations in Myeloproliferative Neoplasms

Blood, 2022-11, Vol.140 (Supplement 1), p.795-796

2022

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Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Signal transduction and targeted therapy, 2022-02, Vol.7 (1), p.51-51, Article 51

2022

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BCL-2 Inhibition with ABT-199 Shows Efficacy in AML Cell Lines with Synergistic Effects upon Addition of the MEK Inhibitor GDC-0973 and Prolongs Survival in an NAS/BCL-2-Mediated Mouse Model of AML Post-MDS

Blood, 2017-12, Vol.130, p.2613-2613

2017

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The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

p53 activation during ribosome biogenesis regulates normal erythroid differentiation

Cellular and gene therapy

Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens

Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event

Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?

Identification of a Patient Cohort with Relapsing Diffuse Large B-Cell Lymphoma with a Low International Prognostic Index in PET/CT Using a 2-Gene (LMO2/TNFRSF9) Scoring System

Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis

Targeted immunotherapy in acute myeloblastic leukemia : from animals to humans

Histone Deacetylase Inhibitors (HDI) Cause DNA Damage in Leukemia Cells: A Mechanism for Leukemia-Specific HDI-Dependent Apoptosis?

Protocol for qRT-PCR analysis from formalin fixed paraffin embedded tissue sections from diffuse large b-cell lymphoma: Validation of the six-gene predictor score

Identification of JAK2 mutations in canine primary polycythemia

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

Genetics of Mefloquine Resistance in the Rodent Malaria Parasite Plasmodium chabaudi

The Promyelocytic Leukemia Zinc Finger Protein Down-Regulates Apoptosis and Expression of the Proapoptotic BID Protein in Lymphocytes

Frequent antibody production against RARα in both APL mice and patients

Prospective international cohort study demonstrates inability of interim PET to predict treatment failure in diffuse large B-cell lymphoma

Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ cells

JAK Inhibition Mediates Clonal Selection of RAS Pathway Mutations in Myeloproliferative Neoplasms

Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

BCL-2 Inhibition with ABT-199 Shows Efficacy in AML Cell Lines with Synergistic Effects upon Addition of the MEK Inhibitor GDC-0973 and Prolongs Survival in an NAS/BCL-2-Mediated Mouse Model of AML Post-MDS

BCL-2 Inhibitor Venetoclax (ABT-199) and MEK Inhibitor GDC-0973 Synergise to Target AML Progenitors and Overcome Drug Resistance with the Use of PET Scanning in a Mouse Model of HR-MDS to Monitor Response to Treatment

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

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