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WNK signalling pathways in blood pressure regulation

Cellular and molecular life sciences : CMLS, 2017-04, Vol.74 (7), p.1261-1280

2017

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Genetic Markers Regulating Blood Pressure in Extreme Discordant Sib Pairs

Genes, 2023-09, Vol.14 (10), p.1862

2023

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Gordon Syndrome: a continuing story

Pediatric Nephrology, 2015-11, Vol.30 (11), p.1903-1908

O’Shaughnessy, Kevin M.

2015

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Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

Hypertension (Dallas, Tex. 1979), 2012-03, Vol.59 (3), p.587-591

2012

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Role for Germline Mutations and a Rare Coding Single Nucleotide Polymorphism Within the KCNJ5 Potassium Channel in a Large Cohort of Sporadic Cases of Primary Aldosteronism

Hypertension (Dallas, Tex. 1979), 2014-04, Vol.63 (4), p.783-789

2014

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Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success

The Journal of experimental medicine, 2004-10, Vol.200 (8), p.957-965

2004

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Characterisation of the Cullin‐3 mutation that causes a severe form of familial hypertension and hyperkalaemia

EMBO molecular medicine, 2015-10, Vol.7 (10), p.1285-1306

2015

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Treating hypertension in patients with medical comorbidities

BMJ (Online), 2016-02, Vol.352, p.i101

2016

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β1-Adrenoreceptor Polymorphisms and Blood Pressure: 49S Variant Increases Plasma Renin But Not Blood Pressure in Hypertensive Patients

American journal of hypertension, 2019-04, Vol.32 (5), p.447-451

2019

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Role of the WNK‐activated SPAK kinase in regulating blood pressure

EMBO molecular medicine, 2010-02, Vol.2 (2), p.63-75

2010

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Critical role of the SPAK protein kinase CCT domain in controlling blood pressure

Human molecular genetics, 2015-08, Vol.24 (16), p.4545-4558

2015

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Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K

Physiological reports, 2019-11, Vol.7 (22), p.e14280-n/a

2019

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Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma

Journal of hypertension, 2012-09, Vol.30 (9), p.1827-1833

2012

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Authors’ reply to Ninan and Millar and Abou-saleh

BMJ (Online), 2016-04, p.i2253

2016

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Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels

Clinical science (1979), 2018-01, Vol.132 (1), p.145-156

2018

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Novel Insertion Mutation in KCNJ5 Channel Produces Constitutive Aldosterone Release From H295R Cells

Molecular endocrinology (Baltimore, Md.), 2015-10, Vol.29 (10), p.1522-1530

2015

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Role of SPAK and OSR1 signalling in the regulation of NaCl cotransporters

Current opinion in nephrology and hypertension, 2011-09, Vol.20 (5), p.534-540

2011

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Genetics of arterial structure and function: towards new biomarkers for aortic stiffness?

Clinical science (1979), 2008-06, Vol.114 (11), p.661-677

2008

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Renal and Brain Isoforms of WNK3 Have Opposite Effects on NCCT Expression

Journal of the American Society of Nephrology, 2009-06, Vol.20 (6), p.1314-1322

2009

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Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals

Arteriosclerosis, thrombosis, and vascular biology, 2006-08, Vol.26 (8), p.1799-1805

2006

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SPAK and WNK kinases: a new target for blood pressure treatment?

Current opinion in nephrology and hypertension, 2011-01, Vol.20 (1), p.16-22

2011

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Nonadherence to antihypertensive medications amongst patients with uncontrolled hypertension: A retrospective study

Medicine (Baltimore), 2021-04, Vol.100 (14), p.e24654-e24654

2021

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The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4

Canadian journal of physiology and pharmacology, 2010-10, Vol.88 (10), p.986-995

2010

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Salt handling and hypertension

The Journal of clinical investigation, 2004-04, Vol.113 (8), p.1075-1081

2004

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A missense TGFB2 variant p.(Arg320Cys) causes a paradoxical and striking increase in aortic TGFB1/2 expression

European journal of human genetics : EJHG, 2016-01, Vol.25 (1), p.157-160

2016

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WNK signalling pathways in blood pressure regulation

Genetic Markers Regulating Blood Pressure in Extreme Discordant Sib Pairs

Gordon Syndrome: a continuing story

Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

Role for Germline Mutations and a Rare Coding Single Nucleotide Polymorphism Within the KCNJ5 Potassium Channel in a Large Cohort of Sporadic Cases of Primary Aldosteronism

Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success

Characterisation of the Cullin‐3 mutation that causes a severe form of familial hypertension and hyperkalaemia

Treating hypertension in patients with medical comorbidities

β1-Adrenoreceptor Polymorphisms and Blood Pressure: 49S Variant Increases Plasma Renin But Not Blood Pressure in Hypertensive Patients

Role of the WNK‐activated SPAK kinase in regulating blood pressure

Critical role of the SPAK protein kinase CCT domain in controlling blood pressure

Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K

Characterization of a novel somatic KCNJ5 mutation delI157 in an aldosterone-producing adenoma

Authors’ reply to Ninan and Millar and Abou-saleh

Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels

Novel Insertion Mutation in KCNJ5 Channel Produces Constitutive Aldosterone Release From H295R Cells

Role of SPAK and OSR1 signalling in the regulation of NaCl cotransporters

Genetics of arterial structure and function: towards new biomarkers for aortic stiffness?

Renal and Brain Isoforms of WNK3 Have Opposite Effects on NCCT Expression

Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals

SPAK and WNK kinases: a new target for blood pressure treatment?

Nonadherence to antihypertensive medications amongst patients with uncontrolled hypertension: A retrospective study

The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4

Salt handling and hypertension

A missense TGFB2 variant p.(Arg320Cys) causes a paradoxical and striking increase in aortic TGFB1/2 expression

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