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Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (9), p.E1152-E1161

2016

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Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization

ACS chemical neuroscience, 2017-09, Vol.8 (9), p.2065-2077

2017

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Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt

Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (6)

2021

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Orthosteric and Allosteric Dual Targeting of the Nuclear Receptor RORγt with a Bitopic Ligand

ACS chemical biology, 2021-03, Vol.16 (3), p.510-519

2021

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Allosteric small molecule modulators of nuclear receptors

Molecular and cellular endocrinology, 2019-04, Vol.485, p.20-34

2019

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Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.241-259

2020

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Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

ACS chemical neuroscience, 2018-11, Vol.9 (11), p.2639-2654

2018

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Structure–Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt

Journal of medicinal chemistry, 2021-07, Vol.64 (13), p.9238-9258

2021

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Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD

Journal of the American Society of Nephrology, 2018-05, Vol.29 (5), p.1525-1535

2018

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Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist

ChemMedChem, 2020-04, Vol.15 (7), p.561-565

2020

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Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site

ACS medicinal chemistry letters, 2021-04, Vol.12 (4), p.631-639

2021

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Multi-center evaluation of cepheid xpert® xpress SARS-CoV-2 point-of-care test during the SARS-CoV-2 pandemic

Journal of clinical virology, 2020-07, Vol.128, p.104426-104426, Article 104426

2020

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Central serous chorioretinopathy in active endogenous Cushing's syndrome

Scientific reports, 2021-02, Vol.11 (1), p.2748-2748, Article 2748

2021

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Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial

The New England journal of medicine, 2021-04, Vol.384 (15), p.1391-1401

2021

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"Maybe He Was in Love With You?": How to Talk With People in Psychosis

Schizophrenia bulletin, 2020-01, Vol.46 (1), p.6-8

2020

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A Real Case Application of Game Theoretical Concepts in a Complex Decision-Making Process: Case Study ERTMS

Group decision and negotiation, 2022-02, Vol.31 (1), p.153-185

2022

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Bayesian network analysis of antidepressant treatment trajectories

Scientific reports, 2023-05, Vol.13 (1), p.8428-8428, Article 8428

2023

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Limited impact of the COVID-19 pandemic on colorectal cancer care in the Netherlands in 2020

International journal of colorectal disease, 2022-09, Vol.37 (9), p.2013-2020

2022

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Children with atopic dermatitis show increased activity of β‐glucocerebrosidase and stratum corneum levels of glucosylcholesterol that are strongly related to the local cytokine milieu

British journal of dermatology (1951), 2022-06, Vol.186 (6), p.988-996

2022

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Planning target volume margin assessment for online adaptive MR-guided dose-escalation in rectal cancer on a 1.5 T MR-Linac

Radiotherapy and oncology, 2021-09, Vol.162, p.150-155

2021

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Paracrine Proangiogenic Function of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Not Affected by Chronic Kidney Disease

Stem cells international, 2019, Vol.2019, p.1232810-12

2019

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Challenges With the Implementation of Machine Perfusion in Clinical Liver Transplantation

Transplantation, 2024-06, Vol.108 (6), p.1296

2024

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The Game Between Game Theory and Gaming Simulations: Design Choices

Simulation & gaming, 2019-04, Vol.50 (2), p.180-201

2019

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JNK2 in myeloid cells impairs insulin's vasodilator effects in muscle during early obesity development through perivascular adipose tissue dysfunction

American journal of physiology. Heart and circulatory physiology, 2019-08, Vol.317 (2), p.H364-H374

2019

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Reliability of classification for post-traumatic ankle osteoarthritis

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2016-04, Vol.24 (4), p.1332-1337

2016

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Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization

Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt

Orthosteric and Allosteric Dual Targeting of the Nuclear Receptor RORγt with a Bitopic Ligand

Allosteric small molecule modulators of nuclear receptors

Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

Structure–Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt

Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD

Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist

Covalent Occlusion of the RORγt Ligand Binding Pocket Allows Unambiguous Targeting of an Allosteric Site

Multi-center evaluation of cepheid xpert® xpress SARS-CoV-2 point-of-care test during the SARS-CoV-2 pandemic

Central serous chorioretinopathy in active endogenous Cushing's syndrome

Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial

"Maybe He Was in Love With You?": How to Talk With People in Psychosis

A Real Case Application of Game Theoretical Concepts in a Complex Decision-Making Process: Case Study ERTMS

Bayesian network analysis of antidepressant treatment trajectories

Limited impact of the COVID-19 pandemic on colorectal cancer care in the Netherlands in 2020

Children with atopic dermatitis show increased activity of β‐glucocerebrosidase and stratum corneum levels of glucosylcholesterol that are strongly related to the local cytokine milieu

Planning target volume margin assessment for online adaptive MR-guided dose-escalation in rectal cancer on a 1.5 T MR-Linac

Paracrine Proangiogenic Function of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Not Affected by Chronic Kidney Disease

Challenges With the Implementation of Machine Perfusion in Clinical Liver Transplantation

The Game Between Game Theory and Gaming Simulations: Design Choices

JNK2 in myeloid cells impairs insulin's vasodilator effects in muscle during early obesity development through perivascular adipose tissue dysfunction

Reliability of classification for post-traumatic ankle osteoarthritis

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