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JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects

Drugs (New York, N.Y.), 2017-04, Vol.77 (5), p.521-546

2017

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JAK inhibition as a therapeutic strategy for immune and inflammatory diseases

Nature reviews. Drug discovery, 2017-12, Vol.16 (12), p.843

2017

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Selective Janus kinase inhibitors come of age

Nature reviews. Rheumatology, 2019-02, Vol.15 (2), p.74-75

2019

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Type 2 immunity in the skin and lungs

Allergy (Copenhagen), 2020-07, Vol.75 (7), p.1582-1605

2020

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JAK inhibitors: Ten years after

European journal of immunology, 2021-07, Vol.51 (7), p.1615-1627

2021

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The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention

Annual review of medicine, 2015-01, Vol.66 (1), p.311-328

2015

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The JAK-STAT pathway at 30: Much learned, much more to do

Cell, 2022-10, Vol.185 (21), p.3857-3876

2022

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Janus kinases to jakinibs: from basic insights to clinical practice

Rheumatology (Oxford, England), 2019-02, Vol.58 (Supplement_1), p.i4-i16

2019

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Translational and clinical advances in JAK‐STAT biology: The present and future of jakinibs

Journal of leukocyte biology, 2018-09, Vol.104 (3), p.499-514

2018

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Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction

Arthritis & rheumatology (Hoboken, N.J.), 2017-01, Vol.69 (1), p.148-160

2017

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JAK/STAT signaling in regulation of innate lymphoid cells: The gods before the guardians

Immunological reviews, 2018-11, Vol.286 (1), p.148-159

2018

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Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (36), p.10127-10132

2016

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Whole Chromosome Instability induces senescence and promotes SASP

Scientific reports, 2016-10, Vol.6 (1), p.35218-35218, Article 35218

2016

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Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients

Clinical pharmacology and therapeutics, 2018-08, Vol.104 (2), p.364-373

2018

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JAK inhibitors: Is specificity at all relevant?

Seminars in arthritis and rheumatism, 2024-02, Vol.64, p.152327-152327, Article 152327

Gadina, Massimo

2024

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Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550)

The Journal of immunology (1950), 2011-04, Vol.186 (7), p.4234-4243

2011

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Editorial: JAK inhibition in autoimmune and inflammatory diseases

Frontiers in immunology, 2022-12, Vol.13, p.1120281-1120281

2022

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Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies

Arthritis research & therapy, 2020-04, Vol.22 (1), p.69-12, Article 69

2020

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Jakinibs of All Trades: Inhibiting Cytokine Signaling in Immune-Mediated Pathologies

Pharmaceuticals (Basel, Switzerland), 2021-12, Vol.15 (1), p.48

2021

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Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC

Frontiers in immunology, 2019-03, Vol.10, p.479-479

2019

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Transcriptional, Epigenetic and Pharmacological Control of JAK/STAT Pathway in NK Cells

Frontiers in immunology, 2019-10, Vol.10, p.2456-2456

2019

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Brief Report: Deficiency of Complement 1r Subcomponent in Early‐Onset Systemic Lupus Erythematosus: The Role of Disease‐Modifying Alleles in a Monogenic Disease

Arthritis & rheumatology (Hoboken, N.J.), 2017-09, Vol.69 (9), p.1832-1839

2017

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Jakpot! New small molecules in autoimmune and inflammatory diseases

Experimental dermatology, 2014-01, Vol.23 (1), p.7-11

2014

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T-bet is Rapidly Induced by Interferon-γ in Lymphoid and Myeloid Cells

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.15137-15142

2001

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JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects

JAK inhibition as a therapeutic strategy for immune and inflammatory diseases

Selective Janus kinase inhibitors come of age

Type 2 immunity in the skin and lungs

JAK inhibitors: Ten years after

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention

The JAK-STAT pathway at 30: Much learned, much more to do

Janus kinases to jakinibs: from basic insights to clinical practice

Translational and clinical advances in JAK‐STAT biology: The present and future of jakinibs

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction

JAK/STAT signaling in regulation of innate lymphoid cells: The gods before the guardians

Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease

Whole Chromosome Instability induces senescence and promotes SASP

Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients

JAK inhibitors: Is specificity at all relevant?

Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550)

Editorial: JAK inhibition in autoimmune and inflammatory diseases

Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies

Jakinibs of All Trades: Inhibiting Cytokine Signaling in Immune-Mediated Pathologies

Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC

Transcriptional, Epigenetic and Pharmacological Control of JAK/STAT Pathway in NK Cells

Brief Report: Deficiency of Complement 1r Subcomponent in Early‐Onset Systemic Lupus Erythematosus: The Role of Disease‐Modifying Alleles in a Monogenic Disease

Jakpot! New small molecules in autoimmune and inflammatory diseases

T-bet is Rapidly Induced by Interferon-γ in Lymphoid and Myeloid Cells

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