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Copy neutral loss of heterozygosity: a novel chromosomal lesion in myeloid malignancies

Blood, 2010-04, Vol.115 (14), p.2731-2739

2010

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Clinical Applications of Epigenetic Markers and Epigenetic Profiling in Myeloid Malignancies

Seminars in oncology, 2012-02, Vol.39 (1), p.109-122

McDevitt, Michael A

2012

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Somatic SETBP1 mutations in myeloid malignancies

Nature genetics, 2013-08, Vol.45 (8), p.942-946

2013

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250K Single Nucleotide Polymorphism Array Karyotyping Identifies Acquired Uniparental Disomy and Homozygous Mutations, Including Novel Missense Substitutions of c-Cbl, in Myeloid Malignancies

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (24), p.10349-10357

2008

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Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies

Blood, 2011-04, Vol.117 (17), p.4552-4560

2011

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CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia

Blood, 2011-05, Vol.117 (21), p.e198-e206

2011

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Mutations of E3 Ubiquitin Ligase Cbl Family Members Constitute a Novel Common Pathogenic Lesion in Myeloid Malignancies

Journal of clinical oncology, 2009-12, Vol.27 (36), p.6109-6116

2009

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Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

Nature genetics, 2002-09, Vol.32 (1), p.148-152

2002

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Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis

Blood, 2012-06, Vol.119 (25), p.6109-6117

2012

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A Phase I Study of Topotecan, Carboplatin and the PARP Inhibitor Veliparib in Acute Leukemias, Aggressive Myeloproliferative Neoplasms, and Chronic Myelomonocytic Leukemia

Clinical cancer research, 2017-02, Vol.23 (4), p.899-907

2017

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SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD

PloS one, 2007-11, Vol.2 (11), p.e1225-e1225

2007

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Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of molecular genetics and clinical phenotypes

Haematologica (Roma), 2011-10, Vol.96 (10), p.1462-1469

2011

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Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors

Journal for immunotherapy of cancer, 2021-02, Vol.9 (2), p.e002015

2021

Volltextzugriff (PDF)

A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms

Haematologica (Roma), 2014-04, Vol.99 (4), p.672

2014

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New Lesions Detected by Single Nucleotide Polymorphism Array–Based Chromosomal Analysis Have Important Clinical Impact in Acute Myeloid Leukemia

Journal of clinical oncology, 2009-11, Vol.27 (31), p.5219-5226

2009

Volltextzugriff (PDF)

Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia

Haematologica (Roma), 2013-01, Vol.98 (1), p.107-113

2013

Volltextzugriff (PDF)

Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients

PloS one, 2012-04, Vol.7 (4), p.e34951-e34951

2012

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Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias

Blood, 2011-03, Vol.117 (12), p.3302-3310

2011

Volltextzugriff (PDF)

Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation

Leukemia & lymphoma, 2010-09, Vol.51 (9), p.1711-1719

2010

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A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

The EMBO journal, 1997-07, Vol.16 (13), p.3965-3973

1997

Volltextzugriff (PDF)

The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells

Haematologica (Roma), 2012-08, Vol.97 (8), p.1225-1233

2012

Volltextzugriff (PDF)

Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia

The New England journal of medicine, 2015-09, Vol.373 (10), p.920-928

2015

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Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

Blood, 2009-06, Vol.113 (25), p.6403-6410

2009

Volltextzugriff (PDF)

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A

Blood, 2011-10, Vol.118 (14), p.3932-3941

2011

Volltextzugriff (PDF)

The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence

Molecular and Cellular Biology, 2006-11, Vol.26 (22), p.8252-8266

2006

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Copy neutral loss of heterozygosity: a novel chromosomal lesion in myeloid malignancies

Clinical Applications of Epigenetic Markers and Epigenetic Profiling in Myeloid Malignancies

Somatic SETBP1 mutations in myeloid malignancies

250K Single Nucleotide Polymorphism Array Karyotyping Identifies Acquired Uniparental Disomy and Homozygous Mutations, Including Novel Missense Substitutions of c-Cbl, in Myeloid Malignancies

Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies

CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia

Mutations of E3 Ubiquitin Ligase Cbl Family Members Constitute a Novel Common Pathogenic Lesion in Myeloid Malignancies

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis

A Phase I Study of Topotecan, Carboplatin and the PARP Inhibitor Veliparib in Acute Leukemias, Aggressive Myeloproliferative Neoplasms, and Chronic Myelomonocytic Leukemia

SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD

Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of molecular genetics and clinical phenotypes

Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors

A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms

New Lesions Detected by Single Nucleotide Polymorphism Array–Based Chromosomal Analysis Have Important Clinical Impact in Acute Myeloid Leukemia

Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia

Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients

Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias

Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells

Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia

Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A

The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence

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