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Therapeutic Effects of FGF23 c‐tail Fc in a Murine Preclinical Model of X‐Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption

Journal of bone and mineral research, 2017-10, Vol.32 (10), p.2062-2073

2017

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Mice Lacking Bioactive IL-12 Can Generate Protective, Antigen-Specific Cellular Responses to Mycobacterial Infection Only if the IL-12 p40 Subunit Is Present

The Journal of immunology (1950), 2002-02, Vol.168 (3), p.1322-1327

2002

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THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses

Annual review of immunology, 1998-01, Vol.16 (1), p.495-521

1998

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Interleukin-12 Is Essential for a Protective Th1 Response in Mice Infected with Cryptococcus neoformans

Infection and Immunity, 1998-10, Vol.66 (10), p.4994-5000

1998

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IL-12 Receptor β2 (IL-12Rβ2)-Deficient Mice Are Defective in IL-12-Mediated Signaling Despite the Presence of High Affinity IL-12 Binding Sites

The Journal of immunology (1950), 2000-12, Vol.165 (11), p.6221-6228

2000

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Characterization of Glucokinase Regulatory Protein-deficient Mice

The Journal of biological chemistry, 2000-03, Vol.275 (11), p.7826-7831

2000

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Reduced incidence and severity of collagen‐induced arthritis in interleukin‐12‐deficient mice

European journal of immunology, 1996-12, Vol.26 (12), p.2933-2938

1996

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SINGLE CELL RNA SEQUENCING OF ULCERATIVE COLITIS AND CROHN'S DISEASE TISSUE SAMPLES INFORMS THE SELECTION OF TREM1 AS A TARGET FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES

Gastroenterology (New York, N.Y. 1943), 2023-04, Vol.164 (4), p.S67-S67

2023

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Vascular endothelial cell lineage-specific promoter in transgenic mice

Development (Cambridge), 1995-04, Vol.121 (4), p.1089-1098

1995

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Pancreas-Infiltrating Th1 Cells and Diabetes Develop in IL-12-Deficient Nonobese Diabetic Mice

The Journal of immunology (1950), 1999-09, Vol.163 (5), p.2960-2968

1999

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SINGLE CELL RNA SEQUENCING OF ULCERATIVE COLITIS AND CROHN'S DISEASE TISSUE SAMPLES INFORMS THE SELECTION OF TREM1 AS A TARGET FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES

Inflammatory bowel diseases, 2023-01, Vol.29 (Supplement_1), p.S52-S53

2023

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Impaired Th2 Subset Development in the Absence of CD4

Immunity (Cambridge, Mass.), 1997-05, Vol.6 (5), p.559-569

1997

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Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (14), p.6812-6817

2019

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IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes

International immunology, 1999-03, Vol.11 (3), p.325-332

1999

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Meetings of the minds: maximizing drug discovery

Disease models & mechanisms, 2008-11, Vol.1 (4-5), p.192-194

Magram, Jeanne

2008

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Abstract LB-B34: LIF as a novel cancer immunotherapy target: modulating the tumor microenvironment with MSC-1, a humanized anti-LIF monoclonal antibody

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.LB-B34-LB-B34

2018

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Abstract 1751: MSC-1 is a first-in-class humanized monoclonal antibody that modulates the tumor microenvironment by inhibiting a novel cancer immunotherapy target, LIF

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1751-1751

2018

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A phase 1 study of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.TPS2602-TPS2602

2018

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Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with mycobacterium tuberculosis

The Journal of experimental medicine, 1997-07, Vol.186 (1), p.39-45

1997

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Therapeutic Effects of FGF23 c-tail Fc in a murine pre-clinical model of X-linked hypophosphatemia via the selective modulation of phosphate reabsorption

Journal of bone and mineral research, 2017-08, Vol.32 (10), p.2062-2073

2017

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Structure-guided engineering fine-tunes pharmacokinetics, tolerability and anti-tumor profile of anti-frizzled antibody

Acta crystallographica. Section A, Foundations and advances, 2018-07, Vol.74 (a1), p.a297-a297

2018

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Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii

The Journal of experimental medicine, 1997-04, Vol.185 (7), p.1261-1273

1997

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Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy

Journal of reproductive immunology, 1997-11, Vol.35 (2), p.111-133

1997

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IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses

Immunity (Cambridge, Mass.), 1996-05, Vol.4 (5), p.471-481

1996

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Regulation of interleukin 12 p40 expression through an NF-kappa B half-site

Molecular and Cellular Biology, 1995-10, Vol.15 (10), p.5258-5267

1995

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Therapeutic Effects of FGF23 c‐tail Fc in a Murine Preclinical Model of X‐Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption

Mice Lacking Bioactive IL-12 Can Generate Protective, Antigen-Specific Cellular Responses to Mycobacterial Infection Only if the IL-12 p40 Subunit Is Present

THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses

Interleukin-12 Is Essential for a Protective Th1 Response in Mice Infected with Cryptococcus neoformans

IL-12 Receptor β2 (IL-12Rβ2)-Deficient Mice Are Defective in IL-12-Mediated Signaling Despite the Presence of High Affinity IL-12 Binding Sites

Characterization of Glucokinase Regulatory Protein-deficient Mice

Reduced incidence and severity of collagen‐induced arthritis in interleukin‐12‐deficient mice

SINGLE CELL RNA SEQUENCING OF ULCERATIVE COLITIS AND CROHN'S DISEASE TISSUE SAMPLES INFORMS THE SELECTION OF TREM1 AS A TARGET FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES

Vascular endothelial cell lineage-specific promoter in transgenic mice

Pancreas-Infiltrating Th1 Cells and Diabetes Develop in IL-12-Deficient Nonobese Diabetic Mice

SINGLE CELL RNA SEQUENCING OF ULCERATIVE COLITIS AND CROHN'S DISEASE TISSUE SAMPLES INFORMS THE SELECTION OF TREM1 AS A TARGET FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES

Impaired Th2 Subset Development in the Absence of CD4

Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies

IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes

Meetings of the minds: maximizing drug discovery

Abstract LB-B34: LIF as a novel cancer immunotherapy target: modulating the tumor microenvironment with MSC-1, a humanized anti-LIF monoclonal antibody

Abstract 1751: MSC-1 is a first-in-class humanized monoclonal antibody that modulates the tumor microenvironment by inhibiting a novel cancer immunotherapy target, LIF

A phase 1 study of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors

Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with mycobacterium tuberculosis

Therapeutic Effects of FGF23 c-tail Fc in a murine pre-clinical model of X-linked hypophosphatemia via the selective modulation of phosphate reabsorption

Structure-guided engineering fine-tunes pharmacokinetics, tolerability and anti-tumor profile of anti-frizzled antibody

Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii

Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy

IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses

Regulation of interleukin 12 p40 expression through an NF-kappa B half-site

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