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Tumor suppressor p53: from engaging DNA to target gene regulation

Nucleic acids research, 2020-09, Vol.48 (16), p.8848-8869

2020

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Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (3), p.769-780

2018

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Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Molecular cell, 2014-05, Vol.54 (3), p.445-459

2014

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TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

Cell death & disease, 2021-09, Vol.12 (10), p.864-864, Article 864

2021

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Dissecting the DNA binding landscape and gene regulatory network of p63 and p53

eLife, 2020-12, Vol.9

2020

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Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Nature communications, 2017-05, Vol.8 (1), p.15657-15657, Article 15657

2017

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Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil

Nucleic acids research, 2024-10, Vol.52 (20), p.12534-12548

2024

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surviveR: a flexible shiny application for patient survival analysis

Scientific reports, 2023-12, Vol.13 (1), p.22093-22093, Article 22093

2023

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classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes

BMC bioinformatics, 2022-03, Vol.23 (1), p.114-114, Article 114

2022

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BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability

Cancer research (Chicago, Ill.), 2014-05, Vol.74 (10), p.2773-2784

2014

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Evidence for Alteration of EZH2, BMI1, and KDM6A and Epigenetic Reprogramming in Human Papillomavirus Type 16 E6/E7-Expressing Keratinocytes

Journal of Virology, 2011-11, Vol.85 (21), p.10999-11006

2011

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Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

Journal of translational medicine, 2020-09, Vol.18 (1), p.339-339, Article 339

2020

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Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland

Cancer epidemiology, biomarkers & prevention, 2020-01, Vol.29 (1), p.31-38

2020

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Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells

Cell reports (Cambridge), 2023-04, Vol.42 (4), p.112377-112377, Article 112377

2023

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Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer

Cancers, 2020-09, Vol.12 (10), p.2804

2020

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MicroRNA 203 Expression in Keratinocytes Is Dependent on Regulation of p53 Levels by E6

Journal of Virology, 2010-10, Vol.84 (20), p.10644-10652

2010

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Molecular Subtyping Resource: a user-friendly tool for rapid biological discovery from transcriptional data

Disease models & mechanisms, 2022-03, Vol.15 (3)

2022

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A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence

Genes & development, 2015-11, Vol.29 (21), p.2231-2243

2015

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HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures

PLoS pathogens, 2015-06, Vol.11 (6), p.e1004988-e1004988

2015

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The role of p63 in epidermal morphogenesis and neoplasia

Biochemical Society transactions, 2010-02, Vol.38 (Pt 1), p.223-228

2010

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AKT in stromal fibroblasts controls invasion of epithelial cells

Oncotarget, 2013-07, Vol.4 (7), p.1103-1116

2013

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Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach

British journal of cancer, 2019-04, Vol.120 (8), p.827-833

2019

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The Septin-Binding Protein Anillin Is Overexpressed in Diverse Human Tumors

Clinical cancer research, 2005-10, Vol.11 (19), p.6780-6786

2005

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Challenging the Cancer Molecular Stratification Dogma: Intratumoral Heterogeneity Undermines Consensus Molecular Subtypes and Potential Diagnostic Value in Colorectal Cancer

Clinical cancer research, 2016-08, Vol.22 (16), p.4095-4104

2016

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A revised model of TRAIL‐R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis

EMBO reports, 2020-03, Vol.21 (3), p.e49254-n/a

2020

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Tumor suppressor p53: from engaging DNA to target gene regulation

Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

Dissecting the DNA binding landscape and gene regulatory network of p63 and p53

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil

surviveR: a flexible shiny application for patient survival analysis

classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes

BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability

Evidence for Alteration of EZH2, BMI1, and KDM6A and Epigenetic Reprogramming in Human Papillomavirus Type 16 E6/E7-Expressing Keratinocytes

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland

Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells

Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer

MicroRNA 203 Expression in Keratinocytes Is Dependent on Regulation of p53 Levels by E6

Molecular Subtyping Resource: a user-friendly tool for rapid biological discovery from transcriptional data

A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence

HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures

The role of p63 in epidermal morphogenesis and neoplasia

AKT in stromal fibroblasts controls invasion of epithelial cells

Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach

The Septin-Binding Protein Anillin Is Overexpressed in Diverse Human Tumors

Challenging the Cancer Molecular Stratification Dogma: Intratumoral Heterogeneity Undermines Consensus Molecular Subtypes and Potential Diagnostic Value in Colorectal Cancer

A revised model of TRAIL‐R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis

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