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Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened

Frontiers in genetics, 2019-06, Vol.10, p.556-556

2019

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Aberrant Sialylation in Cancer: Biomarker and Potential Target for Therapeutic Intervention?

Cancers, 2021-04, Vol.13 (9), p.2014

2021

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ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Nature communications, 2020-11, Vol.11 (1), p.5865-5865, Article 5865

2020

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Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors

Cells (Basel, Switzerland), 2018-12, Vol.7 (12), p.272

2018

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Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma

Oncogene, 2021-06, Vol.40 (22), p.3799-3814

2021

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The Role of Glycosylation in Melanoma Progression

Cells (Basel, Switzerland), 2021-08, Vol.10 (8), p.2136

2021

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Soft Tissue Sarcoma Cancer Stem Cells: An Overview

Frontiers in oncology, 2018-10, Vol.8, p.475-475

2018

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Integration of liposomal irinotecan in the first-line treatment of metastatic pancreatic cancer: try to do not think about the white bear

Therapeutic advances in medical oncology, 2024-01, Vol.16, p.17588359241234487-17588359241234487

2024

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SOX2 as a novel contributor of oxidative metabolism in melanoma cells

Cell communication and signaling, 2018-11, Vol.16 (1), p.87-87, Article 87

2018

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The Multifaceted Role of TGF-β in Gastrointestinal Tumors

Cancers, 2021-08, Vol.13 (16), p.3960

2021

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MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis

Cancers, 2021-09, Vol.13 (19), p.4903

2021

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A Novel atTAK Against Hepatocellular Carcinoma: Overcoming Resistance to Sorafenib

Cellular and molecular gastroenterology and hepatology, 2021-01, Vol.12 (3), p.1151-1152

2021

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Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma

Oncotarget, 2023-05, Vol.14, p.526-527

2023

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Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells

PloS one, 2015-03, Vol.10 (3), p.e0121719-e0121719

2015

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YAP Activation Is Associated with a Worse Prognosis of Poorly Cohesive Gastric Cancer

Journal of personalized medicine, 2023-08, Vol.13 (9), p.1294

2023

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Targeting FGFR Pathway Is Not an Effective Therapeutic Strategy in Patients with Unselected Metastatic Esophagogastric Cancer Resistant to Trastuzumab

Journal of personalized medicine, 2023-03, Vol.13 (3), p.508

2023

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Predictive Biomarkers for a Personalized Approach in Resectable Pancreatic Cancer

Frontiers in surgery, 2022-05, Vol.9, p.866173-866173

2022

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p38 MAPK-dependent phosphorylation of transcription factor SOX2 promotes an adaptive response to BRAF inhibitors in melanoma cells

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102353-102353, Article 102353

2022

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Down-Regulation of SOX2 Underlies the Inhibitory Effects of the Triphenylmethane Gentian Violet on Melanoma Cell Self-Renewal and Survival

Journal of investigative dermatology, 2016-10, Vol.136 (10), p.2059-2069

2016

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Autotaxin Secretion Is a Stromal Mechanism of Adaptive Resistance to TGFβ Inhibition in Pancreatic Ductal Adenocarcinoma

Cancer research (Chicago, Ill.), 2024-01, Vol.84 (1), p.118

2024

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Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe

Cell death & disease, 2018-02, Vol.9 (2), p.142-16, Article 142

2018

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Perioperative NALIRIFOX in patients with resectable pancreatic ductal adenocarcinoma: The open-label, multicenter, phase II nITRO trial

European journal of cancer (1990), 2024-01, Vol.196, p.113430-113430, Article 113430

2024

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Clinical Response to Futibatinib in Patients with High-Level FGFR2-Amplified Advanced Gastric Cancer: Two Case Reports

Clinical drug investigation, 2022-08, Vol.42 (8), p.697-701

2022

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Abstract 1064: Targeting stromal autotaxin synergizes with TGF beta inhibition in pancreatic cancer

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1064-1064

2022

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Exceptional Clinical Response to Alectinib in Pancreatic Acinar Cell Carcinoma With a Novel ALK-KANK4 Gene Fusion

JCO precision oncology, 2022-01, Vol.6, p.e2100400

2022

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Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened

Aberrant Sialylation in Cancer: Biomarker and Potential Target for Therapeutic Intervention?

ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors

Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma

The Role of Glycosylation in Melanoma Progression

Soft Tissue Sarcoma Cancer Stem Cells: An Overview

Integration of liposomal irinotecan in the first-line treatment of metastatic pancreatic cancer: try to do not think about the white bear

SOX2 as a novel contributor of oxidative metabolism in melanoma cells

The Multifaceted Role of TGF-β in Gastrointestinal Tumors

MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis

A Novel atTAK Against Hepatocellular Carcinoma: Overcoming Resistance to Sorafenib

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma

Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells

YAP Activation Is Associated with a Worse Prognosis of Poorly Cohesive Gastric Cancer

Targeting FGFR Pathway Is Not an Effective Therapeutic Strategy in Patients with Unselected Metastatic Esophagogastric Cancer Resistant to Trastuzumab

Predictive Biomarkers for a Personalized Approach in Resectable Pancreatic Cancer

p38 MAPK-dependent phosphorylation of transcription factor SOX2 promotes an adaptive response to BRAF inhibitors in melanoma cells

Down-Regulation of SOX2 Underlies the Inhibitory Effects of the Triphenylmethane Gentian Violet on Melanoma Cell Self-Renewal and Survival

Autotaxin Secretion Is a Stromal Mechanism of Adaptive Resistance to TGFβ Inhibition in Pancreatic Ductal Adenocarcinoma

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe

Perioperative NALIRIFOX in patients with resectable pancreatic ductal adenocarcinoma: The open-label, multicenter, phase II nITRO trial

Clinical Response to Futibatinib in Patients with High-Level FGFR2-Amplified Advanced Gastric Cancer: Two Case Reports

Abstract 1064: Targeting stromal autotaxin synergizes with TGF beta inhibition in pancreatic cancer

Exceptional Clinical Response to Alectinib in Pancreatic Acinar Cell Carcinoma With a Novel ALK-KANK4 Gene Fusion

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