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Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2683-2688

2017

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Splicing of the period Gene 3′-Terminal Intron Is Regulated by Light, Circadian Clock Factors, and Phospholipase C

Molecular and Cellular Biology, 2004-04, Vol.24 (8), p.3359-3372

2004

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How a Circadian Clock Adapts to Seasonal Decreases in Temperature and Day Length

Neuron (Cambridge, Mass.), 1999-09, Vol.24 (1), p.219-230

1999

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Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing

PloS one, 2015-02, Vol.10 (2), p.e0115369-e0115369

2015

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Benzoxazolinone aryl sulfonamides as potent, selective Na v 1.7 inhibitors with in vivo efficacy in a preclinical pain model

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2683-2688

2017

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Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase

Bioorganic & medicinal chemistry letters, 2014-06, Vol.24 (12), p.2737-2740

2014

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Correction: Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing

PloS one, 2015-06, Vol.10 (6), p.e0129641-e0129641

2015

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LRRTM3 Promotes Processing of Amyloid-Precursor Protein by BACE1 and Is a Positional Candidate Gene for Late-Onset Alzheimer's Disease

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (47), p.17967-17972

2006

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Clock-Gated Photic Stimulation of Timeless Expression at Cold Temperatures and Seasonal Adaptation in Drosophila

Journal of biological rhythms, 2006-08, Vol.21 (4), p.256-271

2006

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High-Throughput Screening by RNA Interference: Control of Two Distinct Types of Variance

Cell cycle (Georgetown, Tex.), 2007-04, Vol.6 (8), p.898-901

2007

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Differential Effects of Light and Heat on the Drosophila Circadian Clock Proteins PER and TIM

Molecular and cellular biology, 1998-04, Vol.18 (4), p.2004-2013

1998

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Rat Brain Contains High Levels of Mannose-6-phosphorylated Glycoproteins Including Lysosomal Enzymes and Palmitoyl-Protein Thioesterase, an Enzyme Implicated in Infantile Neuronal Lipofuscinosis

The Journal of biological chemistry, 1996-08, Vol.271 (32), p.19191-19198

1996

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Abstract 2661: Engineered Toxin Bodies (ETBs): Clinical stage immunotoxins with a safer and differentiated profile

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2661-2661

2023

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Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (10), p.2087-2093

2017

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Abstract P4-08-18: Engineered Toxin Bodies Specific for TROP2 Positive Cancers

Cancer research (Chicago, Ill.), 2023-03, Vol.83 (5_Supplement), p.P4-P4-08-18

2023

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P3‐066: A Cellular Expression Model of TAU Hyperphosphorylation and Aggregation That does not Utilize Frontotemporal Dementia Mutations

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_17), p.P842-P843

2016

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Abstract 326: Engineered toxin bodies (ETBs) targeting Trop2

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.326-326

2022

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A CELLULAR EXPRESSION MODEL OF TAU HYPERPHOSPHORYLATION AND AGGREGATION THAT DOES NOT UTILIZE FRONTOTEMPORAL DEMENTIA MUTATIONS

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P842-P843

2016

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Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na v 1.7 inhibitors with pain efficacy in mice

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (10), p.2087-2093

2017

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Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine

Journal of neurochemistry, 2011, Vol.116 (1), p.82-92

2011

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Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function

Molecular and Cellular Biology, 1997-10, Vol.17 (10), p.5915-5922

1997

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Induction of Alzheimer’s-like changes in brain of mice expressing mutant APP fed excess methionine: Methionine diet and Aβ elevation

Journal of neurochemistry, 2011-01, Vol.116 (1), p.82-92

2011

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P1‐120: High methionine diet induces beta‐amyloid–related transcriptional changes in mouse brain

Alzheimer's & dementia, 2010-07, Vol.6 (4S_Part_7), p.S209-S209

2010

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Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing: e0115369

PloS one, 2015-02, Vol.10 (2)

2015

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High methionine diet induces beta-amyloid–related transcriptional changes in mouse brain

Alzheimer's & dementia, 2010-07, Vol.6 (4), p.S209-S209

2010

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Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model

Splicing of the period Gene 3′-Terminal Intron Is Regulated by Light, Circadian Clock Factors, and Phospholipase C

How a Circadian Clock Adapts to Seasonal Decreases in Temperature and Day Length

Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing

Benzoxazolinone aryl sulfonamides as potent, selective Na v 1.7 inhibitors with in vivo efficacy in a preclinical pain model

Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase

Correction: Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing

LRRTM3 Promotes Processing of Amyloid-Precursor Protein by BACE1 and Is a Positional Candidate Gene for Late-Onset Alzheimer's Disease

Clock-Gated Photic Stimulation of Timeless Expression at Cold Temperatures and Seasonal Adaptation in Drosophila

High-Throughput Screening by RNA Interference: Control of Two Distinct Types of Variance

Differential Effects of Light and Heat on the Drosophila Circadian Clock Proteins PER and TIM

Rat Brain Contains High Levels of Mannose-6-phosphorylated Glycoproteins Including Lysosomal Enzymes and Palmitoyl-Protein Thioesterase, an Enzyme Implicated in Infantile Neuronal Lipofuscinosis

Abstract 2661: Engineered Toxin Bodies (ETBs): Clinical stage immunotoxins with a safer and differentiated profile

Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice

Abstract P4-08-18: Engineered Toxin Bodies Specific for TROP2 Positive Cancers

P3‐066: A Cellular Expression Model of TAU Hyperphosphorylation and Aggregation That does not Utilize Frontotemporal Dementia Mutations

Abstract 326: Engineered toxin bodies (ETBs) targeting Trop2

A CELLULAR EXPRESSION MODEL OF TAU HYPERPHOSPHORYLATION AND AGGREGATION THAT DOES NOT UTILIZE FRONTOTEMPORAL DEMENTIA MUTATIONS

Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na v 1.7 inhibitors with pain efficacy in mice

Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine

Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function

Induction of Alzheimer’s-like changes in brain of mice expressing mutant APP fed excess methionine: Methionine diet and Aβ elevation

P1‐120: High methionine diet induces beta‐amyloid–related transcriptional changes in mouse brain

Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing: e0115369

High methionine diet induces beta-amyloid–related transcriptional changes in mouse brain

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