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Allosteric regulation of G protein-coupled receptor activity by phospholipids

Nature chemical biology, 2016-01, Vol.12 (1), p.35-39

2016

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How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling

Cell, 2020-12, Vol.183 (7), p.1813-1825.e18

2020

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Single-molecule analysis of ligand efficacy in β2AR–G-protein activation

Nature (London), 2017-06, Vol.547 (7661), p.68-73

2017

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An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

Nature structural & molecular biology, 2020-09, Vol.27 (9), p.829-835

2020

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Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

Nature (London), 2016-07, Vol.535 (7610), p.182-186

2016

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Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8

Biophysical journal, 2024-02, Vol.123 (3), p.152a-152a

Masureel, Matthieu

2024

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Lipids modulate the conformational dynamics of a secondary multidrug transporter

Nature structural & molecular biology, 2016-08, Vol.23 (8), p.744-751

2016

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Structure of the core human NADPH oxidase NOX2

Nature communications, 2022-10, Vol.13 (1), p.6079-11, Article 6079

2022

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Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8

Nature communications, 2023-12, Vol.14 (1), p.7940-7940, Article 7940

2023

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Exposing the molecular heterogeneity of glycosylated biotherapeutics

Nature communications, 2024-04, Vol.15 (1), p.3259-3259, Article 3259

2024

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Protonation drives the conformational switch in the multidrug transporter LmrP

Nature chemical biology, 2014-02, Vol.10 (2), p.149-155

2014

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Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability

mAbs, 2024, Vol.16 (1), p.2309685-2309685

2024

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Structure and dynamics of GPCR signaling complexes

Nature structural & molecular biology, 2018-01, Vol.25 (1), p.4-12

2018

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Interactions between Phosphatidylethanolamine Headgroup and LmrP, a Multidrug Transporter

The Journal of biological chemistry, 2008-04, Vol.283 (14), p.9369-9376

2008

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1124 Discovery and evaluation of bicyclic peptides as modulators of pattern recognition receptors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1237-A1237

2023

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Structure of the neurotensin receptor 1 in complex with β-arrestin 1

Nature (London), 2020-03, Vol.579 (7798), p.303-308

2020

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Catalytic activation of β-arrestin by GPCRs

Nature (London), 2018-05, Vol.557 (7705), p.381-386

2018

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Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Cell, 2015-05, Vol.161 (5), p.1101-1111

2015

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Structural insights into binding specificity, efficacy and bias of a β 2 AR partial agonist

Nature chemical biology, 2018-11, Vol.14 (11), p.1059

2018

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Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

Cell, 2022-11, Vol.185 (24), p.4560-4573.e19

2022

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Activation of the Interleukin-18 Signaling Pathway via Direct Receptor Dimerization in the Absence of Interleukin-18

Journal of interferon & cytokine research, 2024-01, Vol.44 (1), p.37-42

2024

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Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist

Nature chemical biology, 2018-11, Vol.14 (11), p.1059-1066

2018

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Viewing rare conformations of the β₂ adrenergic receptor with pressure-resolved DEER spectroscopy

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (50), p.31824-31831

2020

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Structure of the neurotensin receptor 1 in complex with [beta]-arrestin 1

Nature (London), 2020-03, Vol.579 (7798), p.303

2020

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Arrestin C-tail dynamics regulate activation and GPCR engagement

Biophysical journal, 2023-02, Vol.122 (3), p.49a-49a

2023

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Allosteric regulation of G protein-coupled receptor activity by phospholipids

How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling

Single-molecule analysis of ligand efficacy in β2AR–G-protein activation

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8

Lipids modulate the conformational dynamics of a secondary multidrug transporter

Structure of the core human NADPH oxidase NOX2

Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8

Exposing the molecular heterogeneity of glycosylated biotherapeutics

Protonation drives the conformational switch in the multidrug transporter LmrP

Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability

Structure and dynamics of GPCR signaling complexes

Interactions between Phosphatidylethanolamine Headgroup and LmrP, a Multidrug Transporter

1124 Discovery and evaluation of bicyclic peptides as modulators of pattern recognition receptors

Structure of the neurotensin receptor 1 in complex with β-arrestin 1

Catalytic activation of β-arrestin by GPCRs

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Structural insights into binding specificity, efficacy and bias of a β 2 AR partial agonist

Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

Activation of the Interleukin-18 Signaling Pathway via Direct Receptor Dimerization in the Absence of Interleukin-18

Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist

Viewing rare conformations of the β₂ adrenergic receptor with pressure-resolved DEER spectroscopy

Structure of the neurotensin receptor 1 in complex with [beta]-arrestin 1

Arrestin C-tail dynamics regulate activation and GPCR engagement

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