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ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Nature communications, 2020-11, Vol.11 (1), p.5865-5865, Article 5865

2020

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Effects of in vitro simulated digestion on the antioxidant activity of different Camellia sinensis (L.) Kuntze leaves extracts

European food research & technology, 2022, Vol.248 (1), p.119-128

2022

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A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria

Scientific reports, 2021-11, Vol.11 (1), p.22562-22562, Article 22562

2021

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Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma

Oncogene, 2021-06, Vol.40 (22), p.3799-3814

2021

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Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection

Antiviral research, 2021-06, Vol.190, p.105064-105064, Article 105064

2021

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Effect of in vitro simulated digestion on the anti-Helicobacter Pylori activity of different Propolis extracts

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2183810-2183810

2023

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Pharmacophore-guided repurposing of fibrates and retinoids as GPR40 allosteric ligands with activity on insulin release

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.377-383

2021

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MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212

Antimicrobial Agents and Chemotherapy, 2012-01, Vol.56 (1), p.324-331

2012

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LIM kinases are attractive targets with many macromolecular partners and only a few small molecule regulators

Medicinal research reviews, 2012-09, Vol.32 (5), p.968-998

Manetti, Fabrizio

2012

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Deletion of 82-85 N-Terminal Residues in SARS-CoV-2 Nsp1 Restricts Virus Replication

Viruses, 2024-04, Vol.16 (5), p.689

2024

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Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth

Pharmacological research, 2023-09, Vol.195, p.106858-106858, Article 106858

2023

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Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2382-2394

2022

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Cannabidiol Isolated From Cannabis sativa L. Protects Intestinal Barrier From In Vitro Inflammation and Oxidative Stress

Frontiers in pharmacology, 2021-04, Vol.12, p.641210-641210

2021

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Discovery of 1,4-Naphthoquinones as a New Class of Antiproliferative Agents Targeting GPR55

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.402-406

2019

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Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection

PloS one, 2013-02, Vol.8 (2), p.e56980

2013

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The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme

International journal of molecular sciences, 2022-01, Vol.23 (2), p.771

2022

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The Antimalarial Mefloquine Shows Activity against Mycobacterium abscessus, Inhibiting Mycolic Acid Metabolism

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8533

2021

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Olive Oil Lipophenols Induce Insulin Secretion in 832/13 β-Cell Models

Pharmaceutics, 2021-07, Vol.13 (7), p.1085

2021

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Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria

Computational biology and chemistry, 2017-10, Vol.70, p.133-141

2017

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Identification of the first non-peptidic small molecule inhibitor of the c-Abl/14-3-3 protein–protein interactions able to drive sensitive and Imatinib-resistant leukemia cells to apoptosis

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (20), p.6133-6137

2010

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Quercetin/oleic acid-based G-protein-coupled receptor 40 ligands as new insulin secretion modulators

Future medicinal chemistry, 2017-10, Vol.9 (16), p.1873-1885

2017

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Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.2094-2098

2012

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Recent research results have converted gp120 binders to a therapeutic option for the treatment of HIV-1 infection. A medicinal chemistry point of view

European journal of medicinal chemistry, 2022-02, Vol.229, p.114078-114078, Article 114078

2022

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Targeting protein-protein and protein-nucleic acid interactions for anti-HIV therapy

Current pharmaceutical design, 2011-11, Vol.17 (33), p.3713

2011

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A new nonpeptidic inhibitor of 14-3-3 induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinib

The Journal of pharmacology and experimental therapeutics, 2011-03, Vol.336 (3), p.596

2011

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ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Effects of in vitro simulated digestion on the antioxidant activity of different Camellia sinensis (L.) Kuntze leaves extracts

A molecular spectroscopy approach for the investigation of early phase ochronotic pigment development in Alkaptonuria

Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma

Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection

Effect of in vitro simulated digestion on the anti-Helicobacter Pylori activity of different Propolis extracts

Pharmacophore-guided repurposing of fibrates and retinoids as GPR40 allosteric ligands with activity on insulin release

MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212

LIM kinases are attractive targets with many macromolecular partners and only a few small molecule regulators

Deletion of 82-85 N-Terminal Residues in SARS-CoV-2 Nsp1 Restricts Virus Replication

Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth

Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors

Cannabidiol Isolated From Cannabis sativa L. Protects Intestinal Barrier From In Vitro Inflammation and Oxidative Stress

Discovery of 1,4-Naphthoquinones as a New Class of Antiproliferative Agents Targeting GPR55

Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection

The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme

The Antimalarial Mefloquine Shows Activity against Mycobacterium abscessus, Inhibiting Mycolic Acid Metabolism

Olive Oil Lipophenols Induce Insulin Secretion in 832/13 β-Cell Models

Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria

Identification of the first non-peptidic small molecule inhibitor of the c-Abl/14-3-3 protein–protein interactions able to drive sensitive and Imatinib-resistant leukemia cells to apoptosis

Quercetin/oleic acid-based G-protein-coupled receptor 40 ligands as new insulin secretion modulators

Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

Recent research results have converted gp120 binders to a therapeutic option for the treatment of HIV-1 infection. A medicinal chemistry point of view

Targeting protein-protein and protein-nucleic acid interactions for anti-HIV therapy

A new nonpeptidic inhibitor of 14-3-3 induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinib

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